Heme acquisition mechanisms ofPorphyromonas gingivalis- strategies used in a polymicrobial community in a heme-limited host environment

HmuY is an important virulence factor for Porphyromonas gingivalis growth in the heme-limited host environment and infection of macrophages

(2015) Teresa Olczak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of amino acid residues involved in hemin binding inPorphyromonas gingivalishemagglutinin 2

(2015) Q.B. Yang et al.   Molecular Oral Microbiology

Pyocycanin, a Contributory Factor in Haem Acquisition and Virulence Enhancement of Porphyromonas gingivalis in the Lung

(2015) Malgorzata Benedyk et al.   PLoS One

Molecular Structures and Solvation of Free Monomeric and Dimeric Ferriheme in Aqueous Solution: Insights from Molecular Dynamics Simulations and Extended X-ray Absorption Fine Structure Spectroscopy

(2014) David Kuter et al.   INORGANIC CHEMISTRY

Structure and Mechanism of Cysteine Peptidase Gingipain K (Kgp), a Major Virulence Factor ofPorphyromonas gingivalisin Periodontitis

(2014) Iñaki de Diego et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Porphyromonas gingivalisand related bacteria: from colonial pigmentation to the type IX secretion system and gliding motility

(2014) K. Nakayama   JOURNAL OF PERIODONTAL RESEARCH

16S rDNA-based metagenomic analysis of dental plaque and lung bacteria in patients with severe acute exacerbations of chronic obstructive pulmonary disease

(2014) L. Tan et al.   JOURNAL OF PERIODONTAL RESEARCH

Porphyromonas gingivalis Outer Membrane Vesicles Exclusively Contain Outer Membrane and Periplasmic Proteins and Carry a Cargo Enriched with Virulence Factors

(2014) Paul D. Veith et al.   JOURNAL OF PROTEOME RESEARCH

Fur homolog regulatesPorphyromonas gingivalisvirulence under low-iron/heme conditions through a complex regulatory network

(2014) J. Ciuraszkiewicz et al.   Molecular Oral Microbiology

Structure of the lysine specific protease Kgp fromPorphyromonas gingivalis, a target for improved oral health

(2014) Michael A. Gorman et al.   PROTEIN SCIENCE

Genome of the pathogen Porphyromonas gingivalis recovered from a biofilm in a hospital sink using a high-throughput single-cell genomics platform

(2013) J. S. McLean et al.   GENOME RESEARCH

Porphyromonas gingivalisVirulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases

(2013) Iñaki de Diego et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Porphyromonas gingivalis HmuY haemophore binds gallium(iii), zinc(ii), cobalt(iii), manganese(iii), nickel(ii), and copper(ii) protoporphyrin IX but in a manner different to iron(iii) protoporphyrin IX

(2013) Halina Wójtowicz et al.   Metallomics

A Two-Component System Regulates Hemin Acquisition in Porphyromonas gingivalis

(2013) Jodie C. Scott et al.   PLoS One

Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen

(2012) Nagihan Bostanci et al.   FEMS MICROBIOLOGY LETTERS

The Role of Heme Binding by DNA-protective Protein from Starved Cells (Dps) in the Tolerance ofPorphyromonas gingivalisto Heme Toxicity

(2012) Jin-Long Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Haemophore functions revisited

(2012) Cécile Wandersman et al.   MOLECULAR MICROBIOLOGY

Evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the HmuY haemophore ofPorphyromonas gingivalisand the cysteine protease interpain A (InpA) ofPrevotella intermedia

(2012) D.P. Byrne et al.   Molecular Oral Microbiology

Pseudomonas aeruginosaPopulation Diversity and Turnover in Cystic Fibrosis Chronic Infections

(2011) Eilidh Mowat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Colocalization of Porphyromonas gingivalis with CD4+ T cells in periodontal disease

(2011) Helene Guyodo et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Complete Genome Sequence of the Bacterium Porphyromonas gingivalis TDC60, Which Causes Periodontal Disease

(2011) T. Watanabe et al.   JOURNAL OF BACTERIOLOGY

Induction of interleukin (IL)-1β, IL-10, IL-8 and immunoglobulin G by Porphyromonas gingivalis HmuY in humans

(2011) S. C. Trindade et al.   JOURNAL OF PERIODONTAL RESEARCH

The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis

(2011) Nan Li et al.   MOLECULAR MICROBIOLOGY

HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis

(2011) John W. Smalley et al.   PLoS One

Por Secretion System-Dependent Secretion and Glycosylation of Porphyromonas gingivalis Hemin-Binding Protein 35

(2011) Mikio Shoji et al.   PLoS One

Species specificity, surface exposure, protein expression, immunogenicity, and participation in biofilm formation of Porphyromonas gingivalis HmuY

(2010) Teresa Olczak et al.   BMC MICROBIOLOGY

Characterization of hemin-binding protein 35 (HBP35) in Porphyromonas gingivalis: its cellular distribution, thioredoxin activity and role in heme utilization

(2010) Mikio Shoji et al.   BMC MICROBIOLOGY

Putative respiratory chain ofPorphyromonas gingivalis

(2010) Vincent Meuric et al.   Future Microbiology

Characterization of a Hemophore-like Protein fromPorphyromonas gingivalis

(2010) Jin-Long Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hemin-binding protein 35 (HBP35) plays an important role in bacteria–mammalian cells interactions in Porphyromonas gingivalis

(2010) Koichi Hiratsuka et al.   MICROBIAL PATHOGENESIS

Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis

(2010) Nan Li et al.   MOLECULAR MICROBIOLOGY

Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon’s knife to a meat chopper-like brutal degradation of proteins

(2010) Yonghua Guo et al.   PERIODONTOLOGY 2000

Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

(2010) M. Ulrich et al.   THORAX

Heme environment in HmuY, the heme-binding protein of Porphyromonas gingivalis

(2009) Halina Wójtowicz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of the cysteine protease interpain A ofPrevotella intermediain breakdown and release of haem from haemoglobin

(2009) Dominic P. Byrne et al.   BIOCHEMICAL JOURNAL

Structural Characterization of the Hemophore HasAp fromPseudomonas aeruginosa: NMR Spectroscopy Reveals Protein−Protein Interactions between Holo-HasAp and Hemoglobin†,‡

(2009) Aileen Y. Alontaga et al.   BIOCHEMISTRY

Speciation of Ferriprotoporphyrin IX in Aqueous and Mixed Aqueous Solution Is Controlled by Solvent Identity, pH, and Salt Concentration

(2009) Constance Asher et al.   INORGANIC CHEMISTRY

Neutralization of toxic haem by Porphyromonas gingivalis haemoglobin receptor

(2009) Nguyen Thanh Thuy Nhien et al.   JOURNAL OF BIOCHEMISTRY

Subgingival biofilm formation

(2009) Masae Kuboniwa et al.   PERIODONTOLOGY 2000

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex

(2009) S. Krieg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the heme/hemoglobin outer membrane receptor ShuA fromShigella dysenteriae: Heme binding by an induced fit mechanism

(2009) David Cobessi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

(2009) Halina Wójtowicz et al.   PLoS Pathogens

Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis

(2008) Michael M. Tunney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis

(2008) John W. Smalley et al.   BIOLOGICAL CHEMISTRY

Functional Analysis of the Thioredoxin Domain inPorphyromonas gingivalisHBP35

(2008) Teruaki SHIROZA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Determination of the Genome Sequence of Porphyromonas gingivalis Strain ATCC 33277 and Genomic Comparison with Strain W83 Revealed Extensive Genome Rearrangements in P. gingivalis

(2008) M. Naito et al.   DNA RESEARCH

Role of the hemin-binding protein 35 (HBP35) of Porphyromonas gingivalis in coaggregation

(2007) Koichi Hiratsuka et al.   MICROBIAL PATHOGENESIS