Article
Chemistry, Analytical
Zhanhong Li, Yuwei Wang, Zheyuan Fan, Yufan Sun, Yue Sun, Yiduo Yang, Yifan Zhang, Junjie Ma, Zifeng Wang, Zhigang Zhu
Summary: In this study, a dual-function wearable electrochemical sensor for uric acid and glucose detection in sweat was proposed. The sensor exhibited high sensitivity and selectivity, and showed feasibility for real sample sensing in sweat.
Article
Chemistry, Analytical
Yaoyu Tan, Mengyao Qi, Huan Jiang, Baihui Wang, Xia Zhang
Summary: The VO-MnCo2O4/Ag nanozyme, prepared by hydrothermal, calcination, and self-reduction methods, showed high uricase-like activity and peroxidase-like activity due to its composition and structure. The catalytic reaction of VO-MnCo2O4/Ag nanozyme significantly enhanced the SERS signal of the detected molecule. A label-free, sensitive, and reliable SERS uric acid detection system was developed based on the enzyme-like activities of VO-MnCo2O4/Ag.
ANALYTICA CHIMICA ACTA
(2023)
Article
Multidisciplinary Sciences
Umesha Mogera, Heng Guo, Myeong Namkoong, Md Saifur Rahman, Tan Nguyen, Limei Tian
Summary: Wearable sweat sensors have the potential to provide clinically meaningful information associated with the health and disease states of individuals. Researchers have introduced a wearable plasmonic paper-based microfluidic system that utilizes label-free surface-enhanced Raman spectroscopy (SERS) to detect and quantify metabolites in sweat. This system allows for continuous and simultaneous analysis of sweat loss, sweat rate, and specific biomarkers, providing valuable information for monitoring individual health.
Article
Nanoscience & Nanotechnology
Yuemeng Cheng, Shaoqing Feng, Qihong Ning, Tangan Li, Hao Xu, Qingwen Sun, Daxiang Cui, Kan Wang
Summary: In this research, a small, convenient, and noninvasive paper-based microfluidic sweat sensor was designed and implemented to detect multiple key biomarkers in human sweat simultaneously. The chip's origami structure includes colorimetric and electrochemical sensing regions. Specific chromogenic reagents are used to selectively identify glucose, lactate, uric acid, magnesium ions, and the pH value in different colorimetric sensing regions. The cortisol in sweat is detected by molecular imprinting in the electrochemical sensing regions. The proposed sweat sensor, composed of hydrophilically and hydrophobically treated filter paper, and 3D microfluidic channels formed by folding paper, has been verified to reliably and noninvasively identify a variety of sweat biomarkers through on-body experiments.
MICROSYSTEMS & NANOENGINEERING
(2023)
Review
Nanoscience & Nanotechnology
Fupeng Gao, Chunxiu Liu, Lichao Zhang, Tiezhu Liu, Zheng Wang, Zixuan Song, Haoyuan Cai, Zhen Fang, Jiamin Chen, Junbo Wang, Mengdi Han, Jun Wang, Kai Lin, Ruoyong Wang, Mingxiao Li, Qian Mei, Xibo Ma, Shuli Liang, Guangyang Gou, Ning Xue
Summary: Flexible wearable sweat sensors have attracted significant attention for their potential applications in personalized health monitoring, allowing continuous, real-time, noninvasive detection of sweat analytes and providing insights into human physiology at the molecular level. Electrochemical sensors are the best choice for these sensors due to their high performance, low cost, miniaturization, and wide applicability. Recent advancements in soft microfluidics, multiplexed biosensing, energy harvesting devices, and materials have improved the compatibility and performance of wearable electrochemical sweat-sensing platforms.
MICROSYSTEMS & NANOENGINEERING
(2023)
Article
Chemistry, Analytical
Zhenying Xu, Jingyao Song, Bingrui Liu, Shaoping Lv, Fengxian Gao, Xiliang Luo, Peipei Wang
Summary: The wearable microfluidic-based electrochemical sensor incorporating conducting polymer PEDOT:PSS hydrogel provides an accurate and sensitive detection of uric acid (UA) in human sweat. It shows ultrahigh sensitivity and low limit of detection, allowing real-time monitoring of UA levels in human sweat samples with high correlation to ELISA results.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Xuedian Wei, Miaomiao Zhu, Jialu Li, Liu Liu, Jianyong Yu, Zhaoling Li, Bin Ding
Summary: A research team has developed a flexible sweat biosensor based on a fiber structured sensing interface for uric acid detection. This sensor offers high sensitivity and precise detection of uric acid concentration.
Article
Chemistry, Analytical
Fotini Vasiliou, Alexios K. Plessas, Anastasios Economou, Nicolaos Thomaidis, Giannis S. Papaefstathiou, Christos Kokkinos
Summary: In this work, a new type of graphite paste electrode modified with a water-stable Cu(II)-complex was used for the voltammetric determination of glucose and uric acid in sweat. The electrode showed favorable electrochemical performance and low limits of detection for both biomarkers, without interference from common electroactive metabolites.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Biomedical
F. Vivaldi, A. Dallinger, N. Poma, A. Bonini, D. Biagini, P. Salvo, F. Borghi, A. Tavanti, F. Greco, F. Di Francesco
Summary: The scientific community is increasingly interested in using laser scribing to directly fabricate conductive graphene-based tracks for noninvasive analysis of biofluids. This study presents a wearable sensing platform based on laser-induced graphene electrodes, which allows for the sampling of sweat. The device features a fully laser-manufactured design and has been successfully tested in real-life scenarios.
APL BIOENGINEERING
(2022)
Article
Biochemical Research Methods
Shirun Peng, Dechan Lu, Bohan Zhang, Ruiyun You, Jingbo Chen, Huiyao Xu, Yudong Lu
Summary: Liquid biopsies have significant potential for early detection of colon cancer. Researchers have developed a label-free and non-invasive detection method using surface-enhanced Raman spectroscopy (SERS) with silver nanoparticles as the substrates. By combining this method with machine learning algorithms, accurate diagnosis models for colon cancer can be established.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Hyun Soo Kim, Hyun Jung Kim, Jaehun Lee, Taeha Lee, Jongsu Yun, Gyudo Lee, Yoochan Hong
Summary: The paper presents a method for liquid biopsy analysis using SERS technology, including the fabrication of a SERS substrate with silver nanosnowflakes for simultaneous detection of creatinine and cortisol in human sweat.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Jihong Min, Jiaobing Tu, Changhao Xu, Heather Lukas, Soyoung Shin, Yiran Yang, Samuel A. Solomon, Daniel Mukasa, Wei Gao
Summary: Wearable sensors have the potential to revolutionize personalized healthcare by enabling continuous and noninvasive monitoring of analytes in sweat. However, there are challenges in improving sweat extraction and sensing capabilities, developing comfortable and reliable wearable devices, and understanding the clinical value of sweat analytes for biomarker discovery.
Article
Engineering, Environmental
Paulo A. Raymundo-Pereira, Nathalia O. Gomes, Sergio A. S. Machado, Osvaldo N. Oliveira Jr
Summary: This paper reports on wearable glove-embedded sensors for non-invasive and selective determination of therapeutic drugs and biomarkers in sweat samples. The sensors showed high sensitivity and selectivity, as well as robustness against multiple flexion cycles.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Spectroscopy
Jinqi Fan, Xinyu Fang, Yongling Zhang, Lanxin Xu, Ziqi Zhao, Chenjie Gu, Xingfei Zhou, Dong Chen, Tao Jiang
Summary: Due to poor signal uniformity and external interference, ultrasensitive surface-enhanced Raman spectroscopy (SERS) still faces difficulties in reliable and quantitative detection of trace molecules. In this study, a facile Ag/Si/sodium carboxy methyl cellulose (NaCMC) film with internal standard (IS) was developed, which showed high sensitivity and uniformity as a flexible SERS substrate. Experimental results demonstrated the feasibility of the proposed substrate, and successful monitoring of trace pesticide residues was achieved.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Nanoscience & Nanotechnology
Jiaming Chen, Yuanyuan Yang, Bingyong Lin, Xueju Wei, Zhenyu Lin, Guolin Hong
Summary: A plasmonic gel bead was developed for rapid and effective detection of aqueous samples with high sensitivity and reproducibility. The gel bead contains gold nanobipyramids and an aqueous sample, forming a three-dimensional SERS-active gel network for trapping analytes and offering a uniform hotspot region, resulting in reproducible and uniform signal generation. The method shows excellent reproducibility and detection limit, and has potential for monitoring disease-related biomarkers and point-of-care testing.
ACS APPLIED NANO MATERIALS
(2021)
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)