Thiol-catalyzed formation of NO-ferroheme regulates intravascular NO signaling

HRG-9 homologues regulate haem trafficking from haem-enriched compartments

(2022) Fengxiu Sun et al.   NATURE

Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure

(2021) Francesca Leo et al.   CIRCULATION

Nitric oxide and heme-NO stimulate superoxide production by NADPH oxidase 5

(2021) Elizabeth A. Sweeny et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endogenous Hemoprotein-Dependent Signaling Pathways of Nitric Oxide and Nitrite

(2021) Matthew R. Dent et al.   INORGANIC CHEMISTRY

Heme-Derived Metabolic Signals Dictate Immune Responses

(2020) Giacomo Canesin et al.   Frontiers in Immunology

GAPDH Delivers Heme to Soluble Guanylyl Cyclase

(2020) Yue Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The solution chemistry of nitric oxide and other reactive nitrogen species

(2020) Peter C. Ford et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

One ring to bring them all and in the darkness bind them: The trafficking of heme without deliverers

(2020) Ian G. Chambers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glutathione and the intracellular labile heme pool

(2020) Rosemary O’Keeffe et al.   BIOMETALS

Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition

(2019) Maya Shvartsman et al.   Scientific Reports

Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and QM/MM Theoretical Investigations into Preferred Fe–NO Ligand Orientations in Myoglobin Distal Pockets

(2018) Bing Wang et al.   BIOCHEMISTRY

Nitrite and nitrate chemical biology and signaling

(2018) Anthony W DeMartino et al.   BRITISH JOURNAL OF PHARMACOLOGY

Handling heme: The mechanisms underlying the movement of heme within and between cells

(2018) Rebecca K. Donegan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Erythrocytic bioactivation of nitrite and its potentiation by far-red light

(2018) Nadeem Wajih et al.   Redox Biology

The NO-heme signaling hypothesis

(2017) Andrei L. Kleschyov   FREE RADICAL BIOLOGY AND MEDICINE

Conjugated Linoleic Acid Modulates Clinical Responses to Oral Nitrite and NitrateNovelty and Significance

(2017) Kara S. Hughan et al.   HYPERTENSION

Potential therapeutic action of nitrite in sickle cell disease

(2017) Nadeem Wajih et al.   Redox Biology

Ferriheme catalyzes nitric oxide reaction with glutathione to form S-nitrosoglutathione: A novel mechanism for formation of S-nitrosothiols

(2016) Enika Nagababu   FREE RADICAL BIOLOGY AND MEDICINE

A mathematical model for the role of N 2 O 3 in enhancing nitric oxide bioavailability following nitrite infusion

(2016) Yien Liu et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors

(2016) David A. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of red blood cell S-nitrosation in nitrite bioactivation and its modulation by leucine and glucose

(2016) Nadeem Wajih et al.   Redox Biology

Red Blood Cell Membrane-Facilitated Release of Nitrite-Derived Nitric Oxide Bioactivity

(2015) Maria T. Salgado et al.   BIOCHEMISTRY

Heme as a danger molecule in pathogen recognition

(2015) Barbara Wegiel et al.   FREE RADICAL BIOLOGY AND MEDICINE

The ins and outs of erythroid heme transport

(2015) C. Cao et al.   HAEMATOLOGICA

The ins and outs of erythroid heme transport

(2015) C. Cao et al.   HAEMATOLOGICA

In Situ Microparticles Loaded with S-Nitrosoglutathione Protect from Stroke

(2015) Marianne Parent et al.   PLoS One

Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

(2014) Deborah Chiabrando et al.   Frontiers in Pharmacology

Endothelial nitric oxide synthase in red blood cells: Key to a new erythrocrine function?

(2014) Miriam M. Cortese-Krott et al.   Redox Biology

The concentration of glutathione in human erythrocytes is a heritable trait

(2013) Thomas J. van ‘t Erve et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitrite Reduction Mediated by Heme Models. Routes to NO and HNO?

(2013) Julie L. Heinecke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

(2012) Adam C. Straub et al.   NATURE

Methaemalbumin formation in sickle cell disease: effect on oxidative protein modification and HO-1 induction

(2011) Madelyn S. Hanson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hemoglobin as a Nitrite Anhydrase: Modeling Methemoglobin-Mediated N2O3 Formation

(2011) Kathrin H. Hopmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

Electronic Structure of Heme-Nitrosyls and Its Significance for Nitric Oxide Reactivity, Sensing, Transport, and Toxicity in Biological Systems

(2010) Lauren E. Goodrich et al.   INORGANIC CHEMISTRY

Reactions of NO and Nitrite with Heme Models and Proteins

(2010) Peter C. Ford   INORGANIC CHEMISTRY

Nitric oxide at a glance

(2010) Khalid M. Naseem et al.   PLATELETS

Ibuprofen modulates allosterically NO dissociation from ferrous nitrosylated human serum heme-albumin by binding to three sites

(2009) Paolo Ascenzi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Abacavir and warfarin modulate allosterically kinetics of NO dissociation from ferrous nitrosylated human serum heme-albumin

(2008) Paolo Ascenzi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes

(2007) Kejing Chen et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY