Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases

Mutation analysis of CHCHD2 in Canadian patients with familial Parkinson's disease

(2016) Ming Zhang et al.   NEUROBIOLOGY OF AGING

CHCHD2 gene mutations in familial and sporadic Parkinson's disease

(2016) Chang-he Shi et al.   NEUROBIOLOGY OF AGING

A nonsense mutation inCHCHD2in a patient with Parkinson disease

(2016) Eva Koschmidder et al.   NEUROLOGY

Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson’s disease and meta-analysis of the literature

(2016) Xinglong Yang et al.   PARKINSONISM & RELATED DISORDERS

Mitochondrial Proteins Containing Coiled-Coil-Helix-Coiled-Coil-Helix (CHCH) Domains in Health and Disease

(2016) Nazanine Modjtahedi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Human mitochondrial MIA40 (CHCHD4) is a component of the Fe-S cluster export machinery

(2015) A. Murari et al.   BIOCHEMICAL JOURNAL

Higher Mitochondrial Membrane Potential Induces ROS Production in the Familiar Form of Frontotemporal Dementia with MAPT Mutations

(2015) Noemi Esteras Gallego et al.   BIOPHYSICAL JOURNAL

High prevalence ofCHCHD10mutation in patients with frontotemporal dementia from China

(2015) Bin Jiao et al.   BRAIN

Analysis of theCHCHD10gene in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Spain

(2015) Oriol Dols-Icardo et al.   BRAIN

CHCHD10mutations in Italian patients with sporadic amyotrophic lateral sclerosis: Figure 1

(2015) Dario Ronchi et al.   BRAIN

Mutation analysis ofCHCHD10in different neurodegenerative diseases

(2015) Ming Zhang et al.   BRAIN

CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis

(2015) E. C. Genin et al.   EMBO Molecular Medicine

CHCHD2 and Parkinson's disease

(2015) Jia Nee Foo et al.   LANCET NEUROLOGY

CHCHD2 and Parkinson's disease

(2015) Andreas Puschmann et al.   LANCET NEUROLOGY

CHCHD2 and Parkinson's disease

(2015) Iris E Jansen et al.   LANCET NEUROLOGY

CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study

(2015) Manabu Funayama et al.   LANCET NEUROLOGY

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism

(2015) Siddhesh Aras et al.   MITOCHONDRION

CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration

(2015) Y. Wei et al.   MOLECULAR CANCER RESEARCH

Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis

(2015) Emilie Hangen et al.   MOLECULAR CELL

CHCH10 mutations in an Italian cohort of familial and sporadic amyotrophic lateral sclerosis patients

(2015) Adriano Chiò et al.   NEUROBIOLOGY OF AGING

Mitochondrial targeting sequence variants of theCHCHD2gene are a risk for Lewy body disorders

(2015) Kotaro Ogaki et al.   NEUROLOGY

Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure

(2015) Chengli Ding et al.   Scientific Reports

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

Late onset spinal motor neuronopathy is caused by mutation inCHCHD10

(2014) Sini Penttilä et al.   ANNALS OF NEUROLOGY

Two novel mutations in conserved codons indicate that CHCHD10 is a gene associated with motor neuron disease

(2014) Kathrin Müller et al.   BRAIN

Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis

(2014) Janel O. Johnson et al.   BRAIN

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

(2014) Sylvie Bannwarth et al.   BRAIN

CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients

(2014) Annabelle Chaussenot et al.   NEUROBIOLOGY OF AGING

Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy

(2014) Senda Ajroud-Driss et al.   NEUROGENETICS

Identification and characterization of mitochondrial Mia40 as an iron–sulfur protein

(2013) Michael P. Spiller et al.   BIOCHEMICAL JOURNAL

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation

(2013) Laura Vela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2

(2013) Siddhesh Aras et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of CHCHD1, AURKAIP1, and CRIF1 as new members of the mammalian mitochondrial ribosome

(2013) Emine C. Koc et al.   Frontiers in Physiology

Inaccurately Assembled Cytochrome c Oxidase Can Lead to Oxidative Stress-Induced Growth Arrest

(2012) Manuela Bode et al.   ANTIOXIDANTS & REDOX SIGNALING

Cellular and molecular mechanisms of mitochondrial function

(2012) Laura D. Osellame et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondrial protein import: Common principles and physiological networks

(2012) Jan Dudek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CHCM1/CHCHD6, Novel Mitochondrial Protein Linked to Regulation of Mitofilin and Mitochondrial Cristae Morphology

(2012) Jie An et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting and Import Mechanism of Coiled-coil Helix Coiled-coil Helix Domain-containing Protein 3 (ChChd3) into the Mitochondrial Intermembrane Space

(2012) Manjula Darshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression

(2012) Jun Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of MINOS in Mitochondrial Membrane Architecture: Cristae Morphology and Outer Membrane Interactions Differentially Depend on Mitofilin Domains

(2012) Ralf M. Zerbes et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural characterization of CHCHD5 and CHCHD7: Two atypical human twin CX9C proteins

(2012) Lucia Banci et al.   JOURNAL OF STRUCTURAL BIOLOGY

Sam50 Functions in Mitochondrial Intermembrane Space Bridging and Biogenesis of Respiratory Complexes

(2012) C. Ott et al.   MOLECULAR AND CELLULAR BIOLOGY

A New Link to Mitochondrial Impairment in Tauopathies

(2012) Kathrin L. Schulz et al.   MOLECULAR NEUROBIOLOGY

Cloning and Functional Analysis of FLJ20420: A Novel Transcription Factor for the BAG-1 Promoter

(2012) Hongyu Liu et al.   PLoS One

Disulfide Bond Formation: Sulfhydryl Oxidase ALR Controls Mitochondrial Biogenesis of Human MIA40

(2012) Malgorzata E. Sztolsztener et al.   TRAFFIC

Biogenesis and assembly of eukaryotic cytochrome c oxidase catalytic core

(2011) Ileana C. Soto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

Mitochondrial Disulfide Relay: Redox-regulated Protein Import into the Intermembrane Space

(2011) Johannes M. Herrmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macromolecular organization of ATP synthase and complex I in whole mitochondria

(2011) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Respiratory Chain Dysfunction in Muscle From Patients With Amyotrophic Lateral Sclerosis

(2010) Veronica Crugnola et al.   ARCHIVES OF NEUROLOGY

Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association

(2010) Ruben S.R.M. Martherus et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function

(2010) Manjula Darshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Leigh Syndrome Mutations in the Yeast SURF1 Homolog Reveals a New Member of the Cytochrome Oxidase Assembly Factor Family

(2010) M. Bestwick et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide analysis of eukaryotic twin CX9C proteins

(2010) Gabriele Cavallaro   Molecular BioSystems

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Mitochondrial protein import: from proteomics to functional mechanisms

(2010) Oliver Schmidt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import

(2010) L. Banci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Identification of novel cell migration-promoting genes by a functional genetic screen

(2009) Minchul Seo et al.   FASEB JOURNAL

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria

(2009) Lucia Banci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis

(2009) Joshua M. Baughman et al.   PLoS Genetics

Redox regulation of protein folding in the mitochondrial intermembrane space

(2008) Carla M. Koehler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cell biology of embryonic migration

(2008) Satoshi Kurosaka et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Mitochondrial Biogenesis, Switching the Sorting Pathway of the Intermembrane Space Receptor Mia40

(2008) Agnieszka Chacinska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron–sulfur cluster biogenesis and human disease

(2008) Tracey A. Rouault et al.   TRENDS IN GENETICS