Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicine

Three-dimensional models: a novel approach for lymphoma research

(2022) Rossi Maura et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Immunocompetent 3D Follicular Lymphoma Model: A Preclinical Tool to Design Tailored Immunotherapies

(2022) Cèlia Dobaño-López et al.   BLOOD

Inhibition of CD39 unleashes macrophage antibody-dependent cellular phagocytosis against B-cell lymphoma

(2022) Mika Casey et al.   LEUKEMIA

Immune-Checkpoint Inhibitors in B-Cell Lymphoma

(2021) Marc Armengol et al.   Cancers

Developing a 3D B Cell Lymphoma Culture System to Model Antibody Therapy

(2021) Russell Foxall et al.   Frontiers in Immunology

Follicular Lymphoma Microenvironment: An Intricate Network Ready for Therapeutic Intervention

(2021) Cèlia Dobaño-López et al.   Cancers

The Tumor Microenvironment in Follicular Lymphoma: Its Pro-Malignancy Role with Therapeutic Potential

(2021) Takashi Watanabe   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma

(2021) Juan Garcia Valero et al.   LEUKEMIA

3D Model Characterization by 2D and 3D Imaging in t(14;18)-Positive B-NHL: Perspectives for In Vitro Drug Screens in Follicular Lymphoma

(2021) Fabien Gava et al.   Cancers

A novel 3D culture model recapitulates primary FL B-cell features and promotes their survival

(2021) Claire Lamaison et al.   Blood Advances

PD-1 blockade restores helper activity of tumor-infiltrating, exhausted PD-1hiCD39+ CD4 T cells

(2020) Camille-Charlotte Balança et al.   JCI Insight

TIGIT and PD-1 mark intratumoral T cells with reduced effector function in B-cell non-Hodgkin lymphoma

(2019) Sarah E Josefsson et al.   Cancer Immunology Research

Daratumumab displays in vitro and in vivo anti-tumor activity in models of B cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens

(2019) Anna Vidal-Crespo et al.   HAEMATOLOGICA

The immune landscape and response to immune checkpoint blockade therapy in lymphoma

(2019) Justin Kline et al.   BLOOD

Follicular lymphoma

(2019) Antonino Carbone et al.   Nature Reviews Disease Primers

Single-cell RNA-Seq of lymphoma cancers reveals malignant B cell types and co-expression of T cell immune checkpoints

(2018) Noemi Andor et al.   BLOOD

T lymphocyte subsets in cancer immunity: Friends or foes

(2018) Dounia Chraa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma

(2018) Cédric Rossi et al.   OncoImmunology

Microfluidic assembly of hydrogel-based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release

(2018) Pooja Sabhachandani et al.   JOURNAL OF CONTROLLED RELEASE

Goodbye flat biology – time for the 3rd and the 4th dimensions

(2017) Mina J. Bissell   JOURNAL OF CELL SCIENCE

3D microvascular model recapitulates the diffuse large B-cell lymphoma tumor microenvironment in vitro

(2017) Robert G. Mannino et al.   LAB ON A CHIP

Expression of LAG-3 defines exhaustion of intratumoral PD-1+ T cells and correlates with poor outcome in follicular lymphoma

(2017) Zhi-Zhang Yang et al.   Oncotarget

Assessment of tumor-infiltrating TCRVγ9Vδ2 γδ lymphocyte abundance by deconvolution of human cancers microarrays

(2017) Marie Tosolini et al.   OncoImmunology

Screening out irrelevant cell-based models of disease

(2016) Peter Horvath et al.   NATURE REVIEWS DRUG DISCOVERY

Large-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas

(2016) Marie Tosolini et al.   OncoImmunology

High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

(2015) Oksana Sirenko et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells

(2015) Ye F. Tian et al.   BIOMATERIALS

PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival

(2015) Z -Z Yang et al.   Blood Cancer Journal

Several immune escape patterns in non-Hodgkin's lymphomas

(2015) Camille Laurent et al.   OncoImmunology

Cell Growth in Aggregates Determines Gene Expression, Proliferation, Survival, Chemoresistance, and Sensitivity to Immune Effectors in Follicular Lymphoma

(2013) Pauline Gravelle et al.   AMERICAN JOURNAL OF PATHOLOGY

The yin and the yang of follicular lymphoma cell niches: Role of microenvironment heterogeneity and plasticity

(2013) Patricia Amé-Thomas et al.   SEMINARS IN CANCER BIOLOGY

Anti-tumor activity of obinutuzumab and rituximab in a follicular lymphoma 3D model

(2013) E Decaup et al.   Blood Cancer Journal

Innate predisposition to immune escape in follicular lymphoma cells

(2012) Pauline Gravelle et al.   OncoImmunology

Three-Dimensional Cell Cultures in Toxicology

(2011) Francesco Pampaloni et al.   Biotechnology & Genetic Engineering Reviews

Follicular programmed death 1–positive lymphocytes in the tumor microenvironment are an independent prognostic factor in follicular lymphoma

(2011) Bill G. Richendollar et al.   HUMAN PATHOLOGY

Human Follicular Lymphoma CD39+-Infiltrating T Cells Contribute to Adenosine-Mediated T Cell Hyporesponsiveness

(2009) S. P. Hilchey et al.   JOURNAL OF IMMUNOLOGY

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

The 2008 WHO classification of lymphomas: implications for clinical practice and translational research

(2009) E. S. Jaffe   Hematology-American Society of Hematology Education Program