Persistent Biofluid Small-Molecule Alterations Induced by Trypanosoma cruzi Infection Are Not Restored by Parasite Elimination

Risk Factors for Progression to Chronic Chagas Cardiomyopathy: A Systematic Review and Meta-Analysis

(2023) Melissa K. Cutshaw et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Ensuring Fact-Based Metabolite Identification in Liquid Chromatography–Mass Spectrometry-Based Metabolomics

(2023) Georgios Theodoridis et al.   Analytical Chemistry

Enabling Quantitative Analysis of Surface Small Molecules for Exposomics and Behavioral Studies

(2022) Mitchelle Katemauswa et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Enhancing untargeted metabolomics using metadata-based source annotation

(2022) Julia M. Gauglitz et al.   NATURE BIOTECHNOLOGY

Islet autoantibody seroconversion in type-1 diabetes is associated with metagenome-assembled genomes in infant gut microbiomes

(2022) Li Zhang et al.   Nature Communications

Spatial Metabolomics Reveals Localized Impact of Influenza Virus Infection on the Lung Tissue Metabolome

(2022) Danya A. Dean et al.   mSystems

Impact of Visceral Leishmaniasis on Local Organ Metabolism in Hamsters

(2022) Mahbobeh Lesani et al.   Metabolites

New metabolic signature for Chagas disease reveals sex steroid perturbation in humans and mice

(2022) Makan Golizeh et al.   Heliyon

New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial

(2021) Faustino Torrico et al.   LANCET INFECTIOUS DISEASES

Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology

(2021) Kristyn Hoffman et al.   ACS Infectious Diseases

Identification and Reproducibility of Urinary Metabolomic Biomarkers of Habitual Food Intake in a Cross-Sectional Analysis of the Cancer Prevention Study-3 Diet Assessment Sub-Study

(2021) Ying Wang et al.   Metabolites

Immunometabolism: Towards a Better Understanding the Mechanism of Parasitic Infection and Immunity

(2021) Jing-yue Chen et al.   Frontiers in Immunology

HMDB 5.0: the Human Metabolome Database for 2022

(2021) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease

(2021) Danya A. Dean et al.   PLoS Neglected Tropical Diseases

Mass spectrometry searches using MASST

(2020) Mingxun Wang et al.   NATURE BIOTECHNOLOGY

Developing preliminary blood metabolomics-based biomarkers of insufficient sleep in humans

(2020) Christopher M Depner et al.   SLEEP

Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas disease

(2020) E. Hossain et al.   Science Advances

Feature-based molecular networking in the GNPS analysis environment

(2020) Louis-Félix Nothias et al.   NATURE METHODS

The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure

(2020) Ahmad A. Cluntun et al.   Cell Metabolism

Trypanosoma cruzi amastigotes that persist in the colon during chronic stage murine infections have a reduced replication rate

(2020) Alexander I. Ward et al.   Open Biology

Chagas Cardiomyopathy in Latin America Review

(2019) Jefferson Luis Vieira et al.   Current Cardiology Reports

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

An Animal Model of Acute and Chronic Chagas Disease With the Reticulotropic Y Strain of Trypanosoma cruzi That Depicts the Multifunctionality and Dysfunctionality of T Cells

(2019) Jose Mateus et al.   Frontiers in Immunology

Diet Alters Serum Metabolomic Profiling in the Mouse Model of Chronic Chagas Cardiomyopathy

(2019) Kezia Lizardo et al.   DISEASE MARKERS

Predicting the pathological response to neoadjuvant chemoradiation using untargeted metabolomics in locally advanced rectal cancer

(2018) Huixun Jia et al.   RADIOTHERAPY AND ONCOLOGY

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome

(2018) Laura-Isobel McCall et al.   PLoS Neglected Tropical Diseases

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

(2018) Fernando J Sánchez-Valdéz et al.   eLife

A Method for the Measurement of Salivary Gland Function in Mice

(2018) Harini Bagavant et al.   Jove-Journal of Visualized Experiments

Experimental combination therapy using low doses of benznidazole and allopurinol in mouse models of Trypanosoma cruzi chronic infection

(2018) Marcela Silvina Rial et al.   PARASITOLOGY

q2-longitudinal: Longitudinal and Paired-Sample Analyses of Microbiome Data

(2018) Nicholas A. Bokulich et al.   mSystems

Development of Diagnostics for Chagas Disease: Where Should We Put Our Limited Resources?

(2017) Albert Picado et al.   PLoS Neglected Tropical Diseases

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

(2016) Mingxun Wang et al.   NATURE BIOTECHNOLOGY

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Benznidazole therapy for Chagas disease in asymptomatic Trypanosoma cruzi -seropositive former blood donors: evaluation of the efficacy of different treatment regimens

(2016) André Pires Antunes et al.   Revista da Sociedade Brasileira de Medicina Tropical

Use of a Chagas Urine Nanoparticle Test (Chunap) to Correlate with Parasitemia Levels in T. cruzi/HIV Co-infected Patients

(2016) Yagahira E. Castro-Sesquen et al.   PLoS Neglected Tropical Diseases

Silver nanoparticles induced oxidative and endoplasmic reticulum stresses in mouse tissues: implications for the development of acute toxicity after intravenous administration

(2016) Rui Chen et al.   Toxicology Research

Chagas Cardiomyopathy: Usefulness of EKG and Echocardiogram in a Non-Endemic Country

(2016) Adrián Sánchez-Montalvá et al.   PLoS One

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage

(2016) Amanda Fortes Francisco et al.   Scientific Reports

Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients

(2015) Alex M. Dickens et al.   AIDS

Inflammatory and cardiac biomarkers are differentially expressed in clinical stages of Chagas disease

(2015) S.M. Keating et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

(2015) Carlos A. Morillo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolomics for characterization of gender differences in patients infected with dengue virus

(2015) Nurul Shahfiza et al.   Asian Pacific Journal of Tropical Medicine

Discovery and validation of urinary exposure markers for different plant foods by untargeted metabolomics

(2014) Maj-Britt Schmidt Andersen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Bioluminescence imaging of chronicTrypanosoma cruziinfections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection

(2014) Michael D. Lewis et al.   CELLULAR MICROBIOLOGY

Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease

(2014) Israel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolomic Profiling in Cattle Experimentally Infected with Mycobacterium avium subsp. paratuberculosis

(2014) Jeroen De Buck et al.   PLoS One

Global Metabolomic Profiling of Acute Myocarditis Caused by Trypanosoma cruzi Infection

(2014) Núria Gironès et al.   PLoS Neglected Tropical Diseases

Use of a Novel Chagas Urine Nanoparticle Test (Chunap) for Diagnosis of Congenital Chagas Disease

(2014) Yagahira E. Castro-Sesquen et al.   PLoS Neglected Tropical Diseases

Biomarkers in Trypanosoma cruzi-Infected and Uninfected Individuals with Varying Severity of Cardiomyopathy in Santa Cruz, Bolivia

(2014) Emi E. Okamoto et al.   PLoS Neglected Tropical Diseases

Detection of Soluble Antigen and DNA of Trypanosoma cruzi in Urine Is Independent of Renal Injury in the Guinea Pig Model

(2013) Yagahira E. Castro-Sesquen et al.   PLoS One

Influence of Parasite Load on Renal Function in Mice Acutely Infected with Trypanosoma cruzi

(2013) Juliana Regina Dias Lemos et al.   PLoS One

EMPeror: a tool for visualizing high-throughput microbial community data

(2013) Yoshiki Vázquez-Baeza et al.   GigaScience

IFN-γ Plays a Unique Role in Protection against Low Virulent Trypanosoma cruzi Strain

(2012) Adele A. Rodrigues et al.   PLoS Neglected Tropical Diseases

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

(2011) Warwick B Dunn et al.   Nature Protocols

Plasma  -Type Natriuretic Peptide As a Predictor of Mortality in Community-Dwelling Older Adults With Chagas Disease: 10-Year Follow-up of the Bambui Cohort Study of Aging

(2010) M. F. Lima-Costa et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

(2010) Tomáš Pluskal et al.   BMC BIOINFORMATICS

Chagas disease in Latin American migrants: a Spanish challenge

(2010) A. Pérez-Ayala et al.   CLINICAL MICROBIOLOGY AND INFECTION

Cardiac Involvement with Parasitic Infections

(2010) A. Hidron et al.   CLINICAL MICROBIOLOGY REVIEWS

Usefulness of PCR for monitoring benznidazole response in patients with chronic Chagas' disease: a prospective study in a non-disease-endemic country

(2010) L. Murcia et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification of Novel Diagnostic Serum Biomarkers for Chagas' Disease in Asymptomatic Subjects by Mass Spectrometric Profiling

(2010) M. Ndao et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Chagas disease

(2010) Anis Rassi et al.   LANCET

Clinical and laboratory status of patients with chronic Chagas disease living in a vector-controlled area in Minas Gerais, Brazil, before and nine years after aetiological treatment

(2010) Marta de Lana et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI

(2009) B Zingales et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease

(2009) Cláudio R.F. Marinho et al.   MICROBES AND INFECTION

ProteoWizard: open source software for rapid proteomics tools development

(2008) Darren Kessner et al.   BIOINFORMATICS

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

(2008) Shane R. Wilkinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA