Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells

(2012) M-J Jung et al.   ONCOGENE

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

(2011) Lan-Lan Smith et al.   Cell Stem Cell

MEIS1, PREP1, and PBX4 Are Differentially Expressed in Acute Lymphoblastic Leukemia: Association of MEIS1 Expression with Higher Proliferation and Chemotherapy Resistance

(2011) Judith A Rosales-Aviña et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

(2011) George S Vassiliou et al.   NATURE GENETICS

Long-Distance Effects of Insertional Mutagenesis

(2011) Ruchi Singhal et al.   PLoS One

CXCL12–CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy

(2010) S Singh et al.   BRITISH JOURNAL OF CANCER

Genetic screens using the piggyBac transposon

(2010) Su Kit Chew et al.   METHODS

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

(2010) Cory M. Johannessen et al.   NATURE

Slingshot: a PiggyBac based transposon system for tamoxifen-inducible ‘self-inactivating’ insertional mutagenesis

(2010) Jun Kong et al.   NUCLEIC ACIDS RESEARCH

Tubulin polymerization modifies cardiac sodium channel expression and gating

(2009) Simona Casini et al.   CARDIOVASCULAR RESEARCH

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells

(2009) W. Wang et al.   GENOME RESEARCH

Transposon-mediated genome manipulation in vertebrates

(2009) Zoltán Ivics et al.   NATURE METHODS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Paclitaxel and vinorelbine, evoked the release of substance P from cultured rat dorsal root ganglion cells through different PKC isoform-sensitive ion channels

(2009) Kanako Miyano et al.   NEUROPHARMACOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Chromosomal transposition of PiggyBac in mouse embryonic stem cells

(2008) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA