Advances in screening assays for identifying cholinesterase ligands

Affinity Selection Mass Spectrometry (AS-MS) as a Tool for Prospecting Target Ligands

(2023) Fernando Almeida et al.   Brazilian Journal of Analytical Chemistry

Profile comparison and valorization of Tunisian Salvia aegyptiaca and S. verbenaca aerial part extracts via hyphenated high‐performance thin‐layer chromatography

(2022) Amira Reguigui et al.   JOURNAL OF CHROMATOGRAPHY A

Development of nano Bio LC columns for the search of acethylcholinesterase molecular targets

(2022) Claire André et al.   JOURNAL OF SEPARATION SCIENCE

A Comprehensive 2D-LC/MS Online Platform for Screening of Acetylcholinesterase Inhibitors

(2022) Claudia Seidl et al.   Frontiers in Molecular Biosciences

Anti-Alzheimer's disease active components screened out and identified from Hedyotis diffusa combining bioaffinity ultrafiltration LC-MS with acetylcholinesterase

(2022) Jing Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Simultaneous screening, identification, quantitation, and activity evaluation of six acetylcholinesterase (AChE) inhibitors in Coptidis Rhizoma by online UPLC-DAD coupled with AChE biochemical detection

(2022) Jing-ling Tan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside

(2022) Mahmoud Fahmi Elsebai et al.   Scientific Reports

Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein–protein interaction inhibitor

(2022) Jing Gu et al.   Nature Communications

Role of natural products for the treatment of Alzheimer's disease

(2021) Tayebeh Noori et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Affinity selection–mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products

(2021) Ruth N. Muchiri et al.   JOURNAL OF MASS SPECTROMETRY

Magnetic particles for enzyme immobilization: A versatile support for ligand screening

(2021) Isabela Abreu Trindade Ximenes et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

UHPLC With On-Line Coupled Biochemical Detection for High Throughput Screening of Acetylcholinesterase Inhibitors in Coptidis Rhizoma and Cortex Phellodendri

(2021) Jingling Tan et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Probing the acetylcholinesterase inhibitory activity of a novel Ru(II) polypyridyl complex and the supramolecular interaction by (STD)-NMR

(2021) Marlon P. Almeida et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study

(2020) Carolina S. Marques et al.   BIOORGANIC CHEMISTRY

Miniaturized technologies for high-throughput drug screening enzymatic assays and diagnostics – A review

(2020) Sarah A.P. Pereira et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Recent advances in screening active components from natural products based on bioaffinity techniques

(2020) Xiaofang Hou et al.   Acta Pharmaceutica Sinica B

Exploring new targets and chemical space with affinity selection-mass spectrometry

(2020) Renaud Prudent et al.   Nature Reviews Chemistry

Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer’s disease

(2019) Umesh Chandra Dash et al.   BIOORGANIC CHEMISTRY

Comparative biophysical characterization: A screening tool for acetylcholinesterase inhibitors

(2019) Devashree N. Patil et al.   PLoS One

A novel on-flow mass spectrometry-based dual enzyme assay

(2019) Claudia Seidl et al.   ANALYTICA CHIMICA ACTA

A Library Screening Strategy Combining the Concepts of MS Binding Assays and Affinity Selection Mass Spectrometry

(2019) Jürgen Gabriel et al.   Frontiers in Chemistry

Solid-Supported Proteins in the Liquid Chromatography Domain to Probe Ligand-Target Interactions

(2019) Marcela Cristina de Moraes et al.   Frontiers in Chemistry

Cholinesterases and the fine line between poison and remedy

(2018) Carey N. Pope et al.   BIOCHEMICAL PHARMACOLOGY

Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors

(2018) Talita P.C. Chierrito et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Online screening of acetylcholinesterase inhibitors in natural products using monolith-based immobilized capillary enzyme reactors combined with liquid chromatography-mass spectrometry

(2018) Lvhuan Wang et al.   JOURNAL OF CHROMATOGRAPHY A

Characterization of the interactions between coumarin-derivatives and acetylcholinesterase: Examination by NMR and docking simulations

(2018) Nazish U. Tanoli et al.   JOURNAL OF MOLECULAR MODELING

Rapid ligand fishing for identification of acetylcholinesterase-binding peptides in snake venom reveals new properties of dendrotoxins

(2018) Kenia Lourenço Vanzolini et al.   TOXICON

Determination of affinity and efficacy of acetylcholinesterase inhibitors using isothermal titration calorimetry

(2016) Piotr Draczkowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

New cholinesterase inhibitors for Alzheimer’s disease: Structure Activity Studies (SARs) and molecular docking of isoquinolone and azepanone derivatives

(2016) Patrícia Bacalhau et al.   BIOORGANIC CHEMISTRY

Ligand Fishing: A Remarkable Strategy for Discovering Bioactive Compounds from Complex Mixture of Natural Products

(2016) Rongjie Zhuo et al.   MOLECULES

NMR in drug discovery: A practical guide to identification and validation of ligands interacting with biological macromolecules

(2016) Alvar D. Gossert et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Acetylcholinesterase immobilized on modified magnetic beads as a tool for screening a compound library

(2015) Kenia L. Vanzolini et al.   MICROCHIMICA ACTA

Evaluation of binding competition and group epitopes of acetylcholinesterase inhibitors by STD NMR, Tr-NOESY, DOSY and molecular docking: an old approach but new findings

(2015) Nazish U. Tanoli et al.   MedChemComm

Optimal detection of cholinesterase activity in biological samples: Modifications to the standard Ellman’s assay

(2014) Dominika Dingova et al.   ANALYTICAL BIOCHEMISTRY

Molecular Recognition of Rosmarinic Acid fromSalvia sclareoidesExtracts by Acetylcholinesterase: A New Binding Site Detected by NMR Spectroscopy

(2013) Filipa Marcelo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Immobilized cholinesterases capillary reactors on-flow screening of selective inhibitors

(2013) Adriana Ferreira Lopes Vilela et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Acetylcholinesterase Immobilized Capillary Reactors–Tandem Mass Spectrometry: An On-Flow Tool for Ligand Screening

(2013) Kenia L. Vanzolini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Improved Thin-layer Chromatography Bioautographic Assay for the Detection of Actylcholinesterase Inhibitors in Plants

(2011) Zhong-Duo Yang et al.   PHYTOCHEMICAL ANALYSIS

Ligand-Receptor Binding Affinities from Saturation Transfer Difference (STD) NMR Spectroscopy: The Binding Isotherm of STD Initial Growth Rates

(2010) Jesús Angulo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bioautography detection in thin-layer chromatography

(2010) Irena M. Choma et al.   JOURNAL OF CHROMATOGRAPHY A

Spin-Lattice Relaxation Time in Drug Discovery and Design

(2009) Jose Figueroa-Villar et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Highly efficient, selective and sensitive molecular screening of acetylcholinesterase inhibitors of natural origin by solid-phase extraction-liquid chromatography/electrospray ionisation-octopole-orthogonal acceleration time-of-flight-mass spectrometry and novel thin-layer chromatography-based bioautography

(2009) Tomasz Mroczek   JOURNAL OF CHROMATOGRAPHY A

In vitro screening assays to identify natural or synthetic acetylcholinesterase inhibitors: Thin layer chromatography versus microplate methods

(2007) Saviana Di Giovanni et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES