Pharmacological and toxicological assessment of innovative self-assembled polymeric micelles as powders for insulin pulmonary delivery

Acute Ketamine Impairs Mitochondrial Function and Promotes Superoxide Dismutase Activity in the Rat Brain

(2015) Carlos Venâncio et al.   ANESTHESIA AND ANALGESIA

Solid state formulations composed by amphiphilic polymers for delivery of proteins: characterization and stability

(2015) Fernanda Andrade et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biological assessment of self-assembled polymeric micelles for pulmonary administration of insulin

(2015) Fernanda Andrade et al.   Nanomedicine-Nanotechnology Biology and Medicine

Aerodynamic and Electrostatic Properties of Model Dry Powder Aerosols: a Comprehensive Study of Formulation Factors

(2014) M. J. Telko et al.   AAPS PHARMSCITECH

Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies

(2014) Eleonore Fröhlich et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis of poly(N-isopropylacrylamide)-co-poly(phenylboronate ester) acrylate and study on their glucose-responsive behavior

(2014) Yuan Yao et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier

(2014) Jung Soo Suk et al.   JOURNAL OF CONTROLLED RELEASE

Pulmonary drug delivery by powder aerosols

(2014) Michael Yifei Yang et al.   JOURNAL OF CONTROLLED RELEASE

Good Cascade Impactor Practice (GCIP) and Considerations for “In-Use” Specifications

(2013) S. C. Nichols et al.   AAPS PHARMSCITECH

Nanoparticle diffusion in respiratory mucus from humans without lung disease

(2013) Benjamin S. Schuster et al.   BIOMATERIALS

Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles

(2013) Xiuying Li et al.   BIOMATERIALS

Inhaled biopharmaceutical drug development: nonclinical considerations and case studies

(2013) Mary C. McElroy et al.   INHALATION TOXICOLOGY

Comparative study of Pluronic® F127-modified liposomes and chitosan-modified liposomes for mucus penetration and oral absorption of cyclosporine A in rats

(2013) Dan Chen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Inhaled proteins: Challenges and perspectives

(2013) Flore Depreter et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Fabrication of inhalable spore like pharmaceutical particles for deep lung deposition

(2012) Zhi-Gang Shen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In Vitro and In Vivo Characterisation of PEG-Lipid-Based Micellar Complexes of Salmon Calcitonin for Pulmonary Delivery

(2012) Leonie Baginski et al.   PHARMACEUTICAL RESEARCH

Influence of lactose carrier particle size on the aerosol performance of budesonide from a dry powder inhaler

(2012) Waseem Kaialy et al.   POWDER TECHNOLOGY

Biodegradable Nanoparticles Composed Entirely of Safe Materials that Rapidly Penetrate Human Mucus

(2011) Ming Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism underlying insulin uptake in alveolar epithelial cell line RLE-6TN

(2011) Keisuke Oda et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microencapsulated chitosan nanoparticles for pulmonary protein delivery: In vivo evaluation of insulin-loaded formulations

(2011) S. Al-Qadi et al.   JOURNAL OF CONTROLLED RELEASE

A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles

(2011) Olcay Mert et al.   JOURNAL OF CONTROLLED RELEASE

Dry Powder Inhaler Device Influence on Carrier Particle Performance

(2011) Martin J. Donovan et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction

(2010) Juan W. Valle et al.   INVESTIGATIONAL NEW DRUGS

Nanocarriers for pulmonary administration of peptides and therapeutic proteins

(2010) Fernanda Andrade et al.   Nanomedicine

Dry powder measles vaccine: Particle deposition, virus replication, and immune response in cotton rats following inhalation

(2010) Kevin O. Kisich et al.   VACCINE

Effect of Sugars, Surfactant, and Tangential Flow Filtration on the Freeze-Drying of Poly(lactic acid) Nanoparticles

(2009) Samuli Hirsjärvi et al.   AAPS PHARMSCITECH

The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles

(2009) Jung Soo Suk et al.   BIOMATERIALS

Pharmacokinetics and linear exposure of AFRESA™ compared with the subcutaneous injection of regular human insulin

(2009) K. Rave et al.   DIABETES OBESITY & METABOLISM

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

(2008) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

Addressing the PEG Mucoadhesivity Paradox to Engineer Nanoparticles that “Slip” through the Human Mucus Barrier

(2008) Ying-Ying Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-Year Pulmonary Safety and Efficacy of Inhaled Human Insulin (Exubera) in Adult Patients With Type 2 Diabetes

(2008) J. Rosenstock et al.   DIABETES CARE

In Vitro/In Vivo Comparisons in Pulmonary Drug Delivery

(2008) Stephen P. Newman et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers

(2008) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: In vivo deposition and hypoglycaemic activity after delivery to rat lungs

(2008) Francesca Ungaro et al.   JOURNAL OF CONTROLLED RELEASE

Drug delivery: Stealth particles give mucus the slip

(2008) Yen Cu et al.   NATURE MATERIALS