Phosphorylated Ser187-SNAP25-modulated hyperfunction of glutamatergic system in the vmPFC mediates depressive-like behaviors in male mice

Social isolation after chronic unpredictable mild stress perpetuates depressive-like behaviors, memory deficits and social withdrawal via inhibiting ERK/KEAP1/NRF2 signaling

(2022) Lujia Si et al.   JOURNAL OF AFFECTIVE DISORDERS

Amygdala-hippocampal innervation modulates stress-induced depressive-like behaviors through AMPA receptors

(2021) Hui Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation

(2021) Roger S. McIntyre et al.   AMERICAN JOURNAL OF PSYCHIATRY

Glutamate: The Master Neurotransmitter and Its Implications in Chronic Stress and Mood Disorders

(2021) Mia Michaela Pal   Frontiers in Human Neuroscience

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

(2021) Damian F Santomauro et al.   LANCET

Targeting the dysfunction of glutamate receptors for the development of novel antidepressants

(2021) Cong-Yuan Xia et al.   PHARMACOLOGY & THERAPEUTICS

Chronic stress followed by social isolation promotes depressive-like behaviour, alters microglial and astrocyte biology and reduces hippocampal neurogenesis in male mice

(2020) Andrea Du Preez et al.   BRAIN BEHAVIOR AND IMMUNITY

Modulation by chronic stress and ketamine of ionotropic AMPA/NMDA and metabotropic glutamate receptors in the rat hippocampus

(2020) Mohammed E.A. Elhussiny et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions

(2019) Manoela V. Fogaça et al.   Frontiers in Cellular Neuroscience

SNAP-25 in Major Psychiatric Disorders: A Review

(2019) Katherine Najera et al.   NEUROSCIENCE

Metabolic and proteomic alteration in phytohormone-producing endophytic Bacillus amyloliquefaciens RWL-1 during methanol utilization

(2019) Raheem Shahzad et al.   Metabolomics

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

(2019) Ronald S. Duman et al.   NEURON

Medial prefrontal cortex in neurological diseases

(2019) Pan Xu et al.   PHYSIOLOGICAL GENOMICS

The role of NMDA receptor in neurobiology and treatment of major depressive disorder: Evidence from translational research

(2019) Meysam Amidfar et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Involvement of SNARE complex in the hippocampus and prefrontal cortex of offspring with depression induced by prenatal stress

(2018) Yan Jun Cao et al.   JOURNAL OF AFFECTIVE DISORDERS

The SNAP-25 protein family

(2018) Anna Kádková et al.   NEUROSCIENCE

Depression

(2018) Gin S Malhi et al.   LANCET

Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies

(2018) Sho Moriguchi et al.   MOLECULAR PSYCHIATRY

Chronic Unpredictable Mild Stress for Modeling Depression in Rodents:Meta-analysis of Model Reliability

(2018) Svitlana Antoniuk et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Targeting glutamate signalling in depression: progress and prospects

(2017) James W. Murrough et al.   NATURE REVIEWS DRUG DISCOVERY

The Role of Neural Plasticity in Depression: From Hippocampus to Prefrontal Cortex

(2017) Wei Liu et al.   NEURAL PLASTICITY

Differential role of SNAP-25 phosphorylation by protein kinases A and C in the regulation of SNARE complex formation and exocytosis in PC12 cells

(2016) Jing Gao et al.   CELLULAR SIGNALLING

Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity

(2016) Danielle M. Gerhard et al.   DRUG DISCOVERY TODAY

SNARE complex in developmental psychiatry: neurotransmitter exocytosis and beyond

(2016) Renata Basso Cupertino et al.   JOURNAL OF NEURAL TRANSMISSION

Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice

(2016) F. Higuchi et al.   JOURNAL OF NEUROSCIENCE

SNAP25 Is Associated With Schizophrenia and Major Depressive Disorder in the Han Chinese Population

(2015) Qingzhong Wang et al.   JOURNAL OF CLINICAL PSYCHIATRY

Stress-induced phosphorylation of SNAP-25

(2014) Saori Yamamori et al.   NEUROSCIENCE LETTERS

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

(2012) Vanja Duric et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm

(2011) C. Kiselycznyk et al.   NEUROSCIENCE

SNAP-25 Is a Target of Protein Kinase C Phosphorylation Critical to NMDA Receptor Trafficking

(2010) C. G. Lau et al.   JOURNAL OF NEUROSCIENCE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

The functional neuroanatomy of depression: Distinct roles for ventromedial and dorsolateral prefrontal cortex

(2009) Michael Koenigs et al.   BEHAVIOURAL BRAIN RESEARCH

The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression

(2009) Esra Küçükibrahimoğlu et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY