Go-sha-jinki-Gan (GJG) ameliorates allodynia in chronic constriction injury model mice via suppression of TNF-α expression in the spinal cord

Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain

(2016) Ana C. Zarpelon et al.   FASEB JOURNAL

Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain

(2016) Toshiaki Suzuki et al.   JOURNAL OF ETHNOPHARMACOLOGY

Control of Neonatal Spinal Networks by Nociceptors: A Potential Role for TRP Channel Based Therapies

(2016) Sravan Mandadi et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Safety of Anti-Tumor Necrosis Factor Therapies in Arthritis Patients

(2016) Radu M Nanau et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study

(2015) Eiji Oki et al.   International Journal of Clinical Oncology

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Neuropathic Pain: Principles of Diagnosis and Treatment

(2015) Ian Gilron et al.   MAYO CLINIC PROCEEDINGS

Go-sha-jinki-Gan (GJG), a traditional Japanese herbal medicine, protects against sarcopenia in senescence-accelerated mice

(2015) Yuki Kishida et al.   PHYTOMEDICINE

σ1 receptors activate astrocytes via p38 MAPK phosphorylation leading to the development of mechanical allodynia in a mouse model of neuropathic pain

(2014) J Y Moon et al.   BRITISH JOURNAL OF PHARMACOLOGY

Surgical animal models of neuropathic pain: Pros and Cons

(2014) Siva Reddy Challa   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Goshajinkigan, a Traditional Japanese Medicine, Prevents Oxaliplatin-Induced Acute Peripheral Neuropathy by Suppressing Functional Alteration of TRP Channels in Rat

(2014) Keita Mizuno et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The Prophylactic Effects of a Traditional Japanese Medicine, Goshajinkigan, on Paclitaxel-Induced Peripheral Neuropathy and its Mechanism of Action

(2014) Yukiko Matsumura et al.   Molecular Pain

An Active Component of Achyranthes bidentata Polypeptides Provides Neuroprotection through Inhibition of Mitochondrial-Dependent Apoptotic Pathway in Cultured Neurons and in Animal Models of Cerebral Ischemia

(2014) Shu Yu et al.   PLoS One

Management of chronic neuropathic pain: a protocol for a multiple treatment comparison meta-analysis of randomised controlled trials

(2014) Sohail M Mulla et al.   BMJ Open

Gosha-jinki-gan reduced oxaliplatin-induced hypersensitivity to cold sensation and its effect would be related to suppression of the expression of TRPM8 and TRPA1 in rats

(2013) Yoshinori Kato et al.   ANTI-CANCER DRUGS

Anti-diabetic Action of 7-O-Galloyl-d-sedoheptulose, a Polyphenol from Corni Fructus, through Ameliorating Inflammation and Inflammation-Related Oxidative Stress in the Pancreas of Type 2 Diabetics

(2013) Chan Hum Park et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy

(2013) Toru Kono et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pain Management in Older Adults

(2013) Bridget Tracy et al.   CLINICAL THERAPEUTICS

Importance of glial activation in neuropathic pain

(2013) Joanna Mika et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Herbal Medicine Goshajinkigan Prevents Paclitaxel-Induced Mechanical Allodynia without Impairing Antitumor Activity of Paclitaxel

(2013) Muh. Akbar Bahar et al.   Evidence-based Complementary and Alternative Medicine

Antioxidant and anti-inflammatory properties of taiwanese yam (Dioscorea japonica Thunb. var. pseudojaponica (Hayata) Yamam.) and its reference compounds

(2013) Chuan-Sung Chiu et al.   FOOD CHEMISTRY

The anti-inflammation effect of Moutan Cortex on advanced glycation end products-induced rat mesangial cells dysfunction and High-glucose–fat diet and streptozotocin-induced diabetic nephropathy rats

(2013) Ming-hua Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuropathische Schmerzen

(2013) C. Sommer   SCHMERZ

Analgesic use in the older person

(2013) Gisèle Pickering   Current Opinion in Supportive and Palliative Care

Efficacy of Goshajinkigan for Oxaliplatin-Induced Peripheral Neuropathy in Colorectal Cancer Patients

(2013) Naohisa Yoshida et al.   Journal of Oncology

Anti-Inflammatory Activities ofCinnamomum cassiaConstituentsIn VitroandIn Vivo

(2012) Jung-Chun Liao et al.   Evidence-based Complementary and Alternative Medicine

Bioassay-guided isolation of anti-inflammatory components from the root of Rehmannia glutinosa and its underlying mechanism via inhibition of iNOS pathway

(2012) Cheuk-Lun Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

Moutan cortex radicis improves lipopolysaccharide-induced acute lung injury in rats through anti-inflammation

(2012) Pin-Kuei Fu et al.   PHYTOMEDICINE

Hot Water Extracted Lycium Barbarum and Rehmannia Glutinosa Inhibit Liver Inflammation and Fibrosis in Rats

(2011) Po-Shan Wu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Evaluation of Morroniside, Iridoid Glycoside from Corni Fructus, on Diabetes-Induced Alterations such as Oxidative Stress, Inflammation, and Apoptosis in the Liver of Type 2 Diabetic db/db Mice

(2011) Chan Hum Park et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Traditional Japanese medicine, Kampo: Its history and current status

(2011) Yoshiharu Motoo et al.   Chinese Journal of Integrative Medicine

Effect of Three Types of Mixed Anesthetic Agents Alternate to Ketamine in Mice

(2011) Sumiko KAWAI et al.   EXPERIMENTAL ANIMALS

The Astrocyte-Targeted Therapy by Bushi for the Neuropathic Pain in Mice

(2011) Keisuke Shibata et al.   PLoS One

TNF-α and neuropathic pain - a review

(2010) Lawrence Leung et al.   Journal of Neuroinflammation

Interactions between the immune and nervous systems in pain

(2010) Ke Ren et al.   NATURE MEDICINE

Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats

(2010) Merab G. Tsagareli et al.   NEUROSCIENCE LETTERS

The protective effects of Achyranthes bidentata polypeptides in an experimental model of mouse sciatic nerve crush injury

(2009) Ying Yuan et al.   BRAIN RESEARCH BULLETIN

JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain

(2009) Y.-J. Gao et al.   JOURNAL OF NEUROSCIENCE

The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation

(2009) Diogo Santos M. da Costa et al.   PAIN

Prolonged Survival of Fully Mismatched Cardiac Allografts and Generation of Regulatory Cells by Sairei-to, a Japanese Herbal Medicine

(2009) Qi Zhang et al.   TRANSPLANTATION

Chemokines and pain mechanisms

(2008) Catherine Abbadie et al.   BRAIN RESEARCH REVIEWS

Neuron–glia crosstalk gets serious: role in pain hypersensitivity

(2008) Ke Ren et al.   Current Opinion in Anesthesiology

Ultraviolet A induced modulation of gap junctional intercellular communication by P38 MAPK activation in human keratinocytes

(2008) Barbara Bellei et al.   EXPERIMENTAL DERMATOLOGY

β2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain

(2008) Ipek Yalcin et al.   NEUROBIOLOGY OF DISEASE

Early cytokine gene expression in mouse CNS after peripheral nerve lesion

(2008) Nurcan Üçeyler et al.   NEUROSCIENCE LETTERS