Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities

Synthesis, in vitro antibacterial activities of a series of 3- N -substituted canthin-6-ones

(2016) Jiang-Kun Dai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursors

(2015) Hsin Wei Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Constituents of the stem barks of Ailanthus altissima and their potential to inhibit LPS-induced nitric oxide production

(2015) Hye Mi Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Canthinone alkaloids are novel protein tyrosine phosphatase 1B inhibitors

(2015) Tatsunori Sasaki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Experimental and theoretical study of possible correlation between the electrochemistry of canthin-6-one and the anti-proliferative activity against human cancer stem cells

(2015) G. Cebrián-Torrejón et al.   JOURNAL OF MOLECULAR STRUCTURE

9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α

(2015) Kensuke Ohishi et al.   JOURNAL OF NATURAL PRODUCTS

Harvesting canthinones: identification of the optimal seasonal point of harvest ofZanthoxylum chiloperoneleaves as a source of 5-methoxycanthin-6-one

(2015) Gerardo Cebrián-Torrejón et al.   NATURAL PRODUCT RESEARCH

Canthin-6-one Displays Antiproliferative Activity and Causes Accumulation of Cancer Cells in the G2/M Phase

(2014) Camille Dejos et al.   JOURNAL OF NATURAL PRODUCTS

NF-κB Inhibitors from Eurycoma longifolia

(2014) Thi Van Anh Tran et al.   JOURNAL OF NATURAL PRODUCTS

Isolation, structural elucidation and cytotoxicity evaluation of a new pentahydroxy-pimarane diterpenoid along with other chemical constituents fromAerva lanata

(2014) Yogesh P. Bharitkar et al.   NATURAL PRODUCT RESEARCH

dsDNA, ssDNA, G-quadruplex DNA, and nucleosomal DNA electrochemical screening using canthin-6-one alkaloid-modified electrodes

(2013) Antonio Doménech-Carbó et al.   ELECTROCHIMICA ACTA

Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties onC. elegans

(2013) Gerardo Cebrián-Torrejón et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The MFS-type efflux pump Flr1 induced by Yap1 promotes canthin-6-one resistance in yeast

(2013) Camille Dejos et al.   FEBS LETTERS

Progress in the Synthesis of Canthine Alkaloids and Ring-Truncated Congeners

(2013) H. D. Hollis Showalter   JOURNAL OF NATURAL PRODUCTS

Compounds from Simarouba berteroana which inhibit proliferation of NF1-defective cancer cells

(2013) Krishna P. Devkota et al.   Phytochemistry Letters

Hyrtimomines D and E, bisindole alkaloids from a marine sponge Hyrtios sp.

(2013) Naonobu Tanaka et al.   TETRAHEDRON LETTERS

Amarastelline A: A Fluorescent Alkaloid from Quassia amara and Its Properties in Living Cells

(2012) Kaori Taniguchi et al.   ChemPlusChem

Modulation of humoral immune responses and inhibition of proinflammatory cytokines and nitric oxide production by 10-methoxycanthin-6-one

(2011) K.S. Siveen et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Three-Step Synthesis of Ethyl Canthinone-3-carboxylates from Ethyl 4-Bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-Catalyzed Suzuki–Miyaura Coupling and a Cu-Catalyzed Amidation Reaction

(2011) Heraklidia A. Ioannidou et al.   JOURNAL OF ORGANIC CHEMISTRY

9‐Hydroxycanthin‐6‐One Induces Penile Erection and Delays Ejaculation

(2011) Wen‐Fei Chiou et al.   Journal of Sexual Medicine

Synthesis and Cytotoxic Activity of New β-Carboline Derivatives

(2011) A. Peduto et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Synthesis and evaluation of β-carboline derivatives as inhibitors of human immunodeficiency virus

(2010) Keyur G. Brahmbhatt et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Zanthoxylum chiloperone leaves extract: First sustainable Chagas disease treatment

(2010) Maria Elena Ferreira et al.   JOURNAL OF ETHNOPHARMACOLOGY

Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki−Miyaura Coupling and Cu-Catalyzed Amidation Reaction

(2010) Andreas Gollner et al.   ORGANIC LETTERS

Baylis–Hillman Reaction of 1-Formyl-β-carboline: One-Step Synthesis of the Canthin-6-one Framework by an Unprecedented Cascade Cyclization Reaction

(2009) Virender Singh et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Tobacco Mosaic Virus (TMV) Inhibitors fromPicrasma quassioidesBenn

(2009) Jia Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A convenient approach to the canthin-4-one ring system: Total synthesis of the alkaloids tuboflavine and norisotuboflavine

(2009) Andreas Puzik et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Antifungal canthin-6-one series accumulate in lipid droplets and affect fatty acid metabolism in Saccharomyces cerevisiae

(2007) D. Lagoutte et al.   BIOMEDICINE & PHARMACOTHERAPY