Genotoxic investigation of a thiazolidinedione PPARγ agonist using thein vitromicronucleus test and thein vivohomozygotization assay

Assessment of In Vivo and In Vitro Genotoxicity of Glibenclamide in Eukaryotic Cells

(2015) Juliane Rocha de Sant’Anna et al.   PLoS One

Gene homozygosis and mitotic recombination induced by camptothecin and irinotecan in Aspergillus nidulans diploid cells

(2014) GIOVANA N.M. ESQUISSATO et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Inhibition of Cancer Cell Proliferation by PPARγ Is Mediated by a Metabolic Switch that Increases Reactive Oxygen Species Levels

(2014) Nishi Srivastava et al.   Cell Metabolism

Pioglitazone has a dubious bladder cancer risk but an undoubted cardiovascular benefit

(2014) R. E. J. Ryder   DIABETIC MEDICINE

A Review on Thiazolidinediones and Bladder Cancer in Human Studies

(2014) Chin-Hsiao Tseng   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Thiazolidinediones and cancer: results of a meta-analysis of randomized clinical trials

(2013) Matteo Monami et al.   ACTA DIABETOLOGICA

Inhibition of Lung Tumorigenesis by Metformin Is Associated with Decreased Plasma IGF-I and Diminished Receptor Tyrosine Kinase Signaling

(2013) B. J. Quinn et al.   Cancer Prevention Research

Metformin's performance in in vitro and in vivo genetic toxicology studies

(2013) Juliane R Sant'Anna et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Repair of Strand Breaks by Homologous Recombination

(2013) M. Jasin et al.   Cold Spring Harbor Perspectives in Biology

Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation

(2012) Arron Sikka et al.   CELL CYCLE

Mitotic recombination of chromosome arm 17q as a cause of loss of heterozygosity of NF1 in neurofibromatosis type 1-associated glomus tumors

(2012) Douglas R. Stewart et al.   GENES CHROMOSOMES & CANCER

Evaluation of vitamin B12 effects on DNA damage induced by pioglitazone

(2012) Karem Alzoubi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance

(2011) Micheline Kirsch-Volders et al.   ARCHIVES OF TOXICOLOGY

Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

(2011) D. Iliopoulos et al.   CANCER RESEARCH

Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone: Interim report of a longitudinal cohort study

(2011) J. D. Lewis et al.   DIABETES CARE

The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact

(2011) Esther Phielix et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs

(2010) Toshikatsu Okumura   JOURNAL OF GASTROENTEROLOGY

Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas

(2010) K D Hadfield et al.   ONCOGENE

Evaluation of the genotoxic potential and acute oral toxicity of standardized extract of Andrographis paniculata (KalmCold™)

(2009) C.V. Chandrasekaran et al.   FOOD AND CHEMICAL TOXICOLOGY

A novel role for vitamin B12: Cobalamins are intracellular antioxidants in vitro

(2009) Catherine S. Birch et al.   FREE RADICAL BIOLOGY AND MEDICINE

Assessment of genotoxicity in rats treated with the antidiabetic agent, pioglitazone

(2008) Abdulkerim Bedir et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test

(2008) E. Lorge et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS