Integrating Artificial Intelligence and Machine Learning Into Cancer Clinical Trials

Performance of clinician prediction of survival in oncology outpatients with advanced cancer

(2022) Yu Jung Kim et al.   PLoS One

Machine learning approaches to predicting no-shows in pediatric medical appointment

(2022) Dianbo Liu et al.   npj Digital Medicine

Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials

(2022) Andre Esteva et al.   npj Digital Medicine

Screening for Extranodal Extension with Deep Learning: Evaluation in ECOG-ACRIN E3311, a Randomized De-Escalation Trial for HPV-Associated Oropharyngeal Carcinoma

(2022) B.H. Kann et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Use of Machine Learning and Lay Care Coaches to Increase Advance Care Planning Conversations for Patients With Metastatic Cancer

(2022) Michael F. Gensheimer et al.   JCO Oncology Practice

Missing Data in Clinical Studies

(2021) Amit K. Chowdhry et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002)

(2021) Sue S. Yom et al.   JOURNAL OF CLINICAL ONCOLOGY

Handling Poor Accrual in Pediatric Trials: A Simulation Study Using a Bayesian Approach

(2021) Danila Azzolina et al.   International Journal of Environmental Research and Public Health

Application of machine learning in predicting hospital readmissions: a scoping review of the literature

(2021) Yinan Huang et al.   BMC Medical Research Methodology

Evaluating eligibility criteria of oncology trials using real-world data and AI

(2021) Ruishan Liu et al.   NATURE

Recurrence and Quality-of-Life Following Involved Node Radiotherapy for Head and Neck Squamous Cell Carcinoma: Initial Results From the Phase II INRT-Air Trial

(2021) D.J. Sher et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Phase II Randomized Trial of Transoral Surgery and Low-Dose Intensity Modulated Radiation Therapy in Resectable p16+ Locally Advanced Oropharynx Cancer: An ECOG-ACRIN Cancer Research Group Trial (E3311)

(2021) Robert L. Ferris et al.   JOURNAL OF CLINICAL ONCOLOGY

Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy

(2020) Lucas M. Fleuren et al.   INTENSIVE CARE MEDICINE

Alpha Test of Intelligent Machine Learning in Staging Head and Neck Cancer

(2020) Brian O’Sullivan et al.   JOURNAL OF CLINICAL ONCOLOGY

Machine Learning Approach to Identify Stroke Within 4.5 Hours

(2020) Hyunna Lee et al.   STROKE

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer

(2020) Steven H. Lin et al.   JOURNAL OF CLINICAL ONCOLOGY

Reply to A.B. Simon et al

(2020) Benjamin H. Kann et al.   JOURNAL OF CLINICAL ONCOLOGY

Challenge of Directly Comparing Imaging-Based Diagnoses Made by Machine Learning Algorithms With Those Made by Human Clinicians

(2020) Aaron B. Simon et al.   JOURNAL OF CLINICAL ONCOLOGY

Genomics models in radiotherapy: From mechanistic to machine learning

(2020) John Kang et al.   MEDICAL PHYSICS

System for High-Intensity Evaluation During Radiation Therapy (SHIELD-RT): A Prospective Randomized Study of Machine Learning–Directed Clinical Evaluations During Radiation and Chemoradiation

(2020) Julian C. Hong et al.   JOURNAL OF CLINICAL ONCOLOGY

Effect of Integrating Machine Learning Mortality Estimates With Behavioral Nudges to Clinicians on Serious Illness Conversations Among Patients With Cancer

(2020) Christopher R. Manz et al.   JAMA Oncology

Validation of a Machine Learning Algorithm to Predict 180-Day Mortality for Outpatients With Cancer

(2020) Christopher R. Manz et al.   JAMA Oncology

Automated model versus treating physician for predicting survival time of patients with metastatic cancer

(2020) Michael F Gensheimer et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Prospective Phase 2 Study of Radiation Therapy Dose and Volume De-escalation for Elective Neck Treatment of Oropharyngeal and Laryngeal Cancer

(2020) David J. Sher et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

A clinically applicable approach to continuous prediction of future acute kidney injury

(2019) Nenad Tomašev et al.   NATURE

Head and Neck Cancer Adaptive Radiation Therapy (ART): Conceptual Considerations for the Informed Clinician

(2019) Jolien Heukelom et al.   SEMINARS IN RADIATION ONCOLOGY

Performance of a Deep-Learning Algorithm vs Manual Grading for Detecting Diabetic Retinopathy in India

(2019) Varun Gulshan et al.   JAMA Ophthalmology

Phase II Trial of De-Intensified Chemoradiotherapy for Human Papillomavirus–Associated Oropharyngeal Squamous Cell Carcinoma

(2019) Bhishamjit S. Chera et al.   JOURNAL OF CLINICAL ONCOLOGY

Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma

(2019) Benjamin H. Kann et al.   JOURNAL OF CLINICAL ONCOLOGY

Radiologic-Pathologic Correlation of Extranodal Extension in Patients With Squamous Cell Carcinoma of the Oral Cavity: Implications for Future Editions of the TNM Classification

(2018) Abdullah Almulla et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non–Small-Cell Lung Cancer

(2018) Zhongxing Liao et al.   JOURNAL OF CLINICAL ONCOLOGY

OUP accepted manuscript

(2018)   JNCI-Journal of the National Cancer Institute

Pretreatment Identification of Head and Neck Cancer Nodal Metastasis and Extranodal Extension Using Deep Learning Neural Networks

(2018) Benjamin H. Kann et al.   Scientific Reports

Dermatologist-level classification of skin cancer with deep neural networks

(2017) Andre Esteva et al.   NATURE

Estimating Survival in Patients With Lung Cancer and Brain Metastases

(2017) Paul W. Sperduto et al.   JAMA Oncology

Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era

(2017) Erica Hlavin Bell et al.   JAMA Oncology

Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs

(2016) Varun Gulshan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Machine Learning Approaches for Predicting Radiation Therapy Outcomes: A Clinician's Perspective

(2015) John Kang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Deep learning

(2015) Yann LeCun et al.   NATURE

Diagnostic Accuracy of Digital Screening Mammography With and Without Computer-Aided Detection

(2015) Constance D. Lehman et al.   JAMA Internal Medicine

Can oncologists predict survival for patients with progressive disease after standard chemotherapies?

(2014) T.K. Taniyama et al.   Current Oncology

The Parable of Google Flu: Traps in Big Data Analysis

(2014) D. Lazer et al.   SCIENCE

Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases

(2011) Paul W. Sperduto et al.   JOURNAL OF CLINICAL ONCOLOGY

Receiver Operating Characteristic Curve in Diagnostic Test Assessment

(2010) Jayawant N. Mandrekar   Journal of Thoracic Oncology

Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer

(2010) Jennifer S. Temel et al.   NEW ENGLAND JOURNAL OF MEDICINE