Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs

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The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion

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Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

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SOX10 Transactivates S100B to Suppress Schwann Cell Proliferation and to Promote Myelination

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Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

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Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas

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Sox10is required for Schwann cell identity and progression beyond the immature Schwann cell stage

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Evidence of a four-hit mechanism involvingSMARCB1andNF2in schwannomatosis-associated schwannomas

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