Differential cell cycle checkpoint evasion by PTEN germline mutations associated with dichotomous phenotypes of cancer versus autism spectrum disorder
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Differential cell cycle checkpoint evasion by PTEN germline mutations associated with dichotomous phenotypes of cancer versus autism spectrum disorder
Authors
Keywords
-
Journal
ONCOGENE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-11-01
DOI
10.1038/s41388-023-02867-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- DNA damage response in neurodevelopment and neuromaintenance
- (2022) Xiaobing Qing et al. FEBS Journal
- Distinct metabolic profiles associated with autism spectrum disorder versus cancer in individuals with germline PTEN mutations
- (2022) Lamis Yehia et al. npj Genomic Medicine
- Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity
- (2021) Nick Sarn et al. Molecular Autism
- Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability
- (2020) Meiyan Wang et al. Cell Stem Cell
- An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships
- (2020) Taylor L. Mighell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- PTEN-opathies: from biological insights to evidence-based precision medicine
- (2019) Lamis Yehia et al. JOURNAL OF CLINICAL INVESTIGATION
- High‐throughput automated single‐cell imaging analysis reveals dynamics of glioblastoma stem cell population during state transition
- (2019) Anastasia P. Chumakova et al. CYTOMETRY PART A
- The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation
- (2019) Monique Bax et al. Cells
- A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships
- (2018) Taylor L. Mighell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer
- (2018) C Cruz et al. ANNALS OF ONCOLOGY
- Dynamics and structural stability effects of germline PTEN mutations associated with cancer versus autism phenotypes
- (2018) Iris Nira Smith et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Improving single-cell cloning workflow for gene editing in human pluripotent stem cells
- (2018) Yi-Hsien Chen et al. Stem Cell Research
- Cellular proteostasis: degradation of misfolded proteins by lysosomes
- (2016) M. P. Jackson et al. Essays in Biochemistry
- A recessive form of extreme macrocephaly and mild intellectual disability complements the spectrum of PTEN hamartoma tumour syndrome
- (2015) Tobias Schwerd et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder
- (2015) A K Tilot et al. MOLECULAR PSYCHIATRY
- Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function
- (2014) Antonella Papa et al. CELL
- AKT as a therapeutic target in multiple myeloma
- (2014) Niamh A Keane et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production
- (2014) A. K. Tilot et al. HUMAN MOLECULAR GENETICS
- PTEN Interacts with Histone H1 and Controls Chromatin Condensation
- (2014) Zhu Hong Chen et al. Cell Reports
- Cowden Syndrome-Related Mutations in PTEN Associate with Enhanced Proteasome Activity
- (2013) X. He et al. CANCER RESEARCH
- Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics Following Multiple Radiation Exposures
- (2013) Luca G. Mariotti et al. PLoS One
- PTEN Positively Regulates UVB-Induced DNA Damage Repair
- (2011) M. Ming et al. CANCER RESEARCH
- H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues
- (2011) Denis V. Firsanov et al. Clinical Epigenetics
- PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors
- (2010) B. McEllin et al. CANCER RESEARCH
- The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons
- (2010) Masahiro Hitomi et al. CYTOMETRY PART A
- Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53
- (2010) Xin He et al. HUMAN MOLECULAR GENETICS
- Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
- (2009) Sairei So et al. JOURNAL OF CELL BIOLOGY
- Phosphorylation of Cyclin D1 Regulated by ATM or ATR Controls Cell Cycle Progression
- (2008) M. Hitomi et al. MOLECULAR AND CELLULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started