An expanded toolkit of drug resistance cassettes for Candida glabrata , Candida auris , and Candida albicans leads to new insights into the ergosterol pathway

Rapid, efficient auxin-inducible protein degradation in Candida pathogens

(2023) Kedric L. Milholland et al.   mSphere

Prevalence and Healthcare Burden of Fungal Infections in the United States, 2018

(2022) Emily Rayens et al.   Open Forum Infectious Diseases

The Set1 Histone H3K4 Methyltransferase Contributes to Azole Susceptibility in a Species-Specific Manner by Differentially Altering the Expression of Drug Efflux Pumps and the Ergosterol Gene Pathway

(2022) Kortany M. Baker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rapid Hypothesis Testing in Candida albicans Clinical Isolates Using a Cloning-Free, Modular, and Recyclable System for CRISPR-Cas9 Mediated Mutant and Revertant Construction

(2022) Junyan Liu et al.   Microbiology Spectrum

An Adjuvant-Based Approach Enables the Use of Dominant HYG and KAN Selectable Markers in Candida albicans

(2022) Sang On Park et al.   mSphere

The SET-domain protein CgSet4 negatively regulates antifungal drug resistance via the ergosterol biosynthesis transcriptional regulator CgUpc2a

(2022) Priyanka Bhakt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants

(2022) Pedro Pais et al.   Microbial Cell

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

(2021) Jeffrey M. Rybak et al.   CLINICAL MICROBIOLOGY AND INFECTION

Antifungal drug resistance: Deciphering the mechanisms governing multidrug resistance in the fungal pathogen Candida glabrata

(2021) Nicole Robbins et al.   CURRENT BIOLOGY

Narrow mutational signatures drive acquisition of multidrug resistance in the fungal pathogen Candida glabrata

(2021) Ewa Ksiezopolska et al.   CURRENT BIOLOGY

Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae

(2020) Tania Jordá et al.   Genes

Distribution of invasive fungal infections: Molecular epidemiology, etiology, clinical conditions, diagnosis and risk factors: A 3-year experience with 490 patients under intensive care

(2020) Zeinab Borjian Boroujeni et al.   MICROBIAL PATHOGENESIS

Erratum for Kim et al., “Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance”

(2019) Sang Hu Kim et al.   mBio

Abrogation of Triazole Resistance upon Deletion of CDR1 in a Clinical Isolate of Candida auris

(2019) Jeffrey M. Rybak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evidence that Ergosterol Biosynthesis Modulates Activity of the Pdr1 Transcription Factor in Candida glabrata

(2019) Bao Gia Vu et al.   mBio

The wide‐ranging phenotypes of ergosterol biosynthesis mutants, and implications for microbial cell factories

(2019) Emily J. Johnston et al.   YEAST

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

(2018) Harley O’Connor Mount et al.   PLoS Genetics

New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi

(2018) Valmik K. Vyas et al.   mSphere

Overexpression or Deletion of Ergosterol Biosynthesis Genes Alters Doubling Time, Response to Stress Agents, and Drug Susceptibility in Saccharomyces cerevisiae

(2018) Somanon Bhattacharya et al.   mBio

Epidemiology and Clinical Features of Invasive Fungal Infection in a US Health Care Network

(2018) Brandon J Webb et al.   Open Forum Infectious Diseases

N- ICE plasmids for generating N- terminal 3 × FLAG tagged genes that allow inducible, constitutive or endogenous expression in Saccharomyces cerevisiae

(2017) Yueping Zhang et al.   YEAST

Use of RNA-Protein Complexes for Genome Editing in Non- albicans Candida Species

(2017) Nora Grahl et al.   mSphere

Genome engineering in the yeast pathogen Candida glabrata using the CRISPR-Cas9 system

(2016) Ludovic Enkler et al.   Scientific Reports

Candida albicans Gene Deletion with a Transient CRISPR-Cas9 System

(2016) Kyunghun Min et al.   mSphere

A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families

(2015) V. K. Vyas et al.   Science Advances

Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes

(2014) Tobias Schwarzmüller et al.   PLoS Pathogens

Candida glabrata: a review of its features and resistance

(2013) C. F. Rodrigues et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Ergosterol biosynthesis in Aspergillus fumigatus: its relevance as an antifungal target and role in antifungal drug resistance

(2013) Laura Alcazar-Fuoli et al.   Frontiers in Microbiology

Sterol C-22 Desaturase ERG5 Mediates the Sensitivity to Antifungal Azoles in Neurospora crassa and Fusarium verticillioides

(2013) Xianyun Sun et al.   Frontiers in Microbiology

Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast

(2012) Carissa L. Young et al.   YEAST

Charge-based Interaction Conserved within Histone H3 Lysine 4 (H3K4) Methyltransferase Complexes Is Needed for Protein Stability, Histone Methylation, and Gene Expression

(2011) Douglas P. Mersman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

(2010) C. M. Martel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Histone H2B C-Terminal Helix Mediates trans-Histone H3K4 Methylation Independent of H2B Ubiquitination

(2010) M. B. Chandrasekharan et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolic control of antifungal drug resistance

(2009) Nicole Robbins et al.   FUNGAL GENETICS AND BIOLOGY

A Conserved Interaction between the SDI Domain of Bre2 and the Dpy-30 Domain of Sdc1 Is Required for Histone Methylation and Gene Expression

(2009) Paul F. South et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Candida aurissp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital

(2009) Kazuo Satoh et al.   MICROBIOLOGY AND IMMUNOLOGY