Proline catabolism is a key factor facilitating Candida albicans pathogenicity

GNP2 Encodes a High-Specificity Proline Permease in Candida albicans

(2022) Enrico Garbe et al.   mBio

Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions

(2022) Lian Narunsky-Haziza et al.   CELL

YEASTRACT+: a portal for the exploitation of global transcription regulation and metabolic model data in yeast biotechnology and pathogenesis

(2022) Miguel Cacho Teixeira et al.   NUCLEIC ACIDS RESEARCH

Intravital Imaging of Candida albicans Identifies Differential In Vitro and In Vivo Filamentation Phenotypes for Transcription Factor Deletion Mutants

(2021) Rohan S. Wakade et al.   mSphere

The Multifaceted Roles of Proline in Cell Behavior

(2021) Eduardo J. Patriarca et al.   Frontiers in Cell and Developmental Biology

Interactions of Both Pathogenic and Nonpathogenic CUG Clade Candida Species with Macrophages Share a Conserved Transcriptional Landscape

(2021) Andrew W. Pountain et al.   mBio

Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality

(2020) Katherine Lagree et al.   PLoS Genetics

The gut, the bad and the harmless: Candida albicans as a commensal and opportunistic pathogen in the intestine

(2020) Carol A Kumamoto et al.   CURRENT OPINION IN MICROBIOLOGY

Survival Strategies of Pathogenic Candida Species in Human Blood Show Independent and Specific Adaptations

(2020) Philipp Kämmer et al.   mBio

Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism

(2020) Mohammad Zulkifli et al.   Nature Communications

Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans

(2020) Fitz Gerald S. Silao et al.   PLoS Pathogens

Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in Candida albicans

(2019) Fitz Gerald S. Silao et al.   PLoS Genetics

A metabolomic study of the effect of Candida albicans glutamate dehydrogenase deletion on growth and morphogenesis

(2019) Ting-Li Han et al.   npj Biofilms and Microbiomes

The potential of respiration inhibition as a new approach to combat human fungal pathogens

(2019) Lucian Duvenage et al.   CURRENT GENETICS

Trk1-mediated potassium uptake contributes to cell-surface properties and virulence of Candida glabrata

(2019) Vicent Llopis-Torregrosa et al.   Scientific Reports

Invasive candidiasis

(2018) Peter G. Pappas et al.   Nature Reviews Disease Primers

Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species

(2018) José F. Muñoz et al.   Nature Communications

Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing

(2017) Vance L Albaugh et al.   JOURNAL OF NUTRITION

Increased plasma proline concentrations are associated with sarcopenia in the elderly

(2017) Kenji Toyoshima et al.   PLoS One

Put3 Positively Regulates Proline Utilization in Candida albicans

(2017) Walters Aji Tebung et al.   mSphere

Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses

(2017) James M. Phang   ANTIOXIDANTS & REDOX SIGNALING

Structural Biology of Proline Catabolic Enzymes

(2017) John J. Tanner   ANTIOXIDANTS & REDOX SIGNALING

Cryptococcosis

(2016) Eileen K. Maziarz et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Candidalysin is a fungal peptide toxin critical for mucosal infection

(2016) David L. Moyes et al.   NATURE

SOD Enzymes and Microbial Pathogens: Surviving the Oxidative Storm of Infection

(2016) Chynna N. Broxton et al.   PLoS Pathogens

Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate

(2015) Chad N. Hancock et al.   AMINO ACIDS

Proton pumping complex I increases growth yield in Candida utilis

(2015) Nicole Avéret et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort

(2015) J A Schmidt et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

An Effector Peptide Family Required for Drosophila Toll-Mediated Immunity

(2015) Alexa W. Clemmons et al.   PLoS Pathogens

Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways

(2015) Nora Grahl et al.   PLoS Pathogens

The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways

(2015) Michael Tscherner et al.   PLoS Pathogens

Connecting proline metabolism and signaling pathways in plant senescence

(2015) Lu Zhang et al.   Frontiers in Plant Science

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

(2014) R. P. Gazendam et al.   BLOOD

The Candida Pathogenic Species Complex

(2014) S. A. Turner et al.   Cold Spring Harbor Perspectives in Medicine

A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole

(2014) Benjamin D. Harrison et al.   PLOS BIOLOGY

Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

(2014) Anja Wartenberg et al.   PLoS Genetics

Sources of superoxide/H2O2 during mitochondrial proline oxidation

(2014) Renata L.S. Goncalves et al.   Redox Biology

Reactive Oxygen Species Homeostasis and Virulence of the Fungal Pathogen Cryptococcus neoformans Requires an Intact Proline Catabolism Pathway

(2013) I. R. Lee et al.   GENETICS

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

(2013) Michail S. Lionakis et al.   JOURNAL OF CLINICAL INVESTIGATION

Nanoliter Hemolymph Sampling and Analysis of Individual Adult Drosophila melanogaster

(2012) Sujeewa C. Piyankarage et al.   ANALYTICAL CHEMISTRY

Impact of Treatment Strategy on Outcomes in Patients with Candidemia and Other Forms of Invasive Candidiasis: A Patient-Level Quantitative Review of Randomized Trials

(2012) D. R. Andes et al.   CLINICAL INFECTIOUS DISEASES

The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast

(2012) Akira Nishimura et al.   FEBS LETTERS

Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in Saccharomyces cerevisiae

(2012) P. O. Ljungdahl et al.   GENETICS

Prolidase function in proline metabolism and its medical and biotechnological applications

(2012) R.L. Kitchener et al.   JOURNAL OF APPLIED MICROBIOLOGY

The histone acetyltransferase Hat1 facilitates DNA damage repair and morphogenesis inCandida albicans

(2012) Michael Tscherner et al.   MOLECULAR MICROBIOLOGY

The structure and allosteric regulation of mammalian glutamate dehydrogenase

(2011) Ming Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Candida Urinary Tract Infections—Diagnosis

(2011) Carol A. Kauffman et al.   CLINICAL INFECTIOUS DISEASES

Plasma Free Amino Acid Profiling of Five Types of Cancer Patients and Its Application for Early Detection

(2011) Yohei Miyagi et al.   PLoS One

Wild-Type Drosophila melanogaster as a Model Host to Analyze Nitrogen Source Dependent Virulence of Candida albicans

(2011) Monica M. Davis et al.   PLoS One

C- and N-catabolic utilization of tricarboxylic acid cycle-related amino acids by Scheffersomyces stipitis and other yeasts

(2011) Stefan Freese et al.   YEAST

Flocculation in Saccharomyces cerevisiae: a review

(2010) E.V. Soares   JOURNAL OF APPLIED MICROBIOLOGY

Organ-Specific Innate Immune Responses in a Mouse Model of Invasive Candidiasis

(2010) Michail S. Lionakis et al.   Journal of Innate Immunity

MMP- and TIMP-secretion by human cutaneous keratinocytes and fibroblasts – impact of coculture and hydration

(2010) Andrea A. Tandara et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Biological variation of free plasma amino acids in healthy individuals

(2009) Zoraida Corte et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Regulation and function of proline oxidase under nutrient stress

(2009) Jui Pandhare et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Characterization of a Helicobacter hepaticus putA Mutant Strain in Host Colonization and Oxidative Stress

(2008) N. Krishnan et al.   INFECTION AND IMMUNITY