From preschool wheezing to asthma: Immunological determinants

Development of Sensitization to Multiple Allergen Molecules from Preschool to School Age Is Related to Asthma

(2022) Anastasia Filiou et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Proteomics endotyping of infants with severe bronchiolitis and risk of childhood asthma

(2022) Tadao Ooka et al.   ALLERGY

T-high asthma phenotypes across life span

(2022) Nicole Maison et al.   EUROPEAN RESPIRATORY JOURNAL

Alarmins and innate lymphoid cells 2 activation: A common pathogenetic link connecting respiratory syncytial virus bronchiolitis and later wheezing/asthma?

(2022) Giovanni A. Rossi et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Microbiota, Epigenetics and Trained Immunity: Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood

(2021) Susan V Lynch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mitogen‐activated protein kinase signaling in childhood asthma development and environment‐mediated protection

(2021) Johanna Theodorou et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

The JAK1/2 inhibitor baricitinib suppresses eosinophil effector function and restricts allergen-induced airway eosinophilia

(2021) Petra Luschnig et al.   BIOCHEMICAL PHARMACOLOGY

17q12‐21 risk‐variants influence cord blood immune regulation and multitrigger‐wheeze

(2021) Kristina Laubhahn et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze

(2021) Thomas Iosifidis et al.   Journal of Personalized Medicine

Emerging Regulatory Roles of Dual-Specificity Phosphatases in Inflammatory Airway Disease

(2019) Grace Manley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection

(2019) Johanna Krusche et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dendritic cells conditioned by activin A–induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma

(2018) Maria Semitekolou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Machine learning to identify pairwise interactions between specific IgE antibodies and their association with asthma: A cross-sectional analysis within a population-based birth cohort

(2018) Sara Fontanella et al.   PLOS MEDICINE

Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny

(2017) Tobias R. Kollmann et al.   IMMUNITY

Evolution and predictive value of IgE responses toward a comprehensive panel of house dust mite allergens during the first 2 decades of life

(2017) Daniela Posa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts

(2017) Alexander J. Hose et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence

(2017) Frederick J. Rubner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A switch in regulatory T cells through farm exposure during immune maturation in childhood

(2016) P. C. Schröder et al.   ALLERGY

Rhinovirus-specific antibody responses in preschool children with acute wheeze reflect severity of respiratory symptoms

(2016) K. Stenberg-Hammar et al.   ALLERGY

Targeting the JAK-STAT pathway in the treatment of ‘Th2-high’ severe asthma

(2016) Kara Vale   Future Medicinal Chemistry

Allergen-Experienced Group 2 Innate Lymphoid Cells Acquire Memory-like Properties and Enhance Allergic Lung Inflammation

(2016) Itziar Martinez-Gonzalez et al.   IMMUNITY

Farm exposures are associated with lower percentage of circulating myeloid dendritic cell subtype 2 at age 6

(2015) M.-V. Martikainen et al.   ALLERGY

Mechanisms of allergic disease - environmental and genetic determinants for the development of allergy

(2015) D. E. Campbell et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Asthma phenotypes and IgE responses

(2015) Antoine Froidure et al.   EUROPEAN RESPIRATORY JOURNAL

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33

(2015) Christina A. Christianson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of novel immune phenotypes for allergic and nonallergic childhood asthma

(2015) Diana Raedler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses

(2015) Timotheus Y F Halim et al.   NATURE IMMUNOLOGY

Budesonide increases TLR4 and TLR2 expression in Treg lymphocytes of allergic asthmatics

(2015) Elisabetta Pace et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Circulating Dendritic Cells, Farm Exposure and Asthma at Early Age

(2015) H. Kääriö et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Circulating TSLP associates with decreased wheezing in non-atopic preschool children: data from the URECA birth cohort

(2014) S. Demehri et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Type-2 innate lymphoid cells in human allergic disease

(2014) Jillian L. Barlow et al.   Current Opinion in Allergy and Clinical Immunology

Recurrent wheeze and cough in young children: is it asthma?

(2014) CW Ng et al.   SINGAPORE MEDICAL JOURNAL

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood

(2013) Anna Lluis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Comparative analysis of circulating dendritic cell subsets in patients with atopic diseases and sarcoidosis

(2013) Yumeko Hayashi et al.   RESPIRATORY RESEARCH

Assessment of airflow limitation, airway inflammation, and symptoms during virus-induced wheezing episodes in 4- to 6-year-old children

(2012) George N. Konstantinou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The high affinity IgE receptor (FcεRI) expression and function in airway smooth muscle

(2012) Naresh Singh Redhu et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy

(2011) J. Liu et al.   ALLERGY

The Effect of Peptidoglycan Stimulation on Basophil-Mediated Atopic Responses During Pregnancy and in Newborns

(2011) Ling Yang et al.   JOURNAL OF ASTHMA

Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma

(2010) R. Alam et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma

(2010) Benny Dua et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker

(2010) Jing Liu et al.   PLoS One

Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing

(2009) John W. Upham et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impairment of T helper and T regulatory cell responses at birth

(2008) B. Schaub et al.   ALLERGY

Rhinovirus Disrupts the Barrier Function of Polarized Airway Epithelial Cells

(2008) Umadevi Sajjan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gene expression in CD4+ T-cells reflects heterogeneity in infant wheezing phenotypes

(2008) B. Kapitein et al.   EUROPEAN RESPIRATORY JOURNAL

Impairment of T-regulatory cells in cord blood of atopic mothers

(2008) Bianca Schaub et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 yr after severe respiratory syncytial virus bronchiolitis

(2008) Eli Silver et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood

(2008) J Henderson et al.   THORAX