Diagnostic performance and clinical impact of blood metagenomic next-generation sequencing in ICU patients suspected monomicrobial and polymicrobial bloodstream infections

Cross-protection and cross-feeding between Klebsiella pneumoniae and Acinetobacter baumannii promotes their co-existence

(2023) Lucie Semenec et al.   Nature Communications

Diagnostic value of bronchoalveolar lavage fluid metagenomic next-generation sequencing in pediatric pneumonia

(2022) Wenhua Deng et al.   Frontiers in Cellular and Infection Microbiology

Clinical Characteristics and the Effect of Timing for Metagenomic Next-Generation Sequencing in Critically Ill Patients with Sepsis

(2022) Dehua He et al.   Infection and Drug Resistance

The diagnostic value of metagenomic next⁃generation sequencing in infectious diseases

(2021) Hongxia Duan et al.   BMC INFECTIOUS DISEASES

Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing

(2021) Yi-Yi Qian et al.   Frontiers in Cellular and Infection Microbiology

Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Pulmonary Infectious Pathogens From Bronchoalveolar Lavage Samples

(2021) Yuqian Chen et al.   Frontiers in Cellular and Infection Microbiology

A Comparison of Blood Pathogen Detection Among Droplet Digital PCR, Metagenomic Next-Generation Sequencing, and Blood Culture in Critically Ill Patients With Suspected Bloodstream Infections

(2021) Bangchuan Hu et al.   Frontiers in Microbiology

Clinical Evaluation of an Improved Metagenomic Next-Generation Sequencing Test for the Diagnosis of Bloodstream Infections

(2021) Chendi Jing et al.   CLINICAL CHEMISTRY

Microbial Cell-Free DNA Identifies Etiology of Bloodstream Infections, Persists Longer Than Conventional Blood Cultures, and its Duration of Detection is Associated with Metastatic Infection in Patients with Staphylococcus aureus and Gram-Negative Bacteremia

(2021) Emily M Eichenberger et al.   CLINICAL INFECTIOUS DISEASES

Metagenomic Next-Generation Sequencing of Bloodstream Microbial Cell-Free Nucleic Acid in Children With Suspected Sepsis in Pediatric Intensive Care Unit

(2021) Gangfeng Yan et al.   Frontiers in Cellular and Infection Microbiology

The Diagnostic Value of Metagenomic Next–Generation Sequencing in Lower Respiratory Tract Infection

(2021) Yan Zheng et al.   Frontiers in Cellular and Infection Microbiology

Pre-digest of unprotected DNA by Benzonase improves the representation of living skin bacteria and efficiently depletes host DNA

(2021) Yacine Amar et al.   Microbiome

Exploring the Clinical Utility of Metagenomic Next-Generation Sequencing in the Diagnosis of Pulmonary Infection

(2021) Guijuan Xie et al.   Infectious Diseases and Therapy

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

(2021) Laura Evans et al.   INTENSIVE CARE MEDICINE

A Retrospective Paired Comparison Between Untargeted Next Generation Sequencing and Conventional Microbiology Tests With Wisely Chosen Metagenomic Sequencing Positive Criteria

(2021) Hanyu Qin et al.   Frontiers in Medicine

Metagenomics next-generation sequencing tests take the stage in the diagnosis of lower respiratory tract infections

(2021) Zhenli Diao et al.   Journal of Advanced Research

Metagenomic next-generation sequencing technology for detection of pathogens in blood of critically ill patients

(2020) Shike Geng et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease

(2019) Timothy A. Blauwkamp et al.   Nature Microbiology

Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid

(2019) Steve Miller et al.   GENOME RESEARCH

Comparison of the Performance of Three Blood Culture Systems in a Chinese Tertiary-Care Hospital

(2019) Guanlin Li et al.   Frontiers in Cellular and Infection Microbiology

Antibiotic Use in the Intensive Care Unit: Optimization and De-Escalation

(2018) Maureen Campion et al.   JOURNAL OF INTENSIVE CARE MEDICINE

OUP accepted manuscript

(2018)   CLINICAL INFECTIOUS DISEASES

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

(2018) Wei Gu et al.   Annual Review of Pathology-Mechanisms of Disease

Transcriptionally Active Lung Microbiome and Its Association with Bacterial Biomass and Host Inflammatory Status

(2018) Lili Ren et al.   mSystems

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Next-Generation Sequencing for Diagnosis and Tailored Therapy: A Case Report of Astrovirus-Associated Progressive Encephalitis

(2015) M.-L. Frémond et al.   Journal of the Pediatric Infectious Diseases Society

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour

(2014) Ricard Ferrer et al.   CRITICAL CARE MEDICINE

A Randomized Trial of Protocol-Based Care for Early Septic Shock

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Overall burden of bloodstream infection and nosocomial bloodstream infection in North America and Europe

(2013) M. Goto et al.   CLINICAL MICROBIOLOGY AND INFECTION

Mixed bloodstream infections involving bacteria and Candida spp.

(2013) Emilio Bouza et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Predictors of positive blood cultures in critically ill patients: a retrospective evaluation

(2012) Marco Previsdomini et al.   CROATIAN MEDICAL JOURNAL

Characteristics and Outcomes of Polymicrobial Bloodstream Infections in the Emergency Department: A Matched Case-control Study

(2010) Jiun-Nong Lin et al.   ACADEMIC EMERGENCY MEDICINE

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS