A mitochondrial checkpoint to adaptive anticancer immunity

Mechanisms of BCL-2 family proteins in mitochondrial apoptosis

(2023) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BCL2 Inhibition Reveals a Dendritic Cell–Specific Immune Checkpoint That Controls Tumor Immunosurveillance

(2023) Liwei Zhao et al.   Cancer Discovery

Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance

(2021) Marco Tigano et al.   NATURE

Reprogramming monocyte-derived macrophages through caspase inhibition

(2021) Paul Chaintreuil et al.   OncoImmunology

Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy

(2020) Takahiro Yamazaki et al.   NATURE IMMUNOLOGY

Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

(2020) Aitziber Buqué et al.   Nature Communications

Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients

(2019) Maria Esperanza Rodriguez-Ruiz et al.   OncoImmunology

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus

(2016) Simone Caielli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

(2014) Michael J. White et al.   CELL

Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

(2014) Anthony Rongvaux et al.   CELL