Curcumin Induces Apoptosis by Suppressing XRCC4 Expression in Hepatocellular Carcinoma

Cancer statistics, 2023

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A novel combination of isovanillin, curcumin, and harmine (GZ17-6.02) enhances cell death and alters signaling in actinic keratoses cells when compared to individual components and two-component combinations

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Discovery of β-cyclocitral-derived mono-carbonyl curcumin analogs as anti-hepatocellular carcinoma agents via suppression of MAPK signaling pathway

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Curcumin in the treatment of liver cancer: From mechanisms of action to nanoformulations

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The Apoptosis of Liver Cancer Cells Promoted by Curcumin/TPP-CZL Nanomicelles With Mitochondrial Targeting Function

(2022) Wanyu Li et al.   Frontiers in Bioengineering and Biotechnology

Hepatocellular carcinoma

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A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma

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Genome stability‑related lncRNA ZFPM2‑AS1 promotes tumor progression via miR‑3065‑5p/XRCC4 in hepatocellular carcinoma

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Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Curcumin inhibits the growth of liver cancer by impairing myeloid‑derived suppressor cells in murine tumor tissues

(2021) Sha Tian et al.   Oncology Letters

EHMT2 promotes the pathogenesis of hepatocellular carcinoma by epigenetically silencing APC expression

(2021) Yuan Guo et al.   Cell and Bioscience

Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells

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Radiosensitizing Effect of Curcumin on Human Bladder Cancer Cell Lines: Impact on DNA Repair Mechanisms

(2021) Joyce Azzi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway

(2020) Ruiying Tong et al.   Oxidative Medicine and Cellular Longevity

DNA double-strand break repair-pathway choice in somatic mammalian cells

(2019) Ralph Scully et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genotypic analysis of XRCC4 and susceptibility to cervical cancer

(2019) MK Gupta et al.   BRITISH JOURNAL OF BIOMEDICAL SCIENCE

Curcumin induces DNA damage by mediating homologous recombination mechanism in triple negative breast cancer

(2019) Gamze Guney Eskiler et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling

(2018) Biqiong Ren et al.   ONCOLOGY REPORTS

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

An unexpected protein interaction promotes drug resistance in leukemia

(2017) Aaron Pitre et al.   Nature Communications

Lung cancer susceptibility and genetic polymorphism of DNA repair gene XRCC4 in Taiwan

(2017) Nan-Yung Hsu et al.   Cancer Biomarkers

Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA

(2016) Ineke Brouwer et al.   NATURE

Curcumin causes DNA damage and affects associated protein expression in HeLa human cervical cancer cells

(2016) Hung-Sheng Shang et al.   ONCOLOGY REPORTS

Curcumin inhibits cobalt chloride-induced epithelial-to-mesenchymal transition associated with interference with TGF-β/Smad signaling in hepatocytes

(2015) Desong Kong et al.   LABORATORY INVESTIGATION

Role of the functional variant (−652T>G) in the XRCC4 promoter in prostate cancer

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Enhancing Therapeutic Effects of Docetaxel-Loaded Dendritic Copolymer Nanoparticles by Co-Treatment with Autophagy Inhibitor on Breast Cancer

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Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor

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Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

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Curcumin: From ancient medicine to current clinical trials

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