Association of pronounced elevation of NET formation and nucleosome biomarkers with mortality in patients with septic shock

NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study

(2022) Laure Morimont et al.   Biomolecules

Neutrophils, functions beyond host defense

(2022) Jin Wang et al.   CELLULAR IMMUNOLOGY

Plasma Nucleosomes Are Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome

(2021) Nadir Yehya et al.   CRITICAL CARE MEDICINE

Circulating Nucleosomes as Potential Markers to Monitor COVID-19 Disease Progression

(2021) Etienne Cavalier et al.   Frontiers in Molecular Biosciences

Sepsis-Induced Immunosuppression

(2021) Lisa K. Torres et al.   Annual Review of Physiology

Neutrophil extracellular traps: from physiology to pathology

(2021) Andres Hidalgo et al.   CARDIOVASCULAR RESEARCH

Neutrophil Extracellular Traps Exacerbate Ischemic Brain Damage

(2021) Congqin Li et al.   MOLECULAR NEUROBIOLOGY

Effects of Neutrophil Extracellular Traps in Patients With Septic Coagulopathy and Their Interaction With Autophagy

(2021) Jia-Yu Mao et al.   Frontiers in Immunology

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4

(2020) Theodora-Dorita Tsourouktsoglou et al.   Cell Reports

Citrullination of extracellular histone H3.1 reduces antibacterial activity and exacerbates its proteolytic degradation

(2020) Lloyd Tanner et al.   Journal of Cystic Fibrosis

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

(2019) Marrah E Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neutrophil Extracellular Traps

(2019) Charlotte Thålin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An emerging role of neutrophils and NETosis in chronic inflammation and fibrosis in systemic lupus erythematosus (SLE) and ANCA-associated vasculitides (AAV): Implications for the pathogenesis and treatment

(2019) Eleni Frangou et al.   AUTOIMMUNITY REVIEWS

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

Advances in the understanding and treatment of sepsis-induced immunosuppression

(2017) Fabienne Venet et al.   Nature Reviews Nephrology

The role of extracellular histone in organ injury

(2017) Eleanor Silk et al.   Cell Death & Disease

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sepsis-induced immune dysfunction: can immune therapies reduce mortality?

(2016) Matthew J. Delano et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients

(2015) Karin C.A.A. Wildhagen et al.   THROMBOSIS RESEARCH

Citrullinated histone H3: A novel target for the treatment of sepsis

(2014) Yongqing Li et al.   SURGERY

Circulating nucleosomes and severity of illness in children suffering from meningococcal sepsis treated with protein C

(2012) Sacha Zeerleder et al.   CRITICAL CARE MEDICINE

Gene expression profiling reveals the defining features of monocytes from septic patients with compensatory anti-inflammatory response syndrome

(2012) Ping-bo Xu et al.   JOURNAL OF INFECTION

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens