Combining multi‐omics analysis to identify host‐targeted targets for the control of Brucella infection

Prevalence and risk factors of human brucellosis and malaria among patients with fever in malaria-endemic areas, attending health institutes in Awra and Gulina district, Afar Region, Ethiopia

(2021) Sintayehu Mehari et al.   BMC INFECTIOUS DISEASES

Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

(2020) Fernanda A. H. Batista et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation

(2020) Matthew C Johnson et al.   eLife

Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions

(2020) Anna Plana-Bonamaisó et al.   eLife

In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo

(2020) N. N. Parayath et al.   Nature Communications

Combined proteomic and metabolomic analyses of cerebrospinal fluid from mice with ischemic stroke reveals the effects of a Buyang Huanwu decoction in neurodegenerative disease

(2019) Wei-Hsiang Hsu et al.   PLoS One

Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection

(2018) Marion Rother et al.   Cell Host & Microbe

DRAFT of re- submission to “Molecular Biology of the Cell” Compositional Complexity of Rods and Rings

(2018) Cara R. Schiavon et al.   MOLECULAR BIOLOGY OF THE CELL

Mycophenolic acid induces senescence of vascular precursor cells

(2018) Ellen Go et al.   PLoS One

Oxidative Stress and Renal Fibrosis: Recent Insights for the Development of Novel Therapeutic Strategies

(2018) Wenshan Lv et al.   Frontiers in Physiology

IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways

(2018) Shiyu Duan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments

(2018) S. John Calise et al.   Frontiers in Immunology

High expression of IMPDH2 is associated with aggressive features and poor prognosis of primary nasopharyngeal carcinoma

(2017) Yi Xu et al.   Scientific Reports

On the Integration of In Silico Drug Design Methods for Drug Repurposing

(2017) Eric March-Vila et al.   Frontiers in Pharmacology

Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in pregnant sheep and goats

(2017) Aigerim Mailybayeva et al.   PLoS One

MicroRNA-21 protects against cardiac hypoxia/reoxygenation injury by inhibiting excessive autophagy in H9c2 cellsviathe Akt/mTOR pathway

(2016) Zhouqing Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Antibacterial Flavonoids from Medicinal Plants Covalently Inactivate Type III Protein Secretion Substrates

(2016) Lun K. Tsou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Looking for protein stabilizing drugs with thermal shift assay

(2015) Giuseppina Andreotti et al.   Drug Testing and Analysis

Brucella abortus Cell Cycle and Infection Are Coordinated

(2015) Xavier De Bolle et al.   TRENDS IN MICROBIOLOGY

MiR-99a Antitumor Activity in Human Breast Cancer Cells through Targeting of mTOR Expression

(2014) Yu Hu et al.   PLoS One

PPARγ-Mediated Increase in Glucose Availability Sustains Chronic Brucella abortus Infection in Alternatively Activated Macrophages

(2013) Mariana N. Xavier et al.   Cell Host & Microbe

TAp73 enhances the pentose phosphate pathway and supports cell proliferation

(2013) Wenjing Du et al.   NATURE CELL BIOLOGY

Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

(2012) Magdalena Makowska-Grzyska et al.   BIOCHEMISTRY

Murine and Bovine γδ T Cells Enhance Innate Immunity against Brucella abortus Infections

(2011) Jerod A. Skyberg et al.   PLoS One

ATP-Binding Cassette Systems ofBrucella

(2010) Dominic C. Jenner et al.   COMPARATIVE AND FUNCTIONAL GENOMICS