Single-nucleus RNA sequencing reveals heterogenous microenvironments and specific drug response between cervical squamous cell carcinoma and adenocarcinoma

Single‐cell transcriptomics dissects epithelial heterogeneity in HPV + cervical adenocarcinoma

(2023) Cong Wang et al.   JOURNAL OF MEDICAL VIROLOGY

Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression

(2023) Chao Liu et al.   Science Advances

Immune checkpoint inhibitor combinations—current and emerging strategies

(2023) Robert J. Walsh et al.   BRITISH JOURNAL OF CANCER

Identification of cervical cancer stem cells using single-cell transcriptomes of normal cervix, cervical premalignant lesions, and cervical cancer

(2023) Tao Zhang et al.   EBioMedicine

Spatiotemporally deciphering the mysterious mechanism of persistent HPV‐induced malignant transition and immune remodelling from HPV‐infected normal cervix, precancer to cervical cancer: Integrating single‐cell RNA‐sequencing and spatial transcriptome

(2023) Chenyan Guo et al.   Clinical and Translational Medicine

Single‐cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment

(2023) Guangxu Cao et al.   EMBO JOURNAL

Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer

(2022) Huocong Huang et al.   CANCER CELL

Single‐cell sequencing reveals the heterogeneity and intratumoral crosstalk in human endometrial cancer

(2022) Zhicheng Yu et al.   CELL PROLIFERATION

Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers

(2022) Frank J. Lowery et al.   SCIENCE

NRG1/ERBB3/ERBB2 Axis Triggers Anchorage-Independent Growth of Basal-like/Triple-Negative Breast Cancer Cells

(2022) Carmen Miano et al.   Cancers

BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity

(2022) Kenshiro Takemoto et al.   CANCER SCIENCE

Single‐cell RNA‐sequencing dissects cellular heterogeneity and identifies two tumor‐suppressing immune cell subclusters in HPV‐related cervical adenosquamous carcinoma

(2022) Xiaohui Li et al.   JOURNAL OF MEDICAL VIROLOGY

Single‐Nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment of Cervical Squamous Cell Carcinoma

(2022) Zhihua Ou et al.   Advanced Science

Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma

(2022) Xiang Wang et al.   Cell Discovery

Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1

(2022) Abigail S. Coetzee et al.   ONCOGENE

Single-cell transcriptomics reveals cellular heterogeneity and molecular stratification of cervical cancer

(2022) Chunbo Li et al.   Communications Biology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

(2021) Nathan D. Mathewson et al.   CELL

A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

(2021) Sijin Cheng et al.   CELL

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Cervical Cancer Immunotherapy: Facts and Hopes

(2021) Louise Ferrall et al.   CLINICAL CANCER RESEARCH

TGFβ Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma

(2021) Ryo Sato et al.   CANCER RESEARCH

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Applications of single-cell sequencing in cancer research: progress and perspectives

(2021) Yalan Lei et al.   Journal of Hematology & Oncology

Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer

(2021) Nicoletta Colombo et al.   NEW ENGLAND JOURNAL OF MEDICINE

p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation

(2021) Feng Yang et al.   Molecular Cancer

Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives

(2021) Xiaoqi Mao et al.   Molecular Cancer

Pan-cancer single-cell landscape of tumor-infiltrating T cells

(2021) Liangtao Zheng et al.   SCIENCE

Beyondcell: targeting cancer therapeutic heterogeneity in single-cell RNA-seq data

(2021) Coral Fustero-Torre et al.   Genome Medicine

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

(2020) Jermaine Goveia et al.   CANCER CELL

High Serum Levels of Cholesterol Increase Anti-tumor Functions of Nature Killer Cells and Reduce Growth of Liver Tumors in Mice

(2020) Wen-Hao Qin et al.   GASTROENTEROLOGY

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

(2020) Katerina Rohlenova et al.   Cell Metabolism

Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient

(2020) Hye Won Lee et al.   Genome Medicine

Comparison of adenocarcinoma and adenosquamous carcinoma prognoses in Chinese patients with FIGO stage IB-IIA cervical cancer following radical surgery

(2020) Xiaojing Zhang et al.   BMC CANCER

scCancer: a package for automated processing of single-cell RNA-seq data in cancer

(2020) Wenbo Guo et al.   BRIEFINGS IN BIOINFORMATICS

Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer

(2020) Sunny Z Wu et al.   EMBO JOURNAL

A scalable SCENIC workflow for single-cell gene regulatory network analysis

(2020) Bram Van de Sande et al.   Nature Protocols

Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

(2020) Jasneet Kaur Khalsa et al.   Nature Communications

CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET

(2020) Shuyang Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Lipid Metabolism in Regulation of Macrophage Functions

(2020) Jiawei Yan et al.   TRENDS IN CELL BIOLOGY

Adoptive cell therapy: Living drugs against cancer

(2020) Tamara Laskowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts

(2020) Angelo L. Grauel et al.   Nature Communications

Tumor endothelial cell-derived cadherin-2 promotes angiogenesis and has prognostic significance for lung adenocarcinoma

(2019) Huiqin Zhuo et al.   Molecular Cancer

Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study

(2019) Hyun Cheol Chung et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer stemness, intratumoral heterogeneity, and immune response across cancers

(2019) Alex Miranda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

(2019) Clotilde Wiel et al.   CELL

TOX promotes the exhaustion of antitumor CD8+ T cells by preventing PD1 degradation in hepatocellular carcinoma

(2019) Xiaochen Wang et al.   JOURNAL OF HEPATOLOGY

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

(2019) Omar Khan et al.   NATURE

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

(2019) Ela Elyada et al.   Cancer Discovery

IL-17A Secreted from Lymphatic Endothelial Cells Promotes Tumorigenesis by Up-regulation of PD-L1 in Hepatoma Stem Cells

(2019) Yuanyan Wei et al.   JOURNAL OF HEPATOLOGY

Delivery strategies of cancer immunotherapy: recent advances and future perspectives

(2019) Zhongwei Zhao et al.   Journal of Hematology & Oncology

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

High-Risk Human Papillomavirus E7 Maintains Stemness Via APH1B In Cervical Cancer Stem-Cell Like Cells

(2019) Shizhou Yang et al.   Cancer Management and Research

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

(2018) Tathiane M. Malta et al.   CELL

FOXO1 regulates VEGFA expression and promotes angiogenesis in healing wounds

(2018) Hyeran Helen Jeon et al.   JOURNAL OF PATHOLOGY

Phenotype molding of stromal cells in the lung tumor microenvironment

(2018) Diether Lambrechts et al.   NATURE MEDICINE

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

(2018) Michael Bartoschek et al.   Nature Communications

Cancer-associated fibroblast (CAF)-derived IL32 promotes breast cancer cell invasion and metastasis via integrin β3–p38 MAPK signalling

(2018) Siyang Wen et al.   CANCER LETTERS

Integrated genomic and molecular characterization of cervical cancer

(2017)   NATURE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Cervical Cancer Stem Cells Selectively Overexpress HPV Oncoprotein E6 that Controls Stemness and Self-Renewal through Upregulation of HES1

(2016) Abhishek Tyagi et al.   CLINICAL CANCER RESEARCH

The Papillomavirus Episteme: a major update to the papillomavirus sequence database

(2016) Koenraad Van Doorslaer et al.   NUCLEIC ACIDS RESEARCH

Design and Analysis of Single-Cell Sequencing Experiments

(2015) Dominic Grün et al.   CELL

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Elevated intrinsic cancer stem cell population in human papillomavirus-associated head and neck squamous cell carcinoma

(2013) Manchao Zhang et al.   CANCER

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS