Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells

3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics

(2021) Hyogeun Shin et al.   Nature Communications

Generation of homogeneous midbrain organoids with in vivo- like cellular composition facilitates neurotoxin-based Parkinson's disease modeling

(2020) Tae Hwan Kwak et al.   STEM CELLS

Infection of bat and human intestinal organoids by SARS-CoV-2

(2020) Jie Zhou et al.   NATURE MEDICINE

Human organoids: model systems for human biology and medicine

(2020) Jihoon Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease

(2020) Sarah Louise Nickels et al.   Stem Cell Research

Multifunctional multi-shank neural probe for investigating and modulating long-range neural circuits in vivo

(2019) Hyogeun Shin et al.   Nature Communications

Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond

(2018) Chun Liu et al.   DEVELOPMENT

Millifluidic culture improves human midbrain organoid vitality and differentiation

(2018) Emanuel Berger et al.   LAB ON A CHIP

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

(2018) Lorna J. Hale et al.   Nature Communications

Guided self-organization and cortical plate formation in human brain organoids

(2017) Madeline A Lancaster et al.   NATURE BIOTECHNOLOGY

Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

(2017) Momoko Watanabe et al.   Cell Reports

Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells

(2017) Anna S. Monzel et al.   Stem Cell Reports

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro

(2016) Elena Matsa et al.   Cell Stem Cell

Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

(2016) Junghyun Jo et al.   Cell Stem Cell

Stem Cell Models of Human Brain Development

(2016) Iva Kelava et al.   Cell Stem Cell

Engineering Stem Cell Organoids

(2016) Xiaolei Yin et al.   Cell Stem Cell

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

(2016) Chongyuan Luo et al.   Cell Reports

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

WITHDRAWN—a resource for withdrawn and discontinued drugs

(2015) Vishal B. Siramshetty et al.   NUCLEIC ACIDS RESEARCH

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

Parameters for burst detection

(2014) Douglas J. Bakkum et al.   Frontiers in Computational Neuroscience

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

The adult human brain in preclinical drug development

(2008) Mike Dragunow   NATURE REVIEWS DRUG DISCOVERY