Comprehensive Analysis of METTLs (METTL1/13/18/21A/23/25/2A/2B/5/6/9) and Associated mRNA Risk Signature in Hepatocellular Carcinoma

Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma

(2022) Yuanjun Lu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Preneoplastic lesions in the liver: Molecular insights and relevance for clinical practice

(2022) Elvire Desjonqueres et al.   LIVER INTERNATIONAL

Eliminating METTL1 ‐mediated accumulation of PMN‐MDSCs prevents HCC recurrence after radiofrequency ablation

(2022) Xuezhen Zeng et al.   HEPATOLOGY

USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma

(2022) Zhen Ning et al.   Nature Communications

Sofosbuvir induces gene expression for promoting cell proliferation and migration of hepatocellular carcinoma cells

(2022) Wei-Lun Tsai et al.   Aging-US

Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease

(2022) Naoto Fujiwara et al.   Science Translational Medicine

MEX3A promotes the malignant progression of ovarian cancer by regulating intron retention in TIMELESS

(2022) Fangfang Li et al.   Cell Death & Disease

Targeting tumour-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy

(2022) Haining Liu et al.   GUT

Integrative analysis of m3C associated genes reveals METTL2A as a potential oncogene in breast Cancer

(2022) Shuai Wang et al.   Journal of Translational Medicine

Dysregulation of EZH2/miR-138-5p Axis Contributes to Radiosensitivity in Hepatocellular Carcinoma Cell by Downregulating Hypoxia-Inducible Factor 1 Alpha (HIF-1α)

(2022) Bing Bai et al.   Oxidative Medicine and Cellular Longevity

Knockdown of METTL5 inhibits the Myc pathway to downregulate PD-L1 expression and inhibits immune escape of hepatocellular carcinoma cells

(2022) Wenjie Xu et al.   JOURNAL OF CHEMOTHERAPY

Silencing CDCA8 Suppresses Hepatocellular Carcinoma Growth and Stemness via Restoration of ATF3 Tumor Suppressor and Inactivation of AKT/β–Catenin Signaling

(2021) Taewon Jeon et al.   Cancers

The rs599839 A>G Variant Disentangles Cardiovascular Risk and Hepatocellular Carcinoma in NAFLD Patients

(2021) Marica Meroni et al.   Cancers

The Role of Tumor Microenvironment in Cancer Metastasis: Molecular Mechanisms and Therapeutic Opportunities

(2021) Christiana M. Neophytou et al.   Cancers

METTL21B is a prognostic biomarker and potential therapeutic target in low-grade gliomas

(2021) Xin Shu et al.   Aging-US

Immune signature-based hepatocellular carcinoma subtypes may provide novel insights into therapy and prognosis predictions

(2021) Qiuxian Zheng et al.   Cancer Cell International

NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options

(2021) Friedrich Foerster et al.   JOURNAL OF HEPATOLOGY

METTL1/WDR4-mediated m7G tRNA modifications and m7G codon usage promote mRNA translation and lung cancer progression

(2021) Jieyi Ma et al.   MOLECULAR THERAPY

Cancer stem cells in hepatocellular carcinoma — from origin to clinical implications

(2021) Terence Kin-Wah Lee et al.   Nature Reviews Gastroenterology & Hepatology

A comprehensive review of m6A/m6Am RNA methyltransferase structures

(2021) Stephanie Oerum et al.   NUCLEIC ACIDS RESEARCH

TP53 Mutation Related and Directly Regulated lncRNA Prognosis Markers in Hepatocellular Carcinoma

(2021) Xiulei Zhang et al.   OncoTargets and Therapy

PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3

(2021) Dawei Chen et al.   Cell Death & Disease

METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth

(2021) Mengyue Lv et al.   Protein & Cell

Extracellular Matrices and Cancer-Associated Fibroblasts: Targets for Cancer Diagnosis and Therapy?

(2021) Ismahane Belhabib et al.   Cancers

Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma

(2021) Tian-Hao Li et al.   Frontiers in Oncology

The effect of the TP53 and RB1 mutations on the survival of hepatocellular carcinoma patients with different racial backgrounds

(2021) Xiaohui Duan et al.   Journal of Gastrointestinal Oncology

Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules

(2021) Amina Bolatkan et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Immunotherapies for hepatocellular carcinoma

(2021) Josep M. Llovet et al.   Nature Reviews Clinical Oncology

Role of Calcium Signaling Pathway-Related Gene Regulatory Networks in Ischemic Stroke Based on Multiple WGCNA and Single-Cell Analysis

(2021) Weiwei Lin et al.   Oxidative Medicine and Cellular Longevity

Methyltransferase-like protein 11A promotes migration of cervical cancer cells via up-regulating ELK3

(2021) Jinling Zhang et al.   PHARMACOLOGICAL RESEARCH

METTL1‐m 7 G‐EGFR/EFEMP1 axis promotes the bladder cancer development

(2021) Xiaoling Ying et al.   Clinical and Translational Medicine

METTL1 promotes hepatocarcinogenesis via m 7 G tRNA modification‐dependent translation control

(2021) Zhihang Chen et al.   Clinical and Translational Medicine

BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update

(2021) Maria Reig et al.   JOURNAL OF HEPATOLOGY

Non-metabolic role of UCK2 links EGFR-AKT pathway activation to metastasis enhancement in hepatocellular carcinoma

(2020) Jie Cai et al.   Oncogenesis

Genomic Analysis of Vascular Invasion in HCC Reveals Molecular Drivers and Predictive Biomarkers

(2020) Maya S. Krishnan et al.   HEPATOLOGY

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Disease Burden of Hepatocellular Carcinoma: A Global Perspective

(2019) Mehmet Sayiner et al.   DIGESTIVE DISEASES AND SCIENCES

HN1L-mediated transcriptional axis AP-2γ/METTL13/TCF3-ZEB1 drives tumor growth and metastasis in hepatocellular carcinoma

(2019) Lei Li et al.   CELL DEATH AND DIFFERENTIATION

The role of m6A RNA methylation in cancer

(2019) Ting Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma

(2019) Man Liu et al.   GUT

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Natural killer cells involved in tumour immune escape of hepatocellular carcinomar

(2019) Chen Han et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities

(2019) Chen Lu et al.   Molecular Cancer

GeneMANIA update 2018

(2018) Max Franz et al.   NUCLEIC ACIDS RESEARCH

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

(2017) Guoying Zhou et al.   GASTROENTEROLOGY

pRRophetic: An R Package for Prediction of Clinical Chemotherapeutic Response from Tumor Gene Expression Levels

(2014) Paul Geeleher et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Uncovering the Human Methyltransferasome

(2010) Tanya C. Petrossian et al.   MOLECULAR & CELLULAR PROTEOMICS

Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells

(2008) Monika Szeliga et al.   GLIA