Mesenchymal stem cell-derived HGF attenuates radiation-induced senescence in salivary glands via compensatory proliferation

Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction (MARSH): Study protocol for a phase 1 dose-escalation trial of patients with xerostomia after radiation therapy for head and neck cancer

(2022) Grace C. Blitzer et al.   CYTOTHERAPY

Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial

(2022) Charlotte Duch Lynggaard et al.   CLINICAL CANCER RESEARCH

The evolving definition of salivary gland stem cells

(2021) Cecilia Rocchi et al.   npj Regenerative Medicine

Biological functions of therapy-induced senescence in cancer

(2021) Eleni Fitsiou et al.   SEMINARS IN CANCER BIOLOGY

Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche

(2020) Xiaohong Peng et al.   Cell Death & Disease

Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development

(2020) Belinda R. Hauser et al.   iScience

Regulation of Survival Networks in Senescent Cells: From Mechanisms to Interventions

(2019) Abel Soto-Gamez et al.   JOURNAL OF MOLECULAR BIOLOGY

Safety and Efficacy of Mesenchymal Stem Cells for Radiation-Induced Xerostomia: A Randomized, Placebo-Controlled Phase 1/2 Trial (MESRIX)

(2018) Christian Grønhøj et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

First-in-man mesenchymal stem cells for radiation-induced xerostomia (MESRIX): study protocol for a randomized controlled trial

(2017) Christian Grønhøj et al.   Trials

Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment

(2017) Benjamin Owusu et al.   Cancers

Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation

(2016) Y. Marmary et al.   CANCER RESEARCH

Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

(2016) Martti Maimets et al.   Stem Cell Reports

Current ideas to reduce or salvage radiation damage to salivary glands

(2014) A Vissink et al.   ORAL DISEASES

Purification and Ex Vivo Expansion of Fully Functional Salivary Gland Stem Cells

(2014) Lalitha S.Y. Nanduri et al.   Stem Cell Reports

Mesenchymal Stem Cells: Mechanisms of Inflammation

(2011) Nora G. Singer et al.   Annual Review of Pathology-Mechanisms of Disease

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS