Synthetic Strategies for 5- and 6-Membered Ring Azaheterocycles Facilitated by Iminyl Radicals

Visible light photoredox-controlled reactions of N-radicals and radical ions

(2016) Jia-Rong Chen et al.   CHEMICAL SOCIETY REVIEWS

Metal-Free Assembly of Polysubstituted Pyridines from Oximes and Acroleins

(2016) Huawen Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Functionalised Oximes: Emergent Precursors for Carbon-, Nitrogen- and Oxygen-Centred Radicals

(2016) John Walton   MOLECULES

The Chemical Space Project

(2015) Jean-Louis Reymond   ACCOUNTS OF CHEMICAL RESEARCH

Pushing the Limits of Neutral Organic Electron Donors: A Tetra(iminophosphorano)-Substituted Bispyridinylidene

(2015) Samuel S. Hanson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Mediated Generation of Nitrogen-Centered Radicals: Metal-Free Hydroimination and Iminohydroxylation Cyclization Reactions

(2015) Jacob Davies et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Promoted Iminyl-Radical Formation from Acyl Oximes: A Unified Approach to Pyridines, Quinolines, and Phenanthridines

(2015) Heng Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photocatalysis with TiO2 Applied to Organic Synthesis

(2015) Norbert Hoffmann   AUSTRALIAN JOURNAL OF CHEMISTRY

Preparative semiconductor photoredox catalysis: An emerging theme in organic synthesis

(2015) David W Manley et al.   Beilstein Journal of Organic Chemistry

Recent advances in the synthesis of nitrogen heterocycles via radical cascade reactions using isonitriles as radical acceptors

(2015) Bo Zhang et al.   CHEMICAL SOCIETY REVIEWS

Drug Likeness and Selective Functionalization of Quinoxalines

(2015) Samuel Ferreira et al.   CURRENT ORGANIC SYNTHESIS

Living on pyrrolic foundations – Advances in natural and artificial bioactive pyrrole derivatives

(2015) Anna Domagala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pseudocyanides of sanguinarine and chelerythrine and their series of structurally simple analogues as new anticancer lead compounds: Cytotoxic activity, structure–activity relationship and apoptosis induction

(2015) Fang-Jun Cao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Recent advances in research of natural and synthetic bioactive quinolines

(2015) Po-Yee Chung et al.   Future Medicinal Chemistry

Radical Reactions of N-Heterocyclic Carbene Boranes with Organic Nitriles: Cyanation of NHC-Boranes and Reductive Decyanation of Malononitriles

(2015) Takuji Kawamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neuroprotective activity and acetylcholinesterase inhibition of five Amaryllidaceae species: A comparative study

(2015) Natalie Cortes et al.   LIFE SCIENCES

Microwave-Promoted Tin-Free Iminyl Radical Cyclization with TEMPO Trapping: A Practical Synthesis of 2-Acylpyrroles

(2015) Yu Cai et al.   ORGANIC LETTERS

Visible-Light-Promoted and One-Pot Synthesis of Phenanthridines and Quinolines from Aldehydes and O-Acyl Hydroxylamine

(2015) Xiao-De An et al.   ORGANIC LETTERS

Synthesis of Highly Functionalized Polycyclic Quinoxaline Derivatives Using Visible-Light Photoredox Catalysis

(2014) Zhi He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Come-back of phenanthridine and phenanthridinium derivatives in the 21st century

(2014) Lidija-Marija Tumir et al.   Beilstein Journal of Organic Chemistry

Design and synthesis of new 7-(N-substituted-methyl)-camptothecin derivatives as potent cytotoxic agents

(2014) Xiao-Bo Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Catalytic Oxidative Cyclization of 2′-Arylbenzaldehyde Oxime Ethers under Photoinduced Electron Transfer Conditions

(2014) Julie L. Hofstra et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery and Development of Organic Super-Electron-Donors

(2014) John A. Murphy   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Fused Quinoline and Quinoxaline Derivatives Enabled by Domino Radical Triple Bond Insertions

(2014) Xiaoyang Sun et al.   Asian Journal of Organic Chemistry

Homogeneous Visible-Light Photoredox Catalysis

(2013) You-Quan Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interplay of ortho-with spiro-cyclisation during iminyl radical closures onto arenes and heteroarenes

(2013) Roy T McBurney et al.   Beilstein Journal of Organic Chemistry

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Dissociation or Cyclization: Options for a Triad of Radicals Released from Oxime Carbamates

(2013) Roy T. McBurney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overturning Established Chemoselectivities: Selective Reduction of Arenes over Malonates and Cyanoacetates by Photoactivated Organic Electron Donors

(2013) Eswararao Doni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative Radical Skeletal Rearrangement Induced by Molecular Oxygen: Synthesis of Quinazolinones

(2013) Yi-Feng Wang et al.   ORGANIC LETTERS

Antitumour activities of sanguinarine and related alkaloids

(2013) Iva Slaninová et al.   PHYTOCHEMISTRY REVIEWS

Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities ofβ-Carboline and Quinoline Alkaloids Derivatives from the Plants of GenusPeganum

(2013) Ting Zhao et al.   Journal of Chemistry

Unconventional Titania Photocatalysis: Direct Deployment of Carboxylic Acids in Alkylations and Annulations

(2012) David W. Manley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2, 3-Disubstituted-Quinazolin-4-(3H)-ones

(2012) D. A. Patil et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Synthesis of 3-Substituted and 2,3-Disubstituted Quinazolinones via Cu-Catalyzed Aryl Amidation

(2012) Lanting Xu et al.   ORGANIC LETTERS

UV promoted phenanthridine syntheses from oxime carbonate derived iminyl radicals

(2011) Roy T. McBurney et al.   CHEMICAL COMMUNICATIONS

Benzo[c]phenanthridine alkaloids exhibit strong anti-proliferative activity in malignant melanoma cells regardless of their p53 status

(2011) Jindřiška Hammerová et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Discovery of (+)-N-(3-Aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a Kinesin Spindle Protein Inhibitor and Potential Anticancer Agent

(2011) Maria-Elena Theoclitou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Quinazolin-4(3H)-ones via Pd(II)-Catalyzed Intramolecular C(sp2)–H Carboxamidation ofN-arylamidines

(2011) Bin Ma et al.   JOURNAL OF ORGANIC CHEMISTRY

Electron Paramagnetic Resonance and Computational Studies of Radicals Derived from Boron-Substituted N-Heterocyclic Carbene Boranes

(2011) John C. Walton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Quinolin-2-one Alkaloid Derivatives and Their Inhibitory Activities against HIV-1 Reverse Transcriptase

(2011) Pi Cheng et al.   MOLECULES

Bioactivity-Guided Navigation of Chemical Space

(2010) Robin S. Bon et al.   ACCOUNTS OF CHEMICAL RESEARCH

Radical Synthesis of Guanidines fromN-Acyl Cyanamides

(2010) Marie-Hélène Larraufie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel Benzimidazole Inhibitors Bind to a Unique Site in the Kinesin Spindle Protein Motor Domain

(2010) Payal R. Sheth et al.   BIOCHEMISTRY

Visible light photoredox catalysis: applications in organic synthesis

(2010) Jagan M. R. Narayanam et al.   CHEMICAL SOCIETY REVIEWS

Modified B-Alkylcatecholboranes as Radical Precursors

(2010) Monique Lüthy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Radical Migration of Substituents of Aryl Groups on Quinazolinones Derived fromN-Acyl Cyanamides

(2010) Marie-Hélène Larraufie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of the Marine Pyrroloiminoquinone Alkaloids, Discorhabdins

(2010) Yasufumi Wada et al.   Marine Drugs

Visible light photocatalysis as a greener approach to photochemical synthesis

(2010) Tehshik P. Yoon et al.   Nature Chemistry

Photochemistry of acyloximes: synthesis of heterocycles and natural products

(2010) Rafael Alonso et al.   TETRAHEDRON

Linking Borane with N-Heterocyclic Carbenes: Effective Hydrogen-Atom Donors for Radical Reactions

(2009) John C. Walton   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, cytotoxic activity, DNA topoisomerase-II inhibition, molecular modeling and structure–activity relationship of 9-anilinothiazolo[5,4-b]quinoline derivatives

(2009) Marco A. Loza-Mejía et al.   BIOORGANIC & MEDICINAL CHEMISTRY

From Azides to Nitrogen-Centered Radicals: Applications of Azide Radical Chemistry to Organic Synthesis

(2009) Matteo Minozzi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Use of Quinoline Alkaloids as Markers of the Floral Origin of Chestnut Honey

(2009) Pilar Truchado et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quinoline alkaloids as intercalative topoisomerase inhibitors

(2009) Kendall G. Byler et al.   JOURNAL OF MOLECULAR MODELING

Microwave-Promoted Syntheses of Quinazolines and Dihydroquinazolines from 2-AminoarylalkanoneO-Phenyl Oximes

(2009) Fernando Portela-Cubillo et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene Boryl Radicals: A New Class of Boron-Centered Radical

(2009) Shau-Hua Ueng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic Applications of Pd(II)-Catalyzed C−H Carboxylation and Mechanistic Insights: Expedient Routes to Anthranilic Acids, Oxazolinones, and Quinazolinones

(2009) Ramesh Giri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular features of the prazosin molecule required for activation of Transport-P

(2008) Joaquim Fernando Mendes da Silva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines

(2008) Fernando Portela-Cubillo et al.   CHEMICAL COMMUNICATIONS

Recent progress in the generation and use of nitrogen-centred radicals

(2008) Samir Z. Zard   CHEMICAL SOCIETY REVIEWS

Advances in the Syntheses of Quinoline and Quinoline-Annulated Ring Systems&#

(2008) Sudharshan Madapa et al.   CURRENT ORGANIC CHEMISTRY

Design, Synthesis and Development of Novel Camptothecin Drugs

(2008) Siong Liew et al.   CURRENT PHARMACEUTICAL DESIGN

Discovery of Novel Small-Molecule Inhibitors of Human Epidermal Growth Factor Receptor-2: Combined Ligand and Target-Based Approach

(2008) Rambabu Gundla et al.   JOURNAL OF MEDICINAL CHEMISTRY

Microwave-Assisted Syntheses ofN-Heterocycles Using Alkenone-, Alkynone- and Aryl-carbonylO-Phenyl Oximes: Formal Synthesis of Neocryptolepine

(2008) Fernando Portela-Cubillo et al.   JOURNAL OF ORGANIC CHEMISTRY

Photocyclization of Iminyl Radicals:  Theoretical Study and Photochemical Aspects

(2008) Rafael Alonso et al.   JOURNAL OF ORGANIC CHEMISTRY

Induction of NAD(P)H:Quinone Reductase by Rutaecarpine Isolated from the Fruits ofEvodia rutaecarpain the Murine Hepatic Hepa-1c1c7 Cell Line

(2008) Hyunjin Ahn et al.   PLANTA MEDICA

Dioxime oxalates; new iminyl radical precursors for syntheses of N-heterocycles

(2008) Fernando Portela-Cubillo et al.   TETRAHEDRON

Unprecedented Aromatic Homolytic Substitutions and Cyclization of AmideIminyl Radicals: Experimental and Theoretical Study

(2007) Aurore Beaume et al.   CHEMISTRY-A EUROPEAN JOURNAL

Syntheses of 4-(indole-3-yl)quinazolines – A new class of epidermal growth factor receptor tyrosine kinase inhibitors

(2007) Anja Lüth et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY