Geraniol Inhibits Cell Growth and Promotes Caspase-Dependent Apoptosis in Nasopharyngeal Cancer C666-1 Cells via Inhibiting PI3K/Akt/mTOR Signaling Pathway

Ophiopogonin B induces reactive oxygen species‑dependent apoptosis through the Hippo pathway in nasopharyngeal carcinoma

(2021) Wenhui Dong et al.   Molecular Medicine Reports

Correlation of the AKT/mTOR signaling pathway with the clinicopathological features and prognosis of nasopharyngeal carcinoma

(2021) Yan Wang et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Genipin Induces Autophagy and Suppresses Cell Growth of Oral Squamous Cell Carcinoma via PI3K/AKT/MTOR Pathway

(2020) MingBo Wei et al.   Drug Design Development and Therapy

Celastrol Suppresses Glioma Vasculogenic Mimicry Formation and Angiogenesis by Blocking the PI3K/Akt/mTOR Signaling Pathway

(2020) Yingjun Zhu et al.   Frontiers in Pharmacology

Geraniol activates Nrf-2/HO-1 signaling pathway mediating protection against oxidative stress-induced apoptosis in hepatic ischemia-reperfusion injury

(2020) Soad Z. El-Emam et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma

(2020) Oluwaseun Adebayo Bamodu et al.   Cells

Geraniol ameliorates diabetic nephropathy via interference with miRNA-21/PTEN/Akt/mTORC1 pathway in rats

(2020) Yasmin Ahmed Mohamed El-Said et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

PI3K/AKT/mTOR Signaling Pathway in Breast Cancer: From Molecular Landscape to Clinical Aspects

(2020) Daniela Miricescu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nasopharyngeal carcinoma

(2019) Yu-Pei Chen et al.   LANCET

Thymoquinone and geraniol alleviate cisplatin-induced neurotoxicity in rats through downregulating the p38 MAPK/STAT-1 pathway and oxidative stress

(2019) Mohamed A. Kandeil et al.   LIFE SCIENCES

Induction chemotherapy improves efficacy

(2019) Peter Sidaway   Nature Reviews Clinical Oncology

Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma

(2019) Yuan Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase

(2019) Jingxian Liu et al.   Cancer Cell International

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pharmacological Properties of Geraniol – A Review

(2018) Yu Lei et al.   PLANTA MEDICA

Effect of geraniol on rat cardiomyocytes and its potential use as a cardioprotective natural compound

(2017) R Crespo et al.   LIFE SCIENCES

Role of the tumor microenvironment in regulating apoptosis and cancer progression

(2016) Katherine Yaacoub et al.   CANCER LETTERS

Roles of Reactive Oxygen Species in Anticancer Therapy withSalvia miltiorrhiza Bunge

(2016) Yu-Chiang Hung et al.   Oxidative Medicine and Cellular Longevity

Protective effect of geraniol inhibits inflammatory response, oxidative stress and apoptosis in traumatic injury of the spinal cord through modulation of NF-κB and p38 MAPK

(2016) Jiansheng Wang et al.   Experimental and Therapeutic Medicine

Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway

(2016) Xiao-Min Zhou et al.   Oncotarget

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

(2015) Isaac S. Harris et al.   CANCER CELL

Geraniol ameliorates TNBS-induced colitis: Involvement of Wnt/β-catenin, p38MAPK, NFκB, and PPARγ signaling pathways

(2015) Ayman A. Soubh et al.   LIFE SCIENCES

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity

(2015) YEE-LIN VOON et al.   ONCOLOGY REPORTS

Activation of Akt/mTOR Pathway Is Associated with Poor Prognosis of Nasopharyngeal Carcinoma

(2014) Weiyuan Wang et al.   PLoS One

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

A potential antitumor agent, (6-amino-1-methyl-5-nitrosouracilato-N3)-triphenylphosphine-gold(I): Structural studies and in vivo biological effects against experimental glioma

(2013) Nuria A. Illán-Cabeza et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway

(2010) Songgang Li et al.   CANCER LETTERS

Current treatment options for recurrent nasopharyngeal cancer

(2010) Carlos Suárez et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Intracellular GSH Depletion Triggered Mitochondrial Bax Translocation to Accomplish Resveratrol-Induced Apoptosis in the U937 Cell Line

(2010) P. Guha et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A glycosylphosphatidylinositol analogue reduced prion-derived peptide mediated activation of cytoplasmic phospholipase A2, synapse degeneration and neuronal death

(2010) Clive Bate et al.   NEUROPHARMACOLOGY

Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas

(2010) Ramarao Malla et al.   PLoS One

Topotecan Triggers Apoptosis in p53-Deficient Cells by Forcing Degradation of XIAP and Survivin Thereby Activating Caspase-3-Mediated Bid Cleavage

(2009) M. T. Tomicic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS