Epigenetic Downregulation of Scn3a Expression by Valproate: a Possible Role in Its Anticonvulsant Activity

Alteration of Scn3a expression is mediated via CpG methylation and MBD2 in mouse hippocampus during postnatal development and seizure condition

(2015) Hai-Jun Li et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line

(2015) Diana Balasubramanian et al.   NEUROPHARMACOLOGY

Rola genu podatności na otyłość (FTO) w rozwoju otyłości — przegląd

(2014) Aleksandra Zdrojowy-Wełna et al.   Endokrynologia Polska

Weight and fat distribution in patients taking valproate: A valproate-discordant gender-matched twin and sibling pair study

(2014) Sandra J. Petty et al.   EPILEPSIA

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Dysregulations of UDP-glucuronosyltransferases in rats with valproic acid and high fat diet induced fatty liver

(2013) Lifang Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

FTO, RNA epigenetics and epilepsy

(2012) Joie Rowles et al.   Epigenetics

Epigenetics and epilepsy

(2012) Avtar Roopra et al.   EPILEPSIA

Differential DNA Methylation Patterns Define Status Epilepticus and Epileptic Tolerance

(2012) S. F. C. Miller-Delaney et al.   JOURNAL OF NEUROSCIENCE

FTO genotype is associated with phenotypic variability of body mass index

(2012) Jian Yang et al.   NATURE

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

Upregulated expression of voltage-gated sodium channel Nav1.3 in cortical lesions of patients with focal cortical dysplasia type IIb

(2012) Sixun Yu et al.   NEUROREPORT

Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine

(2011) C. Cummings et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Promoter Analysis of Mouse Scn3a Gene and Regulation of the Promoter Activity by GC Box and CpG Methylation

(2011) Guang-Fei Deng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Valproate induces DNA demethylation in nuclear extracts from adult mouse brain

(2010) Erbo Dong et al.   Epigenetics

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis

(2010) Irfan A. Qureshi et al.   NEUROBIOLOGY OF DISEASE

Chronic antiepileptic monotherapy, bone metabolism, and body composition in non-institutionalized children

(2009) MARKUS RAUCHENZAUNER et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Increased Reelin Promoter Methylation Is Associated With Granule Cell Dispersion in Human Temporal Lobe Epilepsy

(2009) Katja Kobow et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions

(2009) Mamoru Fukuchi et al.   NEUROSCIENCE RESEARCH

Epigenetics, DNA Methylation, and Chromatin Modifying Drugs

(2008) Moshe Szyf   Annual Review of Pharmacology and Toxicology

Voltage-gated sodium channel Nav1.1, Nav1.3 and β1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat

(2007) Feng Guo et al.   BRAIN RESEARCH BULLETIN