Th17-inducing dendritic cell vaccines stimulate effective CD4 T cell-dependent antitumor immunity in ovarian cancer that overcomes resistance to immune checkpoint blockade

CCR6 and CXCR6 Identify the Th17 Cells With Cytotoxicity in Experimental Autoimmune Encephalomyelitis

(2022) Lifei Hou et al.   Frontiers in Immunology

A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors

(2022) Diyuan Xue et al.   Science Immunology

Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes

(2022) Hélène Jamann et al.   Frontiers in Immunology

Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment

(2022) Faezzah Baharom et al.   CELL

Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

(2021) Amélie Cachot et al.   Science Advances

Pretreatment Eosinophil Counts in Patients With Advanced or Metastatic Urothelial Carcinoma Treated With Anti-PD-1/PD-L1 Checkpoint Inhibitors

(2021) Jose Mauricio Mota et al.   JOURNAL OF IMMUNOTHERAPY

The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24

(2020) Wai Po Chong et al.   IMMUNITY

TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity

(2020) Stacey N. Harbour et al.   Science Immunology

Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients

(2020) Matthew S. Block et al.   Nature Communications

Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer

(2019) Hadar Reichman et al.   Cancer Immunology Research

Antitumor Activity and Safety of Pembrolizumab in Patients with Advanced Recurrent Ovarian Cancer: Results from the Phase 2 KEYNOTE-100 Study

(2019) U A Matulonis et al.   ANNALS OF ONCOLOGY

Breast cancer statistics, 2019

(2019) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The role of interleukin-17 in tumor development and progression

(2019) Junjie Zhao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Latest clinical evidence and further development of PARP inhibitors in ovarian cancer

(2018) M R Mirza et al.   ANNALS OF ONCOLOGY

Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study

(2018) Laurie L. Brunette et al.   BMC CANCER

The immunopeptidomic landscape of ovarian carcinomas

(2017) Heiko Schuster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation

(2016) Gopinathan Pillai Sreekanth et al.   PLoS One

Characteristics of Long-Term Survivors of Epithelial Ovarian Cancer

(2015) Rosemary D. Cress et al.   OBSTETRICS AND GYNECOLOGY

HLA class I as a predictor of clinical prognosis and CTL infiltration as a predictor of chemosensitivity in ovarian cancer

(2015) Yoshihiko Hirohashi et al.   OncoImmunology

Accumulation of Memory Precursor CD8 T Cells in Regressing Tumors following Combination Therapy with Vaccine and Anti-PD-1 Antibody

(2014) L. Karyampudi et al.   CANCER RESEARCH

Aging and Cytomegalovirus Infection Differentially and Jointly Affect Distinct Circulating T Cell Subsets in Humans

(2014) A. M. Wertheimer et al.   JOURNAL OF IMMUNOLOGY

A New Spontaneously Transformed Syngeneic Model of High-Grade Serous Ovarian Cancer with a Tumor-Initiating Cell Population

(2014) Curtis W. McCloskey et al.   Frontiers in Oncology

Modulation of p38 MAPK signaling enhances dendritic cell activation of human CD4+ Th17 responses to ovarian tumor antigen

(2013) Martin J. Cannon et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

High density of IL-17-producing cells is associated with improved prognosis for advanced epithelial ovarian cancer

(2013) Chunyan Lan et al.   CELL AND TISSUE RESEARCH

Expansion of activated regulatory T cells by myeloid-specific chemokines via an alternative pathway in CSF of bacterial meningitis patients

(2013) Guangzhi Shi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Th17 cell-derived IL-17 is dispensable for B cell antibody production

(2012) Akiko Shibui et al.   CYTOKINE

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Tumor-Infiltrating Programmed Death Receptor-1+ Dendritic Cells Mediate Immune Suppression in Ovarian Cancer

(2011) J. Krempski et al.   JOURNAL OF IMMUNOLOGY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Age-related deregulation of naive T cell homeostasis in elderly humans

(2010) Sara Ferrando-Martínez et al.   AGE

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

Distinct Signal Codes Generate Dendritic Cell Functional Plasticity

(2010) K. Arima et al.   Science Signaling

Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

(2009) I. Kryczek et al.   BLOOD

Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge

(2009) H. Hamada et al.   JOURNAL OF IMMUNOLOGY

T cell subset-specific susceptibility to aging

(2008) Marta Czesnikiewicz-Guzik et al.   CLINICAL IMMUNOLOGY