Sesamol supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of nuclear factor kappaB

NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease

(2016) Viviana Triaca et al.   AGING CELL

d-Allulose supplementation normalized the body weight and fat-pad mass in diet-induced obese mice via the regulation of lipid metabolism under isocaloric fed condition

(2016) Youngji Han et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway

(2016) Haroon Badshah et al.   Scientific Reports

Molecular Mechanisms Regulating LPS-Induced Inflammation in the Brain

(2016) Olena Lykhmus et al.   Frontiers in Molecular Neuroscience

Neuroprotective potential of sesamol and its loaded solid lipid nanoparticles in ICV-STZ-induced cognitive deficits: Behavioral and biochemical evidence

(2015) Anand Kamal Sachdeva et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sesamol suppresses the inflammatory response by inhibiting NF-κB/MAPK activation and upregulating AMP kinase signaling in RAW 264.7 macrophages

(2015) Xin-Ling Wu et al.   INFLAMMATION RESEARCH

Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway

(2015) Sun Mi Gu et al.   Journal of Neuroinflammation

Sesamol Ameliorates Cyclophosphamide-Induced Hepatotoxicity by Modulating Oxidative Stress and Inflammatory Mediators

(2014) S. Jnaneshwari et al.   Anti-Cancer Agents in Medicinal Chemistry

The interaction of sesamol with DNA and cytotoxicity, apoptosis, and localization in HepG2 cells

(2013) Zhigang Liu et al.   FOOD CHEMISTRY

Age-Dependent Modulation of Synaptic Plasticity and Insulin Mimetic Effect of Lipoic Acid on a Mouse Model of Alzheimer’s Disease

(2013) Harsh Sancheti et al.   PLoS One

Implication of NGF and endocannabinoid signaling in the mechanism of action of sesamol: a multi-target natural compound with therapeutic potential

(2013) Parichehr Hassanzadeh et al.   PSYCHOPHARMACOLOGY

Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathway

(2012) Yan Qiao et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models

(2012) Young-Jung Lee et al.   Journal of Neuroinflammation

GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia

(2012) Bijay Parajuli et al.   Journal of Neuroinflammation

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

(2012) Young-Jung Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sesamol: An Efficient Antioxidant with Potential Therapeutic Benefits

(2012) Thiraviam Geetha et al.   Medicinal Chemistry

Progressive cholinergic decline in Alzheimer's Disease: consideration for treatment with donepezil 23 mg in patients with moderate to severe symptomatology

(2011) Marwan Sabbagh et al.   BMC Neurology

Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: Multiplex quantification with path analysis

(2011) Michelle A. Erickson et al.   BRAIN BEHAVIOR AND IMMUNITY

Matrix metalloproteinase-9 and non-amyloidogenic pathway of amyloid precursor protein processing

(2011) Mikhail A. Filippov et al.   JOURNAL OF NEUROCHEMISTRY

Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway

(2011) Dong-Young Choi et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

Toll-like receptor signaling in neural plasticity and disease

(2011) Eitan Okun et al.   TRENDS IN NEUROSCIENCES

Protective Effect of Sesamol against 3-Nitropropionic Acid-Induced Cognitive Dysfunction and Altered Glutathione Redox Balance in Rats

(2010) Puneet Kumar et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The history of the cholinergic hypothesis

(2010) Antonio Contestabile   BEHAVIOURAL BRAIN RESEARCH

Sesamol Suppresses Neuro-Inflammatory Cascade in Experimental Model of Diabetic Neuropathy

(2010) Kanwaljit Chopra et al.   JOURNAL OF PAIN

Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences

(2010) Baldeep Kumar et al.   PSYCHOPHARMACOLOGY

The non-peptide chemical 3,4-methylenedioxyphenol blocked lipopolysaccharide (LPS) from binding to LPS-binding protein and inhibited pro-inflammatory cytokines

(2009) Dur-Zong Hsu et al.   Innate Immunity

Sesamol down-regulates the lipopolysaccharide-induced inflammatory response by inhibiting nuclear factor-kappa B activation

(2009) Pei-Yi Chu et al.   Innate Immunity

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

The brain expression of genes involved in inflammatory response, the ribosome and learning and memory is altered by centrally injected lipopolysaccharide in mice

(2008) R H Bonow et al.   PHARMACOGENOMICS JOURNAL

NGF and BDNF signaling control amyloidogenic route and A  production in hippocampal neurons

(2008) C. Matrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA