CCR6 and CXCR6 Identify the Th17 Cells With Cytotoxicity in Experimental Autoimmune Encephalomyelitis

Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis

(2021) Ben J. E. Raveney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation

(2019) Lifei Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Beginner’s Guide to Analyzing and Visualizing Mass Cytometry Data

(2017) Abigail K. Kimball et al.   JOURNAL OF IMMUNOLOGY

Depletion of CD4+ CD25+ regulatory T cells confers susceptibility to experimental autoimmune encephalomyelitis (EAE) in GM-CSF-deficient Csf2 −/− mice

(2016) Debjani Ghosh et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells

(2016) Francesca Ronchi et al.   Nature Communications

The protease cathepsin L regulates Th17 cell differentiation

(2015) Lifei Hou et al.   JOURNAL OF AUTOIMMUNITY

Granzymes Regulate Proinflammatory Cytokine Responses

(2015) Annette C. Wensink et al.   JOURNAL OF IMMUNOLOGY

The granzyme B-Serpinb9 axis controls the fate of lymphocytes after lysosomal stress

(2014) C H Bird et al.   CELL DEATH AND DIFFERENTIATION

SerpinB1 regulates homeostatic expansion of IL-17+ γδ and CD4+ Th17 cells

(2013) Picheng Zhao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

CCR6 regulates EAE pathogenesis by controlling regulatory CD4+T‐cell recruitment to target tissues

(2009) Ricardo Villares et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites

(2009) Jiyun V. Kim et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Inhibition of CCR6 Function Reduces the Severity of Experimental Autoimmune Encephalomyelitis via Effects on the Priming Phase of the Immune Response

(2009) A. Liston et al.   JOURNAL OF IMMUNOLOGY

Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis

(2009) Adam Elhofy et al.   JOURNAL OF NEUROIMMUNOLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response

(2008) Sunil S. Metkar et al.   IMMUNITY

IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice

(2008) Stefan Haak et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET