Facile synthesis of 3-(pyrazol-1-yl) succinimides from Ag 2 CO 3 -catalyzed aza-Michael addition of pyrazoles to maleimides

4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments

(2023) Mahmoud A. Ragab et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Regio- and Stereoselective Switchable Synthesis of (E)- and (Z)-N-Carbonylvinylated Pyrazoles

(2023) Xue Zhang et al.   MOLECULES

Ag2CO3 catalyzed aza-michael addition of pyrazoles to α, β-unsaturated carbonyl compounds: A new access to N-alkylated pyrazole derivatives

(2023) Xue Zhang et al.   TETRAHEDRON

New pyrazole-tetrazole hybrid compounds as potent α-amylase and non-enzymatic glycation inhibitors

(2022) Ahlam Oulous et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of novel N-acylpyrazoles as potent and selective thrombin inhibitors

(2022) Kevin M. Short et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids

(2021) Ashraf S. Hassan et al.   ACS Omega

Facile Construction of Troponoid Derivatives Incorporating Imidazolin-2-one Moieties

(2020) Jing Yu et al.   SYNTHESIS-STUTTGART

Catalyst free cyclocondensation of β-ethylthio-β-indolyl-α, β-unsaturated ketones with hydrazines: Efficient synthesis of 3-pyrazolyl indoles

(2020) Hai-Feng Yu et al.   SYNTHETIC COMMUNICATIONS

A Randomized, Double‐Blind, Placebo‐Controlled, Phase 3 of Tivantinib in Japanese Patients with MET‐high Hepatocellular Carcinoma

(2020) Masatoshi Kudo et al.   CANCER SCIENCE

Green and complementary regioselective synthesis of 3-(1 –substituted pyrazol-3(or 5)-yl)indoles from β-ethyltho-β-indolyl-α,β-unsaturated ketones in water

(2020) Xiao-Bo Zhao et al.   SYNTHETIC COMMUNICATIONS

Research progress in biological activities of succinimide derivatives

(2020) Zefeng Zhao et al.   BIOORGANIC CHEMISTRY

Green and Efficient Synthesis of 3-Pyrazolyl Indoles in Water

(2019) Yanhui Zhao et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Synthesis and biological evaluation of new multi-target 3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives with potential antidepressant effect

(2019) Martyna Z. Wróbel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluoroquinolone-isatin hybrids and their biological activities

(2018) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

(2017) Stefano Crosignani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemoselective Double Annulation of Two Different Isocyanides: Rapid Access to Trifluoromethylated Indole-Fused Heterocycles

(2017) Yuelei Gao et al.   ORGANIC LETTERS

An Approach to 3-(Indol-2-yl)succinimide Derivatives by Manganese-Catalyzed C–H Activation

(2017) Shuang-Liang Liu et al.   ORGANIC LETTERS

Enantiodivergent Brucine Diol-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with α,β-Unsaturated Ketones

(2016) Jian-Yuan Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Site-Selective Addition of Maleimide to Indole at the C-2 Position: Ru(II)-Catalyzed C–H Activation

(2015) Veeranjaneyulu Lanke et al.   ORGANIC LETTERS

Ru (II)-Catalyzed C–H Activation: Ketone-Directed Novel 1,4-Addition of Ortho C–H Bond to Maleimides

(2015) Kiran R. Bettadapur et al.   ORGANIC LETTERS

Regioselective Hetero-Michael Addition of Oxygen, Sulfur, and Nitrogen­ Nucleophiles to Maleimides Catalyzed by BF3·OEt2

(2015) Sheng-Yin Zhao et al.   SYNTHESIS-STUTTGART

Aromatic-Amide-Derived Nonbiaryl Atropisomer as Highly Efficient Ligand for Asymmetric Silver-Catalyzed [3 + 2] Cycloaddition

(2015) Xing-Feng Bai et al.   ACS Catalysis

Synthesis and biological evaluation of novel pyrrolidine-2,5-dione derivatives as potential antidepressant agents. Part 1

(2013) Martyna Z. Wróbel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis

(2013) Tetiana Matviiuk et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

(4+2) Dimerization of imides of arylmaleic acids in the presence of the 3,5-dimethyl-1H-pyrazole and 2,6-lutidine

(2010) Alexander V. Stepakov et al.   TETRAHEDRON