Combination of local radiotherapy and anti-glucocorticoid-induced tumor necrosis factor receptor (GITR) therapy augments PD-L1 blockade-mediated anti-tumor effects in murine breast cancer model
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Title
Combination of local radiotherapy and anti-glucocorticoid-induced tumor necrosis factor receptor (GITR) therapy augments PD-L1 blockade-mediated anti-tumor effects in murine breast cancer model
Authors
Keywords
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Journal
RADIOTHERAPY AND ONCOLOGY
Volume -, Issue -, Pages 109981
Publisher
Elsevier BV
Online
2023-11-03
DOI
10.1016/j.radonc.2023.109981
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Note: Only part of the references are listed.- Combination of OX40 Co-Stimulation, Radiotherapy, and PD-1 Inhibition in a Syngeneic Murine Triple-Negative Breast Cancer Model
- (2022) Min Guk Han et al. Cancers
- Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/− trastuzumab in patients with breast cancer brain metastases
- (2022) David B. Page et al. npj Breast Cancer
- Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor Microenvironment
- (2021) Xianwen Ren et al. Annual Review of Immunology
- PI3Kαδ Inhibitor Combined With Radiation Enhances the Antitumor Immune Effect of Anti-PD1 in a Syngeneic Murine Triple-Negative Breast Cancer Model
- (2021) Won Ick Chang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- The Dynamic alternation of Local and Systemic Tumor Immune Microenvironment during Concurrent Chemoradiotherapy of Cervical Cancer: A Prospective Clinical Trial
- (2021) Rui Li et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment
- (2021) Kristen E. Pauken et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer
- (2021) Ayse Bassez et al. NATURE MEDICINE
- Triple-modality therapy maximizes antitumor immune responses in a mouse model of mesothelioma
- (2021) Junichi Murakami et al. Science Translational Medicine
- Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas
- (2021) Zohreh Amoozgar et al. Nature Communications
- Mechanisms of Immune Modulation by Radiation
- (2021) Catherine S. Spina et al. SEMINARS IN RADIATION ONCOLOGY
- PI3Kγδ inhibitor plus radiation enhances the antitumour immune effect of PD-1 blockade in syngenic murine breast cancer and humanised patient-derived xenograft model
- (2021) Min Guk Han et al. EUROPEAN JOURNAL OF CANCER
- Regulatory T Cells Shape the Differential Impact of Radiation Dose-Fractionation Schedules on Host Innate and Adaptive Antitumor Immune Defenses
- (2021) Joseph Sia et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- A Phase II Study of Pembrolizumab in Combination With Palliative Radiotherapy for Hormone Receptor-positive Metastatic Breast Cancer
- (2020) Romualdo Barroso-Sousa et al. Clinical Breast Cancer
- The Promise of Combining Radiation Therapy With Immunotherapy
- (2020) Justin C. Jagodinsky et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Type I Interferon Response in Radiation-Induced Anti-Tumor Immunity
- (2020) Faya Zhang et al. SEMINARS IN RADIATION ONCOLOGY
- Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
- (2020) David Y. Oh et al. CELL
- Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors
- (2020) Ani S. Balmanoukian et al. CLINICAL CANCER RESEARCH
- PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
- (2020) Catherine L. Tan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies
- (2020) Shogo Kumagai et al. NATURE IMMUNOLOGY
- Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
- (2019) Leonie Voorwerk et al. NATURE MEDICINE
- PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
- (2019) Takahiro Kamada et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonal replacement of tumor-specific T cells following PD-1 blockade
- (2019) Kathryn E. Yost et al. NATURE MEDICINE
- Recruit or Reboot? How Does Anti-PD-1 Therapy Change Tumor-Infiltrating Lymphocytes?
- (2019) Margaret K. Callahan et al. CANCER CELL
- A phase 2 clinical trial assessing the efficacy and safety of pembrolizumab and radiotherapy in patients with metastatic triple‐negative breast cancer
- (2019) Alice Y. Ho et al. CANCER
- Safety, Tolerability, and Potential Clinical Activity of a Glucocorticoid-Induced TNF Receptor–Related Protein Agonist Alone or in Combination With Nivolumab for Patients With Advanced Solid Tumors
- (2019) Kimberley M. Heinhuis et al. JAMA Oncology
- Long-term Clinical Outcomes and Biomarker Analyses of Atezolizumab Therapy for Patients With Metastatic Triple-Negative Breast Cancer
- (2018) Leisha A. Emens et al. JAMA Oncology
- Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study
- (2018) S Adams et al. ANNALS OF ONCOLOGY
- Radiotherapy induces responses of lung cancer to CTLA-4 blockade
- (2018) Silvia C. Formenti et al. NATURE MEDICINE
- Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
- (2018) Peter Schmid et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
- (2017) Claire Vanpouille-Box et al. Nature Communications
- Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment
- (2017) Yuki Muroyama et al. Cancer Immunology Research
- Dual Roles for Regulatory T-cell Depletion and Costimulatory Signaling in Agonistic GITR Targeting for Tumor Immunotherapy
- (2016) Ashley E. Mahne et al. CANCER RESEARCH
- Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study
- (2016) Rita Nanda et al. JOURNAL OF CLINICAL ONCOLOGY
- Immune modulation by hypofractionated stereotactic radiation therapy: Therapeutic implications
- (2016) Ilinca Popp et al. RADIOTHERAPY AND ONCOLOGY
- Mechanism of Action of Conventional and Targeted Anticancer Therapies: Reinstating Immunosurveillance
- (2013) Laurence Zitvogel et al. IMMUNITY
- Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies
- (2013) Yannick Bulliard et al. JOURNAL OF EXPERIMENTAL MEDICINE
- GITR Pathway Activation Abrogates Tumor Immune Suppression through Loss of Regulatory T-cell Lineage Stability
- (2013) D. A. Schaer et al. Cancer Immunology Research
- Modulation of GITR for cancer immunotherapy
- (2012) David A Schaer et al. CURRENT OPINION IN IMMUNOLOGY
- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
- (2012) Christina Curtis et al. NATURE
- CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity
- (2011) Rodolfo Bianchini et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy
- (2010) David Coe et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Agonist Anti-GITR Monoclonal Antibody Induces Melanoma Tumor Immunity in Mice by Altering Regulatory T Cell Stability and Intra-Tumor Accumulation
- (2010) Adam D. Cohen et al. PLoS One
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