Effects of a High-Fat Diet and Docosahexaenoic Acid during Pregnancy on Fatty Acid Composition in the Fetal Livers of Mice

Maternal polyunsaturated fatty acid concentrations during pregnancy and childhood liver fat accumulation

(2022) Rama J. Wahab et al.   CLINICAL NUTRITION

Maternal Fatty Acid Metabolism in Pregnancy and Its Consequences in the Feto-Placental Development

(2022) Asim K. Duttaroy et al.   Frontiers in Physiology

Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity

(2022) Anika K. Anam et al.   Molecular Metabolism

Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese mice

(2022) Haoya Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity downregulates lipid metabolism genes in first trimester placenta

(2022) Aisha Rasool et al.   Scientific Reports

Liver Enzymes Correlate With Metabolic Syndrome, Inflammation, and Endothelial Dysfunction in Prepubertal Children With Obesity

(2021) Rosario Valle-Martos et al.   Frontiers in Pediatrics

Placental function in maternal obesity

(2020) Amy C. Kelly et al.   CLINICAL SCIENCE

Peroxisomal oxidation of erucic acid suppresses mitochondrial fatty acid oxidation by stimulating malonyl-CoA formation in the rat liver

(2020) Xiaocui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The offspring from rats fed a fatty diet display impairments in the activation of liver peroxisome proliferator activated receptor alpha and features of fatty liver disease

(2020) Florencia Heinecke et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Maternal High Linoleic Acid Alters Placental Fatty Acid Composition

(2020) Nirajan Shrestha et al.   Nutrients

Monounsaturated Fatty Acids in Obesity-Related Inflammation

(2020) Gaetan Ravaut et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Altered materno-fetal transfer of 13C-polyunsaturated fatty acids in obese pregnant women

(2019) A. Gázquez et al.   CLINICAL NUTRITION

Plasma fatty acid patterns during pregnancy and child's growth, body composition, and cardiometabolic health: The Generation R Study

(2018) Trudy Voortman et al.   CLINICAL NUTRITION

Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation

(2018) Sobha Puppala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Postprandial Triglycerides Predict Newborn Fat More Strongly than Glucose in Women with Obesity in Early Pregnancy

(2018) Linda A. Barbour et al.   Obesity

Sex and gender differences in developmental programming of metabolism

(2018) Laura Dearden et al.   Molecular Metabolism

Reduction of high-fat diet-induced liver pro-inflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: Involvement of resolvins RvE1/2 and RvD1/2

(2018) F. Echeverría et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary Unsaturated Fatty Acids Modulate Maternal Dyslipidemia-Induced DNA Methylation and Histone Acetylation in Placenta and Fetal Liver in Rats

(2018) Breetha Ramaiyan et al.   LIPIDS

Concentrations of docosahexaenoic acid are reduced in maternal liver, adipose, and heart in rats fed high-fat diets without docosahexaenoic acid throughout pregnancy

(2018) Daniel M. Lamontagne-Kam et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Effect of Maternal Obesity on Placental Lipid Metabolism

(2017) Virtu Calabuig-Navarro et al.   ENDOCRINOLOGY

Nonalcoholic fatty liver disease in adolescents and young adults: The next frontier in the epidemic

(2017) Iliana Doycheva et al.   HEPATOLOGY

Nonalcoholic Fatty Liver Disease in Children

(2017) Praveen Kumar Conjeevaram Selvakumar et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Maternal plasma PUFA concentrations during pregnancy and childhood adiposity: the Generation R Study

(2016) Aleksandra Jelena Vidakovic et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Metabolic fate of docosahexaenoic acid (DHA; 22:6n-3) in human cells: direct retroconversion of DHA to eicosapentaenoic acid (20:5n-3) dominates over elongation to tetracosahexaenoic acid (24:6n-3)

(2016) Hui Gyu Park et al.   FEBS LETTERS

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

Maternal saturated-fat-rich diet promotes leptin resistance in fetal liver lipid catabolism and programs lipid homeostasis impairments in the liver of rat offspring

(2016) María Belén Mazzucco et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women

(2016) Susanne Lager et al.   PLACENTA

Liver Fatty Acid Composition and Inflammation in Mice Fed with High-Carbohydrate Diet or High-Fat Diet

(2016) Lorena da Silva-Santi et al.   Nutrients

Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy

(2015) Paula Díaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice

(2015) Liping Qiao et al.   DIABETES

Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning

(2015) Limor Shomonov-Wagner et al.   Lipids in Health and Disease

Transcriptional regulation of hepatic lipogenesis

(2015) Yuhui Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice

(2014) Joao A. G. Duarte et al.   JOURNAL OF LIPID RESEARCH

N-3long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-α upregulation and NF-κB DNA binding abrogation

(2014) Gladys Tapia et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes

(2014) Rachel D. Wilson et al.   Pharmacological Reports

Modulation of Fatty Acid Transport and Metabolism by Maternal Obesity in the Human Full-Term Placenta1

(2012) Evemie Dubé et al.   BIOLOGY OF REPRODUCTION

The Influence of Maternal Body Mass Index on Infant Adiposity and Hepatic Lipid Content

(2011) Neena Modi et al.   PEDIATRIC RESEARCH

Maternal High Fat Diet Is Associated with Decreased Plasma n–3 Fatty Acids and Fetal Hepatic Apoptosis in Nonhuman Primates

(2011) Wilmon F. Grant et al.   PLoS One

Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice

(2009) Makoto Miyazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

5-lipoxygenase deficiency reduces hepatic inflammation and tumor necrosis factor α-induced hepatocyte damage in hyperlipidemia-prone ApoE-null mice

(2009) Marcos Martínez-Clemente et al.   HEPATOLOGY

Decreased Liver Fatty Acid Δ-6 and Δ-5 Desaturase Activity in Obese Patients

(2009) Julia Araya et al.   Obesity