Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension
Authors
Keywords
-
Journal
Expert Review of Clinical Pharmacology
Volume -, Issue -, Pages 1-9
Publisher
Informa UK Limited
Online
2023-10-28
DOI
10.1080/17512433.2023.2277330
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension
- (2023) Akshay S. Desai et al. NEW ENGLAND JOURNAL OF MEDICINE
- Delivery of RNA Therapeutics: The Great Endosomal Escape!
- (2022) Steven F. Dowdy et al. Nucleic Acid Therapeutics
- Conventional Vasopressor and Vasopressor‐Sparing Strategies to Counteract the Blood Pressure–Lowering Effect of Small Interfering RNA Targeting Angiotensinogen
- (2022) Estrellita Uijl et al. Journal of the American Heart Association
- Small interfering RNA (siRNA): discovery, pharmacology and clinical development – an introductory review
- (2022) Priyanga Ranasinghe et al. BRITISH JOURNAL OF PHARMACOLOGY
- Small Interfering RNA Therapeutics in Hypertension: A Viewpoint on Vasopressor and Vasopressor‐Sparing Strategies for Counteracting Blood Pressure Lowering by Angiotensinogen–Targeting Small Interfering RNA
- (2022) Priyanga Ranasinghe et al. Journal of the American Heart Association
- The growth of siRNA-based therapeutics: updated clinical studies
- (2021) M. May Zhang et al. BIOCHEMICAL PHARMACOLOGY
- Hypertension: Current trends and future perspectives
- (2021) Paul G. Hunter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
- (2021) Bin Zhou et al. LANCET
- Medication Adherence and Blood Pressure Control: A Scientific Statement From the American Heart Association
- (2021) Niteesh K. Choudhry et al. HYPERTENSION
- Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans
- (2021) Hirofumi Watanabe et al. JCI Insight
- Targeting angiotensinogen with RNA-based therapeutics
- (2020) Liwei Ren et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Nonadherence to antihypertensive medications is related to pill burden in apparent treatment-resistant hypertensive individuals
- (2020) Alexander J. Lawson et al. JOURNAL OF HYPERTENSION
- Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
- (2020) Kausik K. Ray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia
- (2020) Frederick J. Raal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates
- (2020) Christopher R Brown et al. NUCLEIC ACIDS RESEARCH
- Adverse pregnancy outcomes associated with first‐trimester exposure to angiotensin‐converting enzyme inhibitors or angiotensin II receptor blockers: A systematic review and meta‐analysis
- (2020) Nida Buawangpong et al. Pharmacology Research & Perspectives
- The current state and future directions of RNAi-based therapeutics
- (2019) Ryan L. Setten et al. NATURE REVIEWS DRUG DISCOVERY
- Adherence in Hypertension
- (2019) Michel Burnier et al. CIRCULATION RESEARCH
- Cardiorenal Syndrome
- (2019) Ujjala Kumar et al. CARDIOLOGY CLINICS
- Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen
- (2019) Estrellita Uijl et al. HYPERTENSION
- National Rates of Nonadherence to Antihypertensive Medications Among Insured Adults With Hypertension, 2015
- (2019) Tiffany E. Chang et al. HYPERTENSION
- Nocturnal Hypertension
- (2018) Kazuomi Kario HYPERTENSION
- Reversal of siRNA-mediated gene silencing in vivo
- (2018) Ivan Zlatev et al. NATURE BIOTECHNOLOGY
- Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology
- (2018) Steven J. Forrester et al. PHYSIOLOGICAL REVIEWS
- Structural Foundations of RNA Silencing by Argonaute
- (2017) Jessica Sheu-Gruttadauria et al. JOURNAL OF MOLECULAR BIOLOGY
- Nonadherence to antihypertensive drugs
- (2017) Tadesse Melaku Abegaz et al. MEDICINE
- Synthesis of 5′-GalNAc-Conjugated Oligonucleotides: A Comparison of Solid and Solution-Phase Conjugation Strategies
- (2017) et al. MOLECULES
- Overcoming cellular barriers for RNA therapeutics
- (2017) Steven F Dowdy NATURE BIOTECHNOLOGY
- Angiotensin II for the Treatment of Vasodilatory Shock
- (2017) Ashish Khanna et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Highly Durable RNAi Therapeutic Inhibitor of PCSK9
- (2017) Kevin Fitzgerald et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pharmacokinetics and biodistribution of recently-developed siRNA nanomedicines
- (2016) Jinho Park et al. ADVANCED DRUG DELIVERY REVIEWS
- Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
- (2016) Dena Ettehad et al. LANCET
- Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
- (2015) Anders Wittrup et al. NATURE BIOTECHNOLOGY
- A holistic approach to targeting disease with polymeric nanoparticles
- (2015) Christopher J. Cheng et al. NATURE REVIEWS DRUG DISCOVERY
- European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring
- (2014) Gianfranco Parati et al. JOURNAL OF HYPERTENSION
- Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing
- (2014) Jayaprakash K. Nair et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice
- (2014) Thazha P. Prakash et al. NUCLEIC ACIDS RESEARCH
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Efficacy and safety of dual blockade of the renin-angiotensin system: meta-analysis of randomised trials
- (2013) H. Makani et al. BMJ-British Medical Journal
- Nighttime Home Blood Pressure and the Risk of Hypertensive Target Organ Damage
- (2012) Joji Ishikawa et al. HYPERTENSION
- Comparison of Dopamine and Norepinephrine in the Treatment of Shock
- (2010) Daniel De Backer et al. NEW ENGLAND JOURNAL OF MEDICINE
- A three-dimensional view of the molecular machinery of RNA interference
- (2009) Martin Jinek et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started