IRE1α/XBP-1 promotes β-catenin signaling activation of airway epithelium in lipopolysaccharide-induced acute lung injury

A New Link in the Chain: Unspliced XBP1 in Wnt Signaling and Vascular Calcification

(2022) Peiran Yang et al.   CIRCULATION RESEARCH

Acute Intoxication With Alcohol Reduces Trauma-Induced Proinflammatory Response and Barrier Breakdown in the Lung via the Wnt/β-Catenin Signaling Pathway

(2022) Laurens Noack et al.   Frontiers in Immunology

Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway

(2021) Haibin Cui et al.   Journal of Anesthesia

A mechanism for matrikine regulation in acute inflammatory lung injury

(2021) Sarah W. Robison et al.   JCI Insight

Impaired airway epithelial barrier integrity was mediated by PI3Kδ in a mouse model of lipopolysaccharide-induced acute lung injury

(2021) Lihong Yao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of TREM-1 induces endoplasmic reticulum stress through IRE-1α/XBP-1s pathway in murine macrophages

(2021) Liang Dong et al.   MOLECULAR IMMUNOLOGY

Diversity of Macrophages in Lung Homeostasis and Diseases

(2021) Fei Hou et al.   Frontiers in Immunology

Inhibition of the endoplasmic reticulum (ER) stress-associated IRE-1/XBP-1 pathway alleviates acute lung injury via modulation of macrophage activation

(2020) Yanfeng Zhao et al.   Journal of Thoracic Disease

Mechanism of inositol-requiring enzyme 1-alpha inhibition in endoplasmic reticulum stress and apoptosis in ovarian cancer cells

(2020) Shekufe Rezghi Barez et al.   Journal of Cell Communication and Signaling

TNF‑α promotes the malignant transformation of intestinal stem cells through the NF‑κB and Wnt/β‑catenin signaling pathways

(2020) Xiaopeng Zhao et al.   ONCOLOGY REPORTS

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

Protective effects of febuxostat against paraquat-induced lung toxicity in rats: Impact on RAGE/PI3K/Akt pathway and downstream inflammatory cascades

(2019) Maha A.E. Ahmed et al.   LIFE SCIENCES

CRBN knockdown mitigates lipopolysaccharide-induced acute lung injury by suppression of oxidative stress and endoplasmic reticulum (ER) stress associated NF-κB signaling

(2019) Huobao Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Neutrophils induce smooth muscle hyperplasia via neutrophil elastase-induced FGF-2 in a mouse model of asthma with mixed inflammation

(2018) Hirohisa Ogawa et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells

(2017) X-X Li et al.   ONCOGENE

The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model

(2016) Lihong Yao et al.   BRITISH JOURNAL OF PHARMACOLOGY

NOD1 and NOD2 signalling links ER stress with inflammation

(2016) A. Marijke Keestra-Gounder et al.   NATURE

Targeting the IRE1α–XBP1 branch of the unfolded protein response in human diseases

(2015) Dadi Jiang et al.   SEMINARS IN CANCER BIOLOGY

Phosphatidylinositol 3-Kinase Mediates β-Catenin Dysfunction of Airway Epithelium in a Toluene Diisocyanate-Induced Murine Asthma Model

(2015) Lihong Yao et al.   TOXICOLOGICAL SCIENCES

Human Melanoma Cells under Endoplasmic Reticulum Stress Acquire Resistance to Microtubule-Targeting Drugs through XBP-1-Mediated Activation of Akt

(2015) Chen Chen Jiang et al.   NEOPLASIA

Ethyl pyruvate decreases airway neutrophil infiltration partly through a high mobility group box 1-dependent mechanism in a chemical-induced murine asthma model

(2014) Haixiong Tang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

β-catenin regulates NF-κB activity and inflammatory cytokine expression in bronchial epithelial cells treated with lipopolysaccharide

(2014) JAEWOONG JANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Wnt3a mitigates acute lung injury by reducing P2X7 receptor-mediated alveolar epithelial type I cell death

(2014) Y Guo et al.   Cell Death & Disease

Vascular Endothelial Cell Growth–Activated XBP1 Splicing in Endothelial Cells Is Crucial for Angiogenesis

(2013) Lingfang Zeng et al.   CIRCULATION

Inhibition of Wnt/β-Catenin Signaling Promotes Engraftment of Mesenchymal Stem Cells to Repair Lung Injury

(2013) Zhaorui Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

(2012) B. C. S. Cross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation

(2011) Te I. Weng et al.   INTENSIVE CARE MEDICINE

Neutrophil transmigration triggers repair of the lung epithelium via  -catenin signaling

(2011) R. L. Zemans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production

(2010) M. E. Roberts et al.   EUROPEAN RESPIRATORY JOURNAL

CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury

(2009) Franco R. D’Alessio et al.   JOURNAL OF CLINICAL INVESTIGATION