Cx43 can form functional channels at the nuclear envelope and modulate gene expression in cardiac cells

Combinations of ivermectin with proteasome inhibitors induce synergistic lethality in multiple myeloma

(2023) Hongmei Luo et al.   CANCER LETTERS

Cx43‐mediated sorting of miRNAs into extracellular vesicles

(2022) Tania Martins‐Marques et al.   EMBO REPORTS

ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1

(2022) Xiaodan Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of nuclear envelope integrity as a possible initiating event in tauopathies

(2022) Marine Prissette et al.   Cell Reports

Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability

(2021) Maarten A.J. De Smet et al.   JOURNAL OF CLINICAL INVESTIGATION

Connecting different heart diseases through intercellular communication

(2021) Tania Martins-Marques   Biology Open

EHD1 Modulates Cx43 Gap Junction Remodeling Associated With Cardiac Diseases

(2020) Tania Martins-Marques et al.   CIRCULATION RESEARCH

An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression

(2020) Irina Epifantseva et al.   Biomolecules

Gap19, a Cx43 Hemichannel Inhibitor, Acts as a Gating Modifier That Decreases Main State Opening While Increasing Substate Gating

(2020) Alessio Lissoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes

(2020) Tania Martins-Marques et al.   Life Science Alliance

Wnt signaling regulates cytosolic translocation of Connexin 43

(2019) Xiaoming Hou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Biological Functions of Connexin43 Beyond Intercellular Communication

(2019) Tania Martins-Marques et al.   TRENDS IN CELL BIOLOGY

p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes

(2019) Audrey-Ann Dumont et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes

(2019) Alessio Lissoni et al.   CARDIOVASCULAR RESEARCH

Effect of shRNA Mediated Silencing of YB-1 Protein on the Expression of Matrix Collagenases in Malignant Melanoma Cell In Vitro

(2018) Wisam Ibrahim et al.   Cells

Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo

(2018) Maria Kotini et al.   Nature Communications

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

(2018) Rafael Almeida Paiva et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phosphorylation regulates connexin43/ZO-1 binding and release, an important step in gap junction turnover

(2017) Anastasia F. Thévenin et al.   MOLECULAR BIOLOGY OF THE CELL

Connexins and Disease

(2017) Mario Delmar et al.   Cold Spring Harbor Perspectives in Biology

Connexin 43 Hemichannels Regulate the Expression of Wound Healing-Associated Genes in Human Gingival Fibroblasts

(2017) Rana Tarzemany et al.   Scientific Reports

SharpViSu: integrated analysis and segmentation of super-resolution microscopy data

(2016) Leonid Andronov et al.   BIOINFORMATICS

Nuclear proton dynamics and interactions with calcium signaling

(2016) Alzbeta Hulikova et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Connexins in skeletal muscle development and disease

(2016) Peter A. Merrifield et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Next-Generation Connexin and Pannexin Cell Biology

(2016) Jessica L. Esseltine et al.   TRENDS IN CELL BIOLOGY

Dynamic changes in protein interaction between AKAP95 and Cx43 during cell cycle progression of A549 cells

(2016) Xiaoxuan Chen et al.   Scientific Reports

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

(2015) Tania Martins-Marques et al.   BIOCHEMICAL JOURNAL

Modular Detection of GFP-Labeled Proteins for Rapid Screening by Electron Microscopy in Cells and Organisms

(2015) Nicholas Ariotti et al.   DEVELOPMENTAL CELL

Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane

(2015) Rosemarie Ungricht et al.   JOURNAL OF CELL BIOLOGY

Accessorizing and anchoring the LINC complex for multifunctionality

(2015) Wakam Chang et al.   JOURNAL OF CELL BIOLOGY

Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis

(2015) Raquel Gago-Fuentes et al.   MOLECULAR & CELLULAR PROTEOMICS

Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

(2015) Tania Martins-Marques et al.   MOLECULAR & CELLULAR PROTEOMICS

Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype

(2015) Ana F. Branco et al.   PLoS One

Early Remodeling of Perinuclear Ca 2+ Stores and Nucleoplasmic Ca 2+ Signaling During the Development of Hypertrophy and Heart Failure

(2014) Senka Ljubojevic et al.   CIRCULATION

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

Directed evolution of APEX2 for electron microscopy and proximity labeling

(2014) Stephanie S Lam et al.   NATURE METHODS

Destination: inner nuclear membrane

(2013) Santharam S. Katta et al.   TRENDS IN CELL BIOLOGY

Receptor Tyrosine Kinases in the Nucleus

(2013) G. Carpenter et al.   Cold Spring Harbor Perspectives in Biology

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus

(2012) Kylie M. Wagstaff et al.   BIOCHEMICAL JOURNAL

Proliferation and skeletal myotube formation capability of C2C12 and H9c2 cells on isotropic and anisotropic electrospun nanofibrous PHB scaffolds

(2012) Leonardo Ricotti et al.   Biomedical Materials

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family

(2012) Ying-Nai Wang et al.   Cell and Bioscience

Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal

(2011) Steve Catarino et al.   BIOCHEMICAL JOURNAL

System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics

(2011) Nikolaj Zuleger et al.   JOURNAL OF CELL BIOLOGY

CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions

(2011) Amir Schajnovitz et al.   NATURE IMMUNOLOGY

Functional KV10.1 Channels Localize to the Inner Nuclear Membrane

(2011) Ye Chen et al.   PLoS One

Regulation of β-Catenin Nuclear Dynamics by GSK-3β Involves a LEF-1 Positive Feedback Loop

(2011) Cara Jamieson et al.   TRAFFIC

A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane

(2010) Yagmur Turgay et al.   EMBO JOURNAL

Ubiquitin-independent Proteasomal Degradation of Endoplasmic Reticulum-localized Connexin43 Mediated by CIP75

(2010) Vivian Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nuclear envelope at a glance

(2010) K. L. Wilson et al.   JOURNAL OF CELL SCIENCE

Connexin43 in cardiomyocyte mitochondria contributes to mitochondrial potassium uptake

(2009) Elisabet Miro-Casas et al.   CARDIOVASCULAR RESEARCH

The Nuclear Envelope as a Signaling Node in Development and Disease

(2009) William T. Dauer et al.   DEVELOPMENTAL CELL

Proteomic analysis of astroglial connexin43 silencing uncovers a cytoskeletal platform involved in process formation and migration

(2009) Stephan Olk et al.   GLIA

Limiting transport steps and novel interactions of Connexin-43 along the secretory pathway

(2009) Irina V. Majoul et al.   HISTOCHEMISTRY AND CELL BIOLOGY

ERp29 Restricts Connexin43 Oligomerization in the Endoplasmic Reticulum

(2009) Shamie Das et al.   MOLECULAR BIOLOGY OF THE CELL

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

(2009) S. Kosugi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nup358-RanGAP Complex Is Required for Efficient Importin α/β-dependent Nuclear Import

(2008) Saskia Hutten et al.   MOLECULAR BIOLOGY OF THE CELL

Monovalent, reduced-size quantum dots for imaging receptors on living cells

(2008) Mark Howarth et al.   NATURE METHODS

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

(2008) M. Landthaler et al.   RNA