Small-molecule factor D inhibitors targeting the alternative complement pathway

The role of complement in C3 glomerulopathy

(2015) Peter F. Zipfel et al.   MOLECULAR IMMUNOLOGY

Impact of the Common Genetic Associations of Age-Related Macular Degeneration upon Systemic Complement Component C3d Levels

(2014) Tina Ristau et al.   PLoS One

Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria

(2013) Peter Hillmen et al.   BRITISH JOURNAL OF HAEMATOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Infections of People with Complement Deficiencies and Patients Who Have Undergone Splenectomy

(2010) S. Ram et al.   CLINICAL MICROBIOLOGY REVIEWS

Structural biology in fragment-based drug design

(2010) Christopher W Murray et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Towards Prediction of In Vivo Intestinal Absorption Using a 96-Well Caco-2 Assay

(2010) Suzanne Skolnik et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Complement factor D, a novel serine protease

(2010) John E. Volanakis et al.   PROTEIN SCIENCE

Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase Formation

(2010) F. Forneris et al.   SCIENCE

Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab

(2009) A. M. Risitano et al.   BLOOD

Genetic control of the alternative pathway of complement in humans and age-related macular degeneration

(2009) Laura A. Hecker et al.   HUMAN MOLECULAR GENETICS

The spectrum of complement alternative pathway-mediated diseases

(2008) V. Michael Holers   IMMUNOLOGICAL REVIEWS

Systemic Complement Activation in Age-Related Macular Degeneration

(2008) Hendrik P. N. Scholl et al.   PLoS One