An Acid-Free Deprotection of 5′-Amino-Modified Oligonucleotides

Chemistry, structure and function of approved oligonucleotide therapeutics

(2023) Martin Egli et al.   NUCLEIC ACIDS RESEARCH

The current landscape of nucleic acid therapeutics

(2021) Jayesh A. Kulkarni et al.   Nature Nanotechnology

Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug

(2020) Alexandre J. Debacker et al.   MOLECULAR THERAPY

A concise, modular antibody-oligonucleotide conjugation strategy based on disuccinimidyl ester activation chemistry

(2019) Gang Li et al.   CHEMBIOCHEM

Evaluation of the effect of 2′-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice

(2018) Thazha P. Prakash et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeted delivery of antisense oligonucleotides to pancreatic β-cells

(2018) C. Ämmälä et al.   Science Advances

Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials

(2016) Nicholas J Viney et al.   LANCET

Efficient Synthesis and Biological Evaluation of 5′-GalNAc Conjugated Antisense Oligonucleotides

(2015) Michael E. Østergaard et al.   BIOCONJUGATE CHEMISTRY

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice

(2014) Thazha P. Prakash et al.   NUCLEIC ACIDS RESEARCH

Mild Detritylation of Nucleic Acid Hydroxyl Groups by Warming Up

(2011) Jozef Salon et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Recent developments in oligonucleotide conjugation

(2010) Yashveer Singh et al.   CHEMICAL SOCIETY REVIEWS

Novel amino linkers enabling efficient labeling and convenient purification of amino-modified oligonucleotides

(2007) Yasuo Komatsu et al.   BIOORGANIC & MEDICINAL CHEMISTRY