Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection

Microbial-derived lithocholic acid and vitamin K2drive the metabolic maturation of pluripotent stem cells-derived and fetal hepatocytes

(2015) Yishai Avior et al.   HEPATOLOGY

Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation

(2014) Daisuke Yamane et al.   NATURE MEDICINE

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation

(2013) Vincent C. Tam et al.   CELL

Use of Laser Capture Microdissection to Map Hepatitis C Virus–Positive Hepatocytes in Human Liver

(2013) Abraham J. Kandathil et al.   GASTROENTEROLOGY

Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver

(2013) Stefan Wieland et al.   HEPATOLOGY

Coordinated elevation of mitochondrial oxidative phosphorylation and autophagy help drive hepatocyte polarization

(2013) D. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flavonoids as dietary regulators of nuclear receptor activity

(2013) Yishai Avior et al.   Food & Function

An Endogenous Accelerator for Viral Gene Expression Confers a Fitness Advantage

(2012) Melissa W. Teng et al.   CELL

HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter

(2012) Alice Kiselyuk et al.   CHEMISTRY & BIOLOGY

Hepatitis C Virus Infection Suppresses GLUT2 Gene Expression via Downregulation of Hepatocyte Nuclear Factor 1 

(2012) C. Matsui et al.   JOURNAL OF VIROLOGY

Nuclear receptors in regenerating liver and hepatocellular carcinoma

(2012) Michele Vacca et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Deregulated MYC expression induces dependence upon AMPK-related kinase 5

(2012) Lidan Liu et al.   NATURE

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells

(2012) Jin Zhang et al.   Nature Protocols

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism

(2011) Jonathan Goldwasser et al.   JOURNAL OF HEPATOLOGY

HCV Causes Chronic Endoplasmic Reticulum Stress Leading to Adaptation and Interference with the Unfolded Protein Response

(2011) Emmanuelle Merquiol et al.   PLoS One

Enhancement of Canonical Wnt/β-Catenin Signaling Activity by HCV Core Protein Promotes Cell Growth of Hepatocellular Carcinoma Cells

(2011) Jiao Liu et al.   PLoS One

Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism

(2011) Livia Vastag et al.   PLoS Pathogens

In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury

(2010) Maria-Louisa Izamis et al.   BIOTECHNOLOGY AND BIOENGINEERING

Hepatitis C Virus, Diabetes and Steatosis: Clinical Evidence in Favor of a Linkage and Role of Genotypes

(2010) Sabine Mihm   DIGESTIVE DISEASES

Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro

(2010) Stephen D. Woodhouse et al.   HEPATOLOGY

Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977

(2010) Eisuke Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures

(2010) A. Ploss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding

(2010) D. Schmidt et al.   SCIENCE

Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

(2010) Deborah L. Diamond et al.   PLoS Pathogens

Hepatitis C virus infection and its clearance alter circulating lipids: Implications for long-term follow-up

(2009) Kathleen E. Corey et al.   HEPATOLOGY

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(2009) Valeria Mas et al.   MOLECULAR MEDICINE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

(2009) J. F. Moxley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance

(2009) S. Kidambi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin

(2008) Yaakov Nahmias et al.   HEPATOLOGY

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

(2008) Joshua Munger et al.   NATURE BIOTECHNOLOGY