Antibiotic Use in the Intensive Care Unit: Optimization and De-Escalation

Extended infusion of beta-lactam antibiotics: optimizing therapy in critically-ill patients in the era of antimicrobial resistance

(2017) Nesrine A. Rizk et al.   Expert Review of Anti-Infective Therapy

Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy

(2017) Caleb J.P. Economou et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Think twice: A cognitive perspective of an antibiotic timeout intervention to improve antibiotic use

(2017) Makoto Jones et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Evaluation of the Accelerate Pheno System for Fast Identification and Antimicrobial Susceptibility Testing from Positive Blood Cultures in Bloodstream Infections Caused by Gram-Negative Pathogens

(2017) Matthias Marschal et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Procalcitonin and white blood cells, combined predictors of infection in cardiac surgery patients

(2017) María Heredia-Rodríguez et al.   JOURNAL OF SURGICAL RESEARCH

The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection

(2017) John E. Mazuski et al.   Surgical Infections

Frequency, associated factors and outcome of multi-drug-resistant intensive care unit-acquired pneumonia among patients colonized with extended-spectrum β-lactamase-producing Enterobacteriaceae

(2017) Keyvan Razazi et al.   Annals of Intensive Care

Executive Summary: Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America

(2016) Tamar F. Barlam et al.   CLINICAL INFECTIOUS DISEASES

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

(2016) Andre C. Kalil et al.   CLINICAL INFECTIOUS DISEASES

Experience With Rapid Microarray-Based Diagnostic Technology and Antimicrobial Stewardship for Patients With Gram-Positive Bacteremia

(2016) Elizabeth A. Neuner et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Clinical Impact of Laboratory Implementation of Verigene BC-GN Microarray-Based Assay for Detection of Gram-Negative Bacteria in Positive Blood Cultures

(2016) Tamar Walker et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Multicenter Assessment of Gram Stain Error Rates

(2016) Linoj P. Samuel et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Health care–associated pneumonia in the intensive care unit: Guideline-concordant antibiotics and outcomes

(2016) Russell T. Attridge et al.   JOURNAL OF CRITICAL CARE

Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial

(2016) Evelien de Jong et al.   LANCET INFECTIOUS DISEASES

De-Escalation of Antibiotics Does Not Increase Mortality in Critically Ill Surgical Patients

(2016) Kristin C. Turza et al.   Surgical Infections

Evaluation of a Pharmacist-Directed Vancomycin Dosing and Monitoring Pilot Program at a Tertiary Academic Medical Center

(2015) Kathleen A. Marquis et al.   ANNALS OF PHARMACOTHERAPY

Safety and Outcome of Pharmacy-Led Vancomycin Dosing and Monitoring

(2015) Hisham Momattin et al.   CHEMOTHERAPY

A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit

(2015) Alexis Tabah et al.   CLINICAL INFECTIOUS DISEASES

Impact of a Rapid Microarray-Based Assay for Identification of Positive Blood Cultures for Treatment Optimization for Patients with Streptococcal and Enterococcal Bacteremia

(2015) Danya G. Roshdy et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Trial of Short-Course Antimicrobial Therapy for Intraabdominal Infection

(2015) Robert G. Sawyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Infections Caused by Resistant Gram-Negative Bacteria: Epidemiology and Management

(2015) Keith S. Kaye et al.   PHARMACOTHERAPY

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial

(2015) Nick Daneman et al.   Trials

Antibiotic Self-stewardship: Trainee-Led Structured Antibiotic Time-outs to Improve Antimicrobial Use

(2014) Todd C. Lee et al.   ANNALS OF INTERNAL MEDICINE

Patients presenting to the hospital with MRSA pneumonia: differentiating characteristics and outcomes with empiric treatment

(2014) Emi Minejima et al.   BMC INFECTIOUS DISEASES

Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome

(2014) Jan De Waele et al.   BMC INFECTIOUS DISEASES

Prolonged infusion versus intermittent boluses of β-lactam antibiotics for treatment of acute infections: a meta-analysis

(2014) Jocelyn Teo et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Evaluation of the Nanosphere Verigene BC-GN Assay for Direct Identification of Gram-Negative Bacilli and Antibiotic Resistance Markers from Positive Blood Cultures and Potential Impact for More-Rapid Antibiotic Interventions

(2014) J. T. Hill et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Association of Excessive Duration of Antibiotic Therapy for Intra-Abdominal Infection with Subsequent Extra-Abdominal Infection and Death: A Study of 2,552 Consecutive Infections

(2014) Lin M. Riccio et al.   Surgical Infections

Risk Factors for Drug-Resistant Pathogens in Community-acquired and Healthcare-associated Pneumonia

(2013) Yuichiro Shindo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Predictive Value of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Swab PCR Assay for MRSA Pneumonia

(2013) Benjamin Dangerfield et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Extended-Infusion Cefepime Reduces Mortality in Patients with Pseudomonas aeruginosa Infections

(2013) Karri A. Bauer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America

(2013) H. W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Healthcare-Associated Pneumonia Does Not Accurately Identify Potentially Resistant Pathogens: A Systematic Review and Meta-Analysis

(2013) James D. Chalmers et al.   CLINICAL INFECTIOUS DISEASES

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry and PCR-based rapid diagnosis of Staphylococcus aureus bacteraemia

(2013) O. Clerc et al.   CLINICAL MICROBIOLOGY AND INFECTION

When Pharmacodynamics Trump Costs: An Antimicrobial Stewardship Program’s Approach to Selecting Optimal Antimicrobial Agents

(2013) Debra A. Goff et al.   CLINICAL THERAPEUTICS

A Clinical Trial Comparing Physician Prompting With an Unprompted Automated Electronic Checklist to Reduce Empirical Antibiotic Utilization

(2013) Curtis H. Weiss et al.   CRITICAL CARE MEDICINE

Impact of Regular Collaboration Between Infectious Diseases and Critical Care Practitioners on Antimicrobial Utilization and Patient Outcome*

(2013) Ramzy H. Rimawi et al.   CRITICAL CARE MEDICINE

Stewardship Approach for Optimizing Antimicrobial Therapy through Use of a Rapid Microarray Assay on Blood Cultures Positive for Enterococcus Species

(2013) A. Sango et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A negative nares screen in combination with absence of clinical risk factors can be used to identify patients with very low likelihood of methicillin-resistant Staphylococcus aureus infection in a Veterans Affairs hospital

(2012) Sadao Jinno et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Audit and Feedback to Reduce Broad-Spectrum Antibiotic Use among Intensive Care Unit Patients A Controlled Interrupted Time Series Analysis

(2012) Marion Elligsen et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Risk factors for infection/colonization caused by resistant Gram negative bacilli in critically ill patients (An observational study of 1633 critically ill patients)

(2012) Anupama Vasudevan et al.   PREVENTIVE MEDICINE

Present and future of prophylactic antibiotics for severe acute pancreatitis

(2012) Kun Jiang   WORLD JOURNAL OF GASTROENTEROLOGY

Prospective audit for antimicrobial stewardship in intensive care: Impact on resistance and clinical outcomes

(2011) Carlos A. DiazGranados   AMERICAN JOURNAL OF INFECTION CONTROL

Strategies for Reduction in Duration of Antibiotic Use in Hospitalized Patients

(2011) Y. Hayashi et al.   CLINICAL INFECTIOUS DISEASES

Mild colonic diverticulitis can be treated without antibiotics. a case-control study

(2011) N. de Korte et al.   Colorectal Disease

Initial management of pneumonia and sepsis: factors associated with improved outcome

(2011) R. Menendez et al.   EUROPEAN RESPIRATORY JOURNAL

Empiric Combination Antibiotic Therapy Is Associated with Improved Outcome against Sepsis Due to Gram-Negative Bacteria: a Retrospective Analysis

(2010) S. T. Micek et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Influence of Empiric Therapy with a  -Lactam Alone or Combined with an Aminoglycoside on Prognosis of Bacteremia Due to Gram-Negative Microorganisms

(2010) J. A. Martinez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Management of antibiotic resistance in the intensive care unit setting

(2010) Nicola Petrosillo et al.   Expert Review of Anti-Infective Therapy

Reassessment of intravenous antibiotic therapy using a reminder or direct counselling

(2010) P. Lesprit et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Short course antibiotic therapy for Gram-negative hospital-acquired pneumonia in the critically ill

(2010) R.J. Pugh et al.   JOURNAL OF HOSPITAL INFECTION

Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial

(2010) Lila Bouadma et al.   LANCET

Prediction of Infection Due to Antibiotic-Resistant Bacteria by Select Risk Factors for Health Care–Associated Pneumonia

(2008) Andrew F. Shorr et al.   ARCHIVES OF INTERNAL MEDICINE

Utility of Gram stain in the clinical management of suspected ventilator-associated pneumonia

(2008) M. Albert et al.   JOURNAL OF CRITICAL CARE