Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy

Anticancer evaluation of methotrexate and curcumin-coencapsulated niosomes against colorectal cancer cell lines

(2022) Navid Mousazadeh et al.   Nanomedicine

Lipid-polymer nanocarrier platform enables X-ray induced photodynamic therapy against human colorectal cancer cells

(2022) Rui Sang et al.   BIOMEDICINE & PHARMACOTHERAPY

pH-Responsive PEGylated Niosomal Nanoparticles as an Active-Targeting Cyclophosphamide Delivery System for Gastric Cancer Therapy

(2022) Farnaz Khodabakhsh et al.   MOLECULES

Engineered hyaluronic acid-decorated niosomal nanoparticles for controlled and targeted delivery of epirubicin to treat breast cancer

(2022) Amirreza Mansoori-Kermani et al.   Materials Today Bio

Preparation, Optimization and In-Vitro Evaluation of Curcumin-Loaded Niosome@calcium Alginate Nanocarrier as a New Approach for Breast Cancer Treatment

(2021) Iman Akbarzadeh et al.   Biology-Basel

In-Vitro Application of Magnetic Hybrid Niosomes: Targeted siRNA-Delivery for Enhanced Breast Cancer Therapy

(2021) Viktor Maurer et al.   Pharmaceutics

PEGylated Nanographene Oxide in Combination with Near-Infrared Laser Irradiation as a Smart Nanocarrier in Colon Cancer Targeted Therapy

(2021) Milena Georgieva et al.   Pharmaceutics

Multifunctional stimuli-responsive niosomal nanoparticles for co-delivery and co-administration of gene and bioactive compound: In vitro and in vivo studies

(2021) Najmeh Alsadat Abtahi et al.   CHEMICAL ENGINEERING JOURNAL

Functionalized niosomes as a smart delivery device in cancer and fungal infection

(2021) Priyadarshi Aparajay et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Taxanes loaded polymersomes as an emerging polymeric nanocarrier for cancer therapy

(2021) Vanshikha Singh et al.   EUROPEAN POLYMER JOURNAL

CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer

(2021) Shanshan Gao et al.   ONCOGENE

Global colorectal cancer burden in 2020 and projections to 2040

(2021) Yue Xi et al.   Translational Oncology

Nanoarchitectonics of Multifunctional Niosomes for Advanced Drug Delivery

(2021) Denitsa B. Momekova et al.   ACS Omega

Methylene blue-loaded niosome: preparation, physicochemical characterization, and in vivo wound healing assessment

(2020) Ali Farmoudeh et al.   Drug Delivery and Translational Research

YC-1 potentiates the antitumor activity of gefitinib by inhibiting HIF-1α and promoting the endocytic trafficking and degradation of EGFR in gefitinib-resistant non-small-cell lung cancer cells

(2020) Hui Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hyaluronic Acid Capped, Irinotecan and Gene Co-Loaded Lipid-Polymer Hybrid Nanocarrier-Based Combination Therapy Platform for Colorectal Cancer

(2020) Zhiyu Wang et al.   Drug Design Development and Therapy

Hydrogen Sulfide Mediates Tumor Cell Resistance to Thioredoxin Inhibitor

(2020) Zhimin Mao et al.   Frontiers in Oncology

Lysine-embedded cellulose-based nanosystem for efficient dual-delivery of chemotherapeutics in combination cancer therapy

(2020) Sevil Vaghefi Moghaddam et al.   CARBOHYDRATE POLYMERS

Luminescent silicon-based nanocarrier for drug delivery in colorectal cancer cells

(2020) Gonçalo A. Marcelo et al.   DYES AND PIGMENTS

Niosome‐encapsulated tobramycin reduced antibiotic resistance and enhanced antibacterial activity against multidrug‐resistant clinical strains of Pseudomonas aeruginosa

(2020) Mojtaba Hedayati Ch et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Optimization, physicochemical characterization, and antimicrobial activity of a novel simvastatin nano-niosomal gel against E. coli and S. aureus

(2020) Iman Akbarzadeh et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Rising incidence of early-onset colorectal cancer — a call to action

(2020) Naohiko Akimoto et al.   Nature Reviews Clinical Oncology

Immune checkpoint inhibition in syngeneic mouse cancer models by a silicasome nanocarrier delivering a GSK3 inhibitor

(2020) Sean D. Allen et al.   BIOMATERIALS

An illustrated review on nonionic surfactant vesicles (niosomes) as an approach in modern drug delivery: Fabrication, characterization, pharmaceutical, and cosmetic applications

(2020) Moein Masjedi et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Primary endothelial–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia

(2019) Rafal Bartoszewski et al.   FASEB JOURNAL

Colon cancer stem cells: Potential target for the treatment of colorectal cancer

(2019) Riya Gupta et al.   CANCER BIOLOGY & THERAPY

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

(2019) NaNa Keum et al.   Nature Reviews Gastroenterology & Hepatology

Preparation, characterization, and evaluation of the anticancer activity of artemether-loaded nano-niosomes against breast cancer

(2019) Mohamad Javad Mirzaei-Parsa et al.   Breast Cancer

Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro

(2018) Simona Serini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Propolis-based niosomes as oromuco-adhesive films: A randomized clinical trial of a therapeutic drug delivery platform for the treatment of oral recurrent aphthous ulcers

(2018) Mona G. Arafa et al.   Scientific Reports

pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models

(2017) Federica Rinaldi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Cancer drug delivery in the nano era: An overview and perspectives

(2017) Zhen Li et al.   ONCOLOGY REPORTS

Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy

(2017) Tianchi Yu et al.   YONSEI MEDICAL JOURNAL

Niosomes: A Strategy toward Prevention of Clinically Significant Drug Incompatibilities

(2017) Hebatallah B. Mohamed et al.   Scientific Reports

Niosomes as Nanoparticular Drug Carriers: Fundamentals and Recent Applications

(2016) Didem Ag Seleci et al.   Journal of Nanomaterials

Further Evolution of Multifunctional Niosomes Based on Pluronic Surfactant: Dual Active Targeting and Drug Combination Properties

(2016) Lorena Tavano et al.   LANGMUIR

Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy

(2015) Peng Zhang et al.   BIOMATERIALS

Stimuli-sensitive nanopreparations for combination cancer therapy

(2014) Aditi Jhaveri et al.   JOURNAL OF CONTROLLED RELEASE

Thioredoxin-1 inhibitor, 1-methylpropyl 2-imidazolyl disulfide, inhibits the growth, migration and invasion of colorectal cancer cell lines

(2014) FULE WANG et al.   ONCOLOGY REPORTS

Hypoxia inducible factor pathway inhibitors as anticancer therapeutics

(2013) Sarah K Burroughs et al.   Future Medicinal Chemistry

PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis

(2013) BO RA YOU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Apoptosis Signal-Regulating Kinase 1–Thioredoxin Complex Dissociation by Capsaicin Causes Pancreatic Tumor Growth Suppression by Inducing Apoptosis

(2012) Kartick C. Pramanik et al.   ANTIOXIDANTS & REDOX SIGNALING

Small-molecule inhibitors of the HIF pathway and synthetic lethal interactions

(2012) Dylan T Jones et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Green tea catechins ameliorate adipose insulin resistance by improving oxidative stress

(2012) Jingqi Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Niosomes as a potential drug delivery system for increasing the efficacy and safety of nystatin

(2011) Mohammed Shafik El-Ridy et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

Effects of YC-1 on Hypoxia-Inducible Factor 1 Alpha in Hypoxic Human Bladder Transitional Carcinoma Cell Line T24 Cells

(2011) Yangle Li et al.   UROLOGIA INTERNATIONALIS

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

A randomized phase II study of PX-12, an inhibitor of thioredoxin in patients with advanced cancer of the pancreas following progression after a gemcitabine-containing combination

(2010) Ramesh K. Ramanathan et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY