Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

(2016) Raphael Bueno et al.   NATURE GENETICS

Searching for targets for the systemic therapy of mesothelioma

(2015) R. A. Stahel et al.   ANNALS OF ONCOLOGY

Hippo Pathway Gene Mutations in Malignant Mesothelioma: Revealed by RNA and Targeted Exon Sequencing

(2015) Akihiko Miyanaga et al.   Journal of Thoracic Oncology

Targeted Next-Generation Sequencing of Cancer Genes in Advanced Stage Malignant Pleural Mesothelioma: A Retrospective Study

(2015) Marco Lo Iacono et al.   Journal of Thoracic Oncology

A New Prognostic Score Supporting Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma

(2015) Isabelle Opitz et al.   Journal of Thoracic Oncology

Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus

(2014) Wei Li et al.   CANCER CELL

Significant Association of Oncogene YAP1 with Poor Prognosis and Cetuximab Resistance in Colorectal Cancer Patients

(2014) K.-W. Lee et al.   CLINICAL CANCER RESEARCH

Evaluation of imaging techniques for the assessment of tumour progression in an orthotopic rat model of malignant pleural mesothelioma†

(2014) Mayura Meerang et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

PI3K/mTOR Signaling in Mesothelioma Patients Treated with Induction Chemotherapy Followed by Extrapleural Pneumonectomy

(2014) Byron K.Y. Bitanihirwe et al.   Journal of Thoracic Oncology

Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

(2014) I. M. Shapiro et al.   Science Translational Medicine

Is survivin expression prognostic or predictive in malignant pleural mesothelioma?

(2013) Julija Hmeljak et al.   VIRCHOWS ARCHIV

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus

(2012) Wei Li et al.   EMBO REPORTS

TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth

(2012) Makiko Fujii et al.   JOURNAL OF EXPERIMENTAL MEDICINE

YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes

(2012) T Mizuno et al.   ONCOGENE

LATS2 Is a Tumor Suppressor Gene of Malignant Mesothelioma

(2011) H. Murakami et al.   CANCER RESEARCH

Global Magnitude of Reported and Unreported Mesothelioma

(2011) Eun-Kee Park et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mammalian Hippo pathway: from development to cancer and beyond

(2011) Y. Bao et al.   JOURNAL OF BIOCHEMISTRY

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

(2011) Matthew Bott et al.   NATURE GENETICS

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

(2010) Wei Li et al.   CELL

Malignant pleural mesothelioma: The standard of care and challenges for future management

(2010) Jan P. van Meerbeeck et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: An exploratory analysis

(2010) Roy Sidi et al.   EUROPEAN JOURNAL OF CANCER

Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: A phase II prospective study

(2009) Tamara R. Tilleman et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth

(2009) M. F. James et al.   MOLECULAR AND CELLULAR BIOLOGY

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Functional inactivation of NF2/merlin in human mesothelioma

(2008) Claudio Thurneysen et al.   LUNG CANCER