Generation of quality-controlled SARS-CoV-2 variant stocks

A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8

(2023) Bruno A. Rodriguez-Rodriguez et al.   Nature Communications

Delta-Omicron recombinant escapes therapeutic antibody neutralization

(2023) Ralf Duerr et al.   iScience

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

(2022) M. Zeeshan Chaudhry et al.   JOURNAL OF VIROLOGY

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity

(2022) Bo Meng et al.   NATURE

Robust immune responses are observed after one dose of BNT162b2 mRNA vaccine dose in SARS-CoV-2–experienced individuals

(2022) Marie I. Samanovic et al.   Science Translational Medicine

Development and validation of a high throughput SARS-CoV-2 whole genome sequencing workflow in a clinical laboratory

(2022) Sun Hee Rosenthal et al.   Scientific Reports

Isolation of SARS-CoV-2 in Viral Cell Culture in Immunocompromised Patients With Persistently Positive RT-PCR Results

(2022) Abby Sung et al.   Frontiers in Cellular and Infection Microbiology

A Defective Viral Particle Approach to COVID-19

(2022) Maria Kalamvoki et al.   Cells

Cellular and Humoral Immunity to SARS‐CoV‐2 Infection in Multiple Sclerosis Patients on Ocrelizumab and Other Disease‐Modifying Therapies: A Multi‐Ethnic Observational Study

(2022) Ilya Kister et al.   ANNALS OF NEUROLOGY

SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses

(2022) Maaike C Swets et al.   LANCET

Replication kinetics and infectivity of SARS-CoV-2 variants of concern in common cell culture models

(2022) Lena Mautner et al.   Virology Journal

QTQTN motif upstream of the furin-cleavage site plays a key role in SARS-CoV-2 infection and pathogenesis

(2022) Michelle N. Vu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

(2022) Brian J. Willett et al.   Nature Microbiology

SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesis

(2022) Marisa E. McGrath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural Studies

(2022) Zlatka Plavec et al.   Viruses-Basel

Detection and prevalence of SARS-CoV-2 co-infections during the Omicron variant circulation in France

(2022) Antonin Bal et al.   Nature Communications

Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

(2022) Lucie Bernard-Raichon et al.   Nature Communications

Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways

(2022) Naoko Iwata-Yoshikawa et al.   Nature Communications

ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection

(2022) Krystal L. Ching et al.   PLOS BIOLOGY

Hybrid and vaccine‐induced immunity against SAR‐CoV ‐2 in MS patients on different disease‐modifying therapies

(2022) Ilya Kister et al.   Annals of Clinical and Translational Neurology

Evolution of naturally arising SARS-CoV-2 defective interfering particles

(2022) Samer Girgis et al.   Communications Biology

Vaccine-Acquired SARS-CoV-2 Immunity versus Infection-Acquired Immunity: A Comparison of Three COVID-19 Vaccines

(2022) Marie I. Samanovic et al.   Vaccines

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

(2021) Bryan A. Johnson et al.   NATURE

SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells

(2021) Michihito Sasaki et al.   PLoS Pathogens

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

(2021) Jennifer Gribble et al.   PLoS Pathogens

SARS-CoV-2 Respiratory Co-Infections: Incidence of Viral and Bacterial Co-Pathogens

(2021) Vijay Singh et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19

(2021) Maren de Vries et al.   JOURNAL OF VIROLOGY

Engineering SARS-CoV-2 using a reverse genetic system

(2021) Xuping Xie et al.   Nature Protocols

Optimal preparation of SARS-CoV-2 viral transport medium for culture

(2021) Julie McAuley et al.   Virology Journal

Evaluation of PCR Cycle Threshold Values by Patient Population with the Quidel Lyra SARS-CoV-2 Assay

(2021) Robert F. Potter et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

An in vitro model for assessment of SARS-CoV-2 infectivity by defining the correlation between virus isolation and quantitative PCR value: isolation success of SARS-CoV-2 from oropharyngeal swabs correlates negatively with Cq value

(2021) Sissy Therese Sonnleitner et al.   Virology Journal

The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways

(2021) Manon Laporte et al.   PLoS Pathogens

Genetic Mutation of SARS-CoV-2 during Consecutive Passages in Permissive Cells

(2021) Ying Chen et al.   VIROLOGICA SINICA

TMPRSS2 expression dictates the entry route used by SARS‐CoV‐2 to infect host cells

(2021) Jana Koch et al.   EMBO JOURNAL

Evaluation of Immune Response and Disease Status in SLE Patients Following SARS‐CoV‐2 Vaccination

(2021) Peter M. Izmirly et al.   Arthritis & Rheumatology

A cautionary perspective regarding the isolation and serial propagation of SARS-CoV-2 in Vero cells

(2021) Simon G. P. Funnell et al.   npj Vaccines

SARS-CoV-2 Quasispecies Provides an Advantage Mutation Pool for the Epidemic Variants

(2021) Fengming Sun et al.   Microbiology Spectrum

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study

(2021) Clark D Russell et al.   Lancet Microbe

The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target

(2021) Gergely Rona et al.   CELL DEATH AND DIFFERENTIATION

Proteolytic activation of SARS‐CoV‐2 spike protein

(2021) Makoto Takeda   MICROBIOLOGY AND IMMUNOLOGY

Mechanisms of SARS-CoV-2 entry into cells

(2021) Cody B. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Propagation of SARS-CoV-2 in Calu-3 Cells to Eliminate Mutations in the Furin Cleavage Site of Spike

(2021) John James Baczenas et al.   Viruses-Basel

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

(2020) Shutoku Matsuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards

(2020) Bernard La Scola et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

College of American Pathologists (CAP) Microbiology Committee Perspective: Caution Must Be Used in Interpreting the Cycle Threshold (Ct) Value

(2020) Daniel Rhoads et al.   CLINICAL INFECTIOUS DISEASES

High-speed large-scale automated isolation of SARS-CoV-2 from clinical samples using miniaturized co-culture coupled to high-content screening

(2020) Rania Francis et al.   CLINICAL MICROBIOLOGY AND INFECTION

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients

(2020) William B. Klimstra et al.   JOURNAL OF GENERAL VIROLOGY

Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.

(2020) Kumari G. Lokugamage et al.   JOURNAL OF VIROLOGY

Growth, detection, quantification, and inactivation of SARS-CoV-2

(2020) James Brett Case et al.   VIROLOGY

The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV

(2020) Mihkel Örd et al.   Scientific Reports

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model

(2017) Minna M. Hankaniemi et al.   VACCINE

Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses

(2016) Shuo Su et al.   TRENDS IN MICROBIOLOGY

Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

(2013) T. Scobey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Cryopreservation and banking of mammalian cell lines

(2009) Glyn N Stacey et al.   Nature Protocols