Progress and prospects for small-molecule probes of bacterial imaging

Metabolic Profiling of Bacteria by Unnatural C-terminatedD-Amino Acids

(2015) Sean E. Pidgeon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Activity-Based Probe for Studying Crosslinking in Live Bacteria

(2015) Samir Gautam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Streptococcus pneumoniae D39

(2015) Ozden Kocaoglu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Escherichia coli Strain DC2

(2015) Ozden Kocaoglu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MiL-FISH: Multilabeled Oligonucleotides for FluorescenceIn SituHybridization Improve Visualization of Bacterial Cells

(2015) Mario P. Schimak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cell shape dynamics during the staphylococcal cell cycle

(2015) João M. Monteiro et al.   Nature Communications

Facile method to stain the bacterial cell surface for super-resolution fluorescence microscopy

(2014) Ian L. Gunsolus et al.   ANALYST

Unveiling the Inner Workings of Live Bacteria Using Super-Resolution Microscopy

(2014) Hannah H. Tuson et al.   ANALYTICAL CHEMISTRY

An Expanded Set of Fluorogenic Sulfatase Activity Probes

(2014) Elizabeth L. Smith et al.   CHEMBIOCHEM

Chemoenzymatic Synthesis of Trehalose Analogues: Rapid Access to Chemical Probes for Investigating Mycobacteria

(2014) Bailey L. Urbanek et al.   CHEMBIOCHEM

Glycans in pathogenic bacteria – potential for targeted covalent therapeutics and imaging agents

(2014) Van N. Tra et al.   CHEMICAL COMMUNICATIONS

Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins

(2014) Kathrin Lang et al.   CHEMICAL REVIEWS

In situvisualization of newly synthesized proteins in environmental microbes using amino acid tagging and click chemistry

(2014) Roland Hatzenpichler et al.   ENVIRONMENTAL MICROBIOLOGY

In vivo single-molecule imaging of bacterial DNA replication, transcription, and repair

(2014) Mathew Stracy et al.   FEBS LETTERS

Super-resolution imaging of Escherichia coli nucleoids reveals highly structured and asymmetric segregation during fast growth

(2014) Christoph Spahn et al.   JOURNAL OF STRUCTURAL BIOLOGY

Small-Molecule Labeling of Live Cell Surfaces for Three-Dimensional Super-Resolution Microscopy

(2014) Marissa K. Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reconstitution of Peptidoglycan Cross-Linking Leads to Improved Fluorescent Probes of Cell Wall Synthesis

(2014) Matthew D. Lebar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division ofStreptococcus pneumoniae D39

(2014) Ho-Ching T. Tsui et al.   MOLECULAR MICROBIOLOGY

Advances in fluorescence labeling strategies for dynamic cellular imaging

(2014) Kevin M Dean et al.   Nature Chemical Biology

Lipid-linked cell wall precursors regulate membrane association of bacterial actin MreB

(2014) Kathrin Schirner et al.   Nature Chemical Biology

High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization

(2014) S. J. Holden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes

(2014) P. Shieh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live Cell Chemical Profiling of Temporal Redox Dynamics in a Photoautotrophic Cyanobacterium

(2013) Natalie C. Sadler et al.   ACS Chemical Biology

Applications of Small Molecule Probes in Dissecting Mechanisms of Bacterial Virulence and Host Responses

(2013) Aaron W. Puri et al.   BIOCHEMISTRY

Proteome-wide Quantification and Characterization of Oxidation-Sensitive Cysteines in Pathogenic Bacteria

(2013) Xin Deng et al.   Cell Host & Microbe

Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal toChlamydia trachomatis

(2013) Sarina Gloeckl et al.   MOLECULAR MICROBIOLOGY

In vivoorganization of the FtsZ-ring by ZapA and ZapB revealed by quantitative super-resolution microscopy

(2013) Jackson Buss et al.   MOLECULAR MICROBIOLOGY

A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis

(2013) G. W. Liechti et al.   NATURE

Imaging bacterial protein expression using genetically encoded RNA sensors

(2013) Wenjiao Song et al.   NATURE METHODS

Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains

(2013) K. E. Beatty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of secreted bacterial proteins by noncanonical amino acid tagging

(2013) A. Mahdavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ

(2013) Martin Pilhofer et al.   Nature Communications

Selective Penicillin-Binding Protein Imaging Probes Reveal Substructure in Bacterial Cell Division

(2012) Ozden Kocaoglu et al.   ACS Chemical Biology

d-Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen

(2012) M. Sloan Siegrist et al.   ACS Chemical Biology

Click-Mediated Labeling of Bacterial Membranes through Metabolic Modification of the Lipopolysaccharide Inner Core

(2012) Audrey Dumont et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with FluorescentD-Amino Acids

(2012) Erkin Kuru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

Superresolution microscopy for microbiology

(2012) Carla Coltharp et al.   CELLULAR MICROBIOLOGY

Imaging beyond the proteome

(2012) Pamela V. Chang et al.   CHEMICAL COMMUNICATIONS

The Price of Tags in Protein Localization Studies

(2012) William Margolin   JOURNAL OF BACTERIOLOGY

The Helical MreB Cytoskeleton in Escherichia coli MC1000/pLE7 Is an Artifact of the N-Terminal Yellow Fluorescent Protein Tag

(2012) Matthew T. Swulius et al.   JOURNAL OF BACTERIOLOGY

Suite of Activity-Based Probes for Cellulose-Degrading Enzymes

(2012) Lacie M. Chauvigné-Hines et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activity-Based Probe for Histidine Kinase Signaling

(2012) Kaelyn E. Wilke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry

(2012) Benjamin M. Swarts et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reaction-based small-molecule fluorescent probes for chemoselective bioimaging

(2012) Jefferson Chan et al.   Nature Chemistry

Segregation of molecules at cell division reveals native protein localization

(2012) Dirk Landgraf et al.   NATURE METHODS

Enzymatic activation of nitro-aryl fluorogens in live bacterial cells for enzymatic turnover-activated localization microscopy

(2012) Marissa K. Lee et al.   Chemical Science

3D-SIM Super Resolution Microscopy Reveals a Bead-Like Arrangement for FtsZ and the Division Machinery: Implications for Triggering Cytokinesis

(2012) Michael P. Strauss et al.   PLOS BIOLOGY

Development and characterization of improved β-lactone-based anti-virulence drugs targeting ClpP

(2011) Evelyn Zeiler et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A Novel in vivo Cell-Wall Labeling Approach Sheds New Light on Peptidoglycan Synthesis in Escherichia coli

(2011) Nick K. Olrichs et al.   CHEMBIOCHEM

Subcellular Protein Localization by Using a Genetically Encoded Fluorescent Amino Acid

(2011) Godefroid Charbon et al.   CHEMBIOCHEM

Super-resolution microscopy reveals cell wall dynamics and peptidoglycan architecture in ovococcal bacteria

(2011) Richard Wheeler et al.   MOLECULAR MICROBIOLOGY

Binding-Activated Localization Microscopy of DNA Structures

(2011) Ingmar Schoen et al.   NANO LETTERS

Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

(2011) Keriann M Backus et al.   Nature Chemical Biology

Processive Movement of MreB-Associated Cell Wall Biosynthetic Complexes in Bacteria

(2011) J. Dominguez-Escobar et al.   SCIENCE

Coupled, Circumferential Motions of the Cell Wall Synthesis Machinery and MreB Filaments in B. subtilis

(2011) E. C. Garner et al.   SCIENCE

Bacterial cell wall assembly: still an attractive antibacterial target

(2011) Timothy D.H. Bugg et al.   TRENDS IN BIOTECHNOLOGY

A Biosynthetic Strategy for Re-engineering theStaphylococcus aureusCell Wall with Non-native Small Molecules

(2010) James W. Nelson et al.   ACS Chemical Biology

A guide to super-resolution fluorescence microscopy

(2010) Lothar Schermelleh et al.   JOURNAL OF CELL BIOLOGY

Showdomycin as a Versatile Chemical Tool for the Detection of Pathogenesis-Associated Enzymes in Bacteria

(2010) Thomas Böttcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies

(2010) Yan Gong et al.   PLoS One

Architecture of peptidoglycan: more data and more models

(2010) Waldemar Vollmer et al.   TRENDS IN MICROBIOLOGY

Protein Subcellular Localization in Bacteria

(2010) D. Z. Rudner et al.   Cold Spring Harbor Perspectives in Biology

Super-Resolution Fluorescence Microscopy

(2009) Bo Huang et al.   Annual Review of Biochemistry

Structurally Refined β-Lactones as Potent Inhibitors of Devastating Bacterial Virulence Factors

(2009) Thomas Böttcher et al.   CHEMBIOCHEM

Why and How Bacteria Localize Proteins

(2009) L. Shapiro et al.   SCIENCE

Epitope tagging

(2008) Bill Brizzard   BIOTECHNIQUES

Cy3-Cy5 Covalent Heterodimers for Single-Molecule Photoswitching

(2008) Nicholas R. Conley et al.   JOURNAL OF PHYSICAL CHEMISTRY B

β-Lactams as Selective Chemical Probes for the in Vivo Labeling of Bacterial Enzymes Involved in Cell Wall Biosynthesis, Antibiotic Resistance, and Virulence

(2008) Isabell Staub et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors ofStaphylococcus aureus

(2008) Thomas Böttcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY