Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay

Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion

(2022) Debyani Chakravarty et al.   JOURNAL OF CLINICAL ONCOLOGY

Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients

(2022) Ozge Ceyhan-Birsoy et al.   Genome Medicine

Paired Tumor-Germline Testing as a Driver in Better Cancer Care

(2022) John W. Henson   JAMA Network Open

Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors

(2022) Amin H. Nassar et al.   CANCER CELL

Accurate and efficient detection of gene fusions from RNA sequencing data

(2021) Sebastian Uhrig et al.   GENOME RESEARCH

Time Trends in Receipt of Germline Genetic Testing and Results for Women Diagnosed With Breast Cancer or Ovarian Cancer, 2012-2019

(2021) Allison W. Kurian et al.   JOURNAL OF CLINICAL ONCOLOGY

The evolving landscape of biomarker testing for non-small cell lung cancer in Europe

(2021) Keith M. Kerr et al.   LUNG CANCER

628P Universal germline testing of prostate cancer patients: Are genetic testing guidelines an aid or an impediment to precision therapy?

(2021) M.K. Hardwick et al.   ANNALS OF ONCOLOGY

Molecular testing in stage I–III non-small cell lung cancer: approaches and challenges

(2021) Charu Aggarwal et al.   LUNG CANCER

Association Between Medicare's National Coverage Determination and Utilization of Next-Generation Sequencing

(2021) Daniel M. Sheinson et al.   JCO Oncology Practice

Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project

(2021) D.M. Vega et al.   ANNALS OF ONCOLOGY

NGS testing patterns in advanced non-small cell lung cancer (aNSCLC) and metastatic breast cancer (mBC): OneOncology (OO) sites compared to Flatiron Health Nationwide (NAT).

(2021) Ari M. Vanderwalde et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular profiling for precision cancer therapies

(2020) Eoghan R. Malone et al.   Genome Medicine

A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients

(2020) Kai Zheng et al.   Journal of Translational Medicine

Transcriptomic silencing as a potential mechanism of treatment resistance

(2020) Jacob J. Adashek et al.   JCI Insight

Next Generation Sequencing for Gene Fusion Analysis in Lung Cancer: A Literature Review

(2020) Rossella Bruno et al.   Diagnostics

Diagnosis of fusion genes using targeted RNA sequencing

(2019) Erin E. Heyer et al.   Nature Communications

Germline-Focused Analysis of Tumour-Only Sequencing: Recommendations from the ESMO Precision Medicine Working Group

(2019) D Mandelker et al.   ANNALS OF ONCOLOGY

The current state of molecular testing in the treatment of patients with solid tumors, 2019

(2019) Wafik S. El‐Deiry et al.   CA-A CANCER JOURNAL FOR CLINICIANS

High yield of RNA sequencing for targetable kinase fusions in lung adenocarcinomas with no driver alteration detected by DNA sequencing and low tumor mutation burden

(2019) Ryma Benayed et al.   CLINICAL CANCER RESEARCH

Genetic Testing and Results in a Population-Based Cohort of Breast Cancer Patients and Ovarian Cancer Patients

(2019) Allison W. Kurian et al.   JOURNAL OF CLINICAL ONCOLOGY

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

(2019) James P. Solomon et al.   MODERN PATHOLOGY

Integrated genomic profiling expands clinical options for patients with cancer

(2019) Nike Beaubier et al.   NATURE BIOTECHNOLOGY

Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer

(2018) Yuri Choi et al.   BRITISH JOURNAL OF CANCER

Real-World Evidence In Support Of Precision Medicine: Clinico-Genomic Cancer Data As A Case Study

(2018) Vineeta Agarwala et al.   HEALTH AFFAIRS

Value-based genomics

(2018) Jun Gong et al.   Oncotarget

NTRK fusion-positive cancers and TRK inhibitor therapy

(2018) Emiliano Cocco et al.   Nature Reviews Clinical Oncology

Molecular and Computational Methods for the Detection of Microsatellite Instability in Cancer

(2018) Laura G. Baudrin et al.   Frontiers in Oncology

Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer

(2017) Marilyn M. Li et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits

(2017) Wanlong Ma et al.   Molecular Diagnosis & Therapy

Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study

(2016) Jennifer J. Wheler et al.   CANCER RESEARCH

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

(2016) Raphael Bueno et al.   NATURE GENETICS

The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine

(2016) Andrea Garofalo et al.   Genome Medicine

Broad, Hybrid Capture-Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches

(2015) A. Drilon et al.   CLINICAL CANCER RESEARCH

Personalized genomic analyses for cancer mutation discovery and interpretation

(2015) Siân Jones et al.   Science Translational Medicine

Achieving high-sensitivity for clinical applications using augmented exome sequencing

(2015) Anil Patwardhan et al.   Genome Medicine

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS