Up-regulation of the Trace Amine Receptor, TAAR-1, in the Prefrontal Cortex of Individuals Affected by Schizophrenia

TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-383856

(2022) Marcus Saarinen et al.   NEUROPSYCHOPHARMACOLOGY

Ulotaront: a TAAR1/5-HT1A agonist in clinical development for the treatment of schizophrenia

(2022) Mikkel Højlund et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Trace amine-associated receptor 1 (TAAR1) agonism as a new treatment strategy for schizophrenia and related disorders

(2022) Els F. Halff et al.   TRENDS IN NEUROSCIENCES

TAAR1 Expression in Human Macrophages and Brain Tissue: A Potential Novel Facet of MS Neuroinflammation

(2021) David A. Barnes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Safety and effectiveness of ulotaront (SEP-363856) in schizophrenia: results of a 6-month, open-label extension study

(2021) Christoph U. Correll et al.   npj Schizophrenia

A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia

(2020) Kenneth S. Koblan et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia

(2020) Martina Ulivieri et al.   SCHIZOPHRENIA BULLETIN

Trace Amine-Associated Receptor 1 Agonist Modulates Mismatch Negativity-Like Responses in Mice

(2019) Aleksander A. Aleksandrov et al.   Frontiers in Pharmacology

SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION

(2019) Nina Dedic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Action of TAAR1 Agonist RO5263397 on Executive Functions in Rats

(2019) Artem Dorotenko et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Molecular Variants in Human Trace Amine-Associated Receptors and Their Implications in Mental and Metabolic Disorders

(2019) Grazia Rutigliano et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Effect of trace amine-associated receptor 1 agonist RO5263397 on sensory gating in mice

(2019) Aleksander A. Aleksandrov et al.   NEUROREPORT

Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors

(2019) Tiziana Imbriglio et al.   FASEB JOURNAL

Trace Amines and Their Receptors

(2018) Raul R. Gainetdinov et al.   PHARMACOLOGICAL REVIEWS

Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine

(2018) Xiaoqun Zhang et al.   Frontiers in Pharmacology

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

Possible role of rare variants in Trace amine associated receptor 1 in schizophrenia

(2017) Jibin John et al.   SCHIZOPHRENIA RESEARCH

Molecular Evolution and Functional Divergence of Trace Amine–Associated Receptors

(2016) Seong-il Eyun et al.   PLoS One

Alterations in Cortical Network Oscillations and Parvalbumin Neurons in Schizophrenia

(2015) Guillermo Gonzalez-Burgos et al.   BIOLOGICAL PSYCHIATRY

Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers

(2015) Anja Harmeier et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

TAAR1 Modulates Cortical Glutamate NMDA Receptor Function

(2015) Stefano Espinoza et al.   NEUROPSYCHOPHARMACOLOGY

A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight

(2012) F G Revel et al.   MOLECULAR PSYCHIATRY

Brain-Specific Overexpression of Trace Amine-Associated Receptor 1 Alters Monoaminergic Neurotransmission and Decreases Sensitivity to Amphetamine

(2012) Florent G Revel et al.   NEUROPSYCHOPHARMACOLOGY

Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA)

(2011) B. Di Cara et al.   JOURNAL OF NEUROSCIENCE

From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment

(2011) Bita Moghaddam et al.   NEUROPSYCHOPHARMACOLOGY

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

(2011) F. G. Revel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt/GSK3 Signaling in the Action of Psychotropic Drugs

(2008) Jean-Martin Beaulieu et al.   Annual Review of Pharmacology and Toxicology

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Trace amine-associated receptors and their ligands

(2006) R Zucchi et al.   BRITISH JOURNAL OF PHARMACOLOGY